product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse CD28
catalog :
BE0015-1-50MG
quantity :
50 mg
price :
1,966.00 USD
clonality :
monoclonal
host :
Syrian golden hamster
conjugate :
nonconjugated
clone name :
37.51
reactivity :
mouse
application :
activation, blocking or activating experiments
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; fig 2e
Canel M, Taggart D, Sims A, Lonergan D, Waizenegger I, Serrels A. T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity. elife. 2020;9: pubmed publisher
  • blocking or activating experiments; mouse; 1 ug/ml; loading ...; fig 3a
Park Y, Cho M, Choi G, Na H, Chung Y. A Critical Regulation of Th17 Cell Responses and Autoimmune Neuro-Inflammation by Ginsenoside Rg3. Biomolecules. 2020;10: pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 2h
Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 5b, 6a
Kotov J, Kotov D, Linehan J, Bardwell V, Gearhart M, Jenkins M. BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors. J Exp Med. 2019;216:1450-1464 pubmed publisher
  • blocking or activating experiments; mouse; 10 ug/ml; loading ...
Anandagoda N, Willis J, Hertweck A, Roberts L, Jackson I, Gökmen M, et al. microRNA-142-mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance. J Clin Invest. 2019;129:1257-1271 pubmed publisher
  • blocking or activating experiments; mouse; 2 ug/ml; loading ...; fig s3a
Karmaus P, Chen X, Lim S, Herrada A, Nguyen T, Xu B, et al. Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity. Nature. 2019;565:101-105 pubmed publisher
  • blocking or activating experiments; mouse; 10 ug/ml; loading ...; fig 4a
Klement J, Paschall A, Redd P, Ibrahim M, Lu C, Yang D, et al. An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion. J Clin Invest. 2018;128:5549-5560 pubmed publisher
  • blocking or activating experiments; mouse; 2 ug/ml; fig 1a
Qiao G, Bucsek M, Winder N, Chen M, Giridharan T, Olejniczak S, et al. β-Adrenergic signaling blocks murine CD8+ T-cell metabolic reprogramming during activation: a mechanism for immunosuppression by adrenergic stress. Cancer Immunol Immunother. 2019;68:11-22 pubmed publisher
Lacher S, Thurm C, Distler U, Mohebiany A, Israel N, Kitic M, et al. NF-κB inducing kinase (NIK) is an essential post-transcriptional regulator of T-cell activation affecting F-actin dynamics and TCR signaling. J Autoimmun. 2018;94:110-121 pubmed publisher
Wendland K, Niss K, Kotarsky K, Wu N, White A, Jendholm J, et al. Retinoic Acid Signaling in Thymic Epithelial Cells Regulates Thymopoiesis. J Immunol. 2018;201:524-532 pubmed publisher
Ron Harel N, Santos D, Ghergurovich J, Sage P, Reddy A, Lovitch S, et al. Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation. Cell Metab. 2016;24:104-17 pubmed publisher
Xu H, Chaudhri V, Wu Z, Biliouris K, Dienger Stambaugh K, Rochman Y, et al. Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8. Nat Immunol. 2015;16:1274-81 pubmed publisher
Choi Y, Gullicksrud J, Xing S, Zeng Z, Shan Q, Li F, et al. LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6. Nat Immunol. 2015;16:980-90 pubmed publisher
Rouhani S, Eccles J, Riccardi P, Peske J, Tewalt E, Cohen J, et al. Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction. Nat Commun. 2015;6:6771 pubmed publisher
Gu A, Zhang S, Wang Y, Xiong H, Curtis T, Wan Y. A critical role for transcription factor Smad4 in T cell function that is independent of transforming growth factor β receptor signaling. Immunity. 2015;42:68-79 pubmed publisher
Tang W, Wang H, Claudio E, Tassi I, Ha H, Saret S, et al. The oncoprotein and transcriptional regulator Bcl-3 governs plasticity and pathogenicity of autoimmune T cells. Immunity. 2014;41:555-66 pubmed publisher
Xiao N, Eto D, Elly C, Peng G, Crotty S, Liu Y. The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells. Nat Immunol. 2014;15:657-66 pubmed publisher
Rabenstein H, Behrendt A, Ellwart J, Naumann R, Horsch M, Beckers J, et al. Differential kinetics of antigen dependency of CD4+ and CD8+ T cells. J Immunol. 2014;192:3507-17 pubmed publisher
Choi Y, Yang J, Yusuf I, Johnston R, Greenbaum J, Peters B, et al. Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory. J Immunol. 2013;190:4014-26 pubmed publisher
Eberlein J, Davenport B, Nguyen T, Victorino F, Sparwasser T, Homann D. Multiple layers of CD80/86-dependent costimulatory activity regulate primary, memory, and secondary lymphocytic choriomeningitis virus-specific T cell immunity. J Virol. 2012;86:1955-70 pubmed publisher
Angkasekwinai P, Chang S, Thapa M, Watarai H, Dong C. Regulation of IL-9 expression by IL-25 signaling. Nat Immunol. 2010;11:250-6 pubmed publisher
product information
Catalog Number :
BE0015-1-50MG
Product Name :
InVivoMAb anti-mouse CD28
Host :
Syrian Hamster
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
50 mg
Regular Price :
$3,024.00
Academic Price :
1,966.00 USD
Clone Name :
37.51
Isotype :
37.51
Immunogen :
C57BL/6 mouse T cell lymphoma EL-4 cells
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vitro T cell stimulation/activation, in vivo CD28 blockade
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA