product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse ICOSL (CD275)
catalog :
BE0028-100MG
quantity :
100 mg
price :
2,782.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
HK5.3
reactivity :
mouse
application :
neutralization, flow cytometry, blocking or activating experiments
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; fig 6l
Canel M, Taggart D, Sims A, Lonergan D, Waizenegger I, Serrels A. T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity. elife. 2020;9: pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 7a
  • flow cytometry; mouse; loading ...; fig 5a
Mizuno R, Sugiura D, Shimizu K, Maruhashi T, Watada M, Okazaki I, et al. PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation. Front Immunol. 2019;10:630 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig s3b
Shi B, Geng J, Wang Y, Wei H, Walters B, Li W, et al. Foxp1 Negatively Regulates T Follicular Helper Cell Differentiation and Germinal Center Responses by Controlling Cell Migration and CTLA-4. J Immunol. 2018;200:586-594 pubmed publisher
Raynor J, Karns R, Almanan M, Li K, Divanovic S, Chougnet C, et al. IL-6 and ICOS Antagonize Bim and Promote Regulatory T Cell Accrual with Age. J Immunol. 2015;195:944-52 pubmed publisher
Stone E, Pepper M, Katayama C, Kerdiles Y, Lai C, Emslie E, et al. ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation. Immunity. 2015;42:239-251 pubmed publisher
Huang W, Jeong A, Kannan A, Huang L, August A. IL-2-inducible T cell kinase tunes T regulatory cell development and is required for suppressive function. J Immunol. 2014;193:2267-72 pubmed publisher
Xin L, Jiang T, Chaturvedi V, Kinder J, Ertelt J, Rowe J, et al. Commensal microbes drive intestinal inflammation by IL-17-producing CD4+ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2. Proc Natl Acad Sci U S A. 2014;111:10672-7 pubmed publisher
Srivastava S, Koch M, Pepper M, Campbell D. Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection. J Exp Med. 2014;211:961-74 pubmed publisher
Colino J, Duke L, Snapper C. Noncovalent association of protein and capsular polysaccharide on bacteria-sized latex beads as a model for polysaccharide-specific humoral immunity to intact gram-positive extracellular bacteria. J Immunol. 2013;191:3254-63 pubmed publisher
Baumjohann D, Preite S, Reboldi A, Ronchi F, Ansel K, Lanzavecchia A, et al. Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype. Immunity. 2013;38:596-605 pubmed publisher
Arjunaraja S, Paoletti L, Snapper C. Structurally identical capsular polysaccharide expressed by intact group B streptococcus versus Streptococcus pneumoniae elicits distinct murine polysaccharide-specific IgG responses in vivo. J Immunol. 2012;188:5238-46 pubmed publisher
Arjunaraja S, Massari P, Wetzler L, Lees A, Colino J, Snapper C. The nature of an in vivo anti-capsular polysaccharide response is markedly influenced by the composition and/or architecture of the bacterial subcapsular domain. J Immunol. 2012;188:569-77 pubmed publisher
Choi Y, Kageyama R, Eto D, Escobar T, Johnston R, Monticelli L, et al. ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity. 2011;34:932-46 pubmed publisher
product information
Catalog Number :
BE0028-100MG
Product Name :
InVivoMAb anti-mouse ICOSL (CD275)
Host :
Rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
100 mg
Regular Price :
$4,280.00
Academic Price :
2,782.00 USD
Clone Name :
HK5.3
Isotype :
HK5.3
Immunogen :
Mouse B7-RP1 transfected cell line
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo ICOSL neutralization
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA