product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse CD22
catalog :
BE0011-100MG
quantity :
100 mg
price :
2,782.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Cy34.1
reactivity :
mouse
application :
immunoprecipitation, flow cytometry, immunohistochemistry - free floating section
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - free floating section; mouse; 1:100; loading ...; fig 1f
Pluvinage J, Haney M, Smith B, Sun J, Iram T, Bonanno L, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. 2019;568:187-192 pubmed publisher
Säwén P, Lang S, Mandal P, Rossi D, Soneji S, Bryder D. Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis. Cell Rep. 2016;14:2809-18 pubmed publisher
Muller J, Obermeier I, Wöhner M, Brandl C, Mrotzek S, Angermüller S, et al. CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling. Proc Natl Acad Sci U S A. 2013;110:12402-7 pubmed publisher
Wöhner M, Born S, Nitschke L. Human CD22 cannot fully substitute murine CD22 functions in vivo, as shown in a new knockin mouse model. Eur J Immunol. 2012;42:3009-18 pubmed publisher
Efanov A, Zanesi N, Nazaryan N, Santanam U, Palamarchuk A, Croce C, et al. CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation. Leukemia. 2010;24:970-5 pubmed publisher
Duong B, Tian H, Ota T, Completo G, Han S, VELA J, et al. Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo. J Exp Med. 2010;207:173-87 pubmed publisher
Gross A, Lyandres J, Panigrahi A, Prak E, DeFranco A. Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance. J Immunol. 2009;182:5382-92 pubmed publisher
product information
Catalog Number :
BE0011-100MG
Product Name :
InVivoMAb anti-mouse CD22
Host :
Mouse
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
100 mg
Regular Price :
$4,280.00
Academic Price :
2,782.00 USD
Clone Name :
Cy34.1
Isotype :
Cy34.1
Immunogen :
B10.D2 mouse splenocytes
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo B cell depletion in combination with anti-CD19 (clone 1D3) and anti-rat κ Light Chain (clone MAR 18.5), Flow cytometry, Immunoprecipitation
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA