product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-mouse CD8α
catalog :
BE0004-1-50MG
quantity :
50 mg
price :
1,966.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
53-6.7
reactivity :
mouse
application :
western blot, immunocytochemistry, flow cytometry, blocking or activating experiments
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; ; fig 3a
Maruyama J, Reyna R, Kishimoto Urata M, Urata S, Manning J, Harsell N, et al. CD4 T-cell depletion prevents Lassa fever associated hearing loss in the mouse model. PLoS Pathog. 2022;18:e1010557 pubmed publisher
  • blocking or activating experiments; mouse; fig 4g
  • flow cytometry; mouse; loading ...; fig 1a
Chen H, Cong X, Wu C, Wu X, Wang J, Mao K, et al. Intratumoral delivery of CCL25 enhances immunotherapy against triple-negative breast cancer by recruiting CCR9+ T cells. Sci Adv. 2020;6:eaax4690 pubmed publisher
  • blocking or activating experiments; mouse; 150 ug/mouse; fig 1h
Canel M, Taggart D, Sims A, Lonergan D, Waizenegger I, Serrels A. T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity. elife. 2020;9: pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 7h
Daley D, Mani V, Mohan N, Akkad N, Pandian G, Savadkar S, et al. NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma. J Exp Med. 2017;214:1711-1724 pubmed publisher
Wang W, Marinis J, Beal A, Savadkar S, Wu Y, Khan M, et al. RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer. Cancer Cell. 2018;34:757-774.e7 pubmed publisher
Finisguerra V, Di Conza G, Di Matteo M, Serneels J, Costa S, Thompson A, et al. MET is required for the recruitment of anti-tumoural neutrophils. Nature. 2015;522:349-53 pubmed publisher
Yamada D, Elsaesser H, Lux A, Timmerman J, Morrison S, de la Torre J, et al. Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection. Immunity. 2015;42:379-390 pubmed publisher
Christensen A, Skov S, Kvist P, Haase C. Depletion of regulatory T cells in a hapten-induced inflammation model results in prolonged and increased inflammation driven by T cells. Clin Exp Immunol. 2015;179:485-99 pubmed publisher
Walsh K, Teijaro J, Brock L, Fremgen D, Collins P, Rosen H, et al. Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy. J Virol. 2014;88:6281-93 pubmed publisher
Uddin M, Zhang Y, Harton J, MacNamara K, Avram D. TNF-?-dependent hematopoiesis following Bcl11b deletion in T cells restricts metastatic melanoma. J Immunol. 2014;192:1946-53 pubmed publisher
Cyktor J, Carruthers B, Beamer G, Turner J. Clonal expansions of CD8+ T cells with IL-10 secreting capacity occur during chronic Mycobacterium tuberculosis infection. PLoS ONE. 2013;8:e58612 pubmed publisher
Schwager K, Hemmerle T, Aebischer D, Neri D. The immunocytokine L19-IL2 eradicates cancer when used in combination with CTLA-4 blockade or with L19-TNF. J Invest Dermatol. 2013;133:751-758 pubmed publisher
Hervieu A, Rébé C, Vegran F, Chalmin F, Bruchard M, Vabres P, et al. Dacarbazine-mediated upregulation of NKG2D ligands on tumor cells activates NK and CD8 T cells and restrains melanoma growth. J Invest Dermatol. 2013;133:499-508 pubmed publisher
Hafalla J, Claser C, Couper K, Grau G, Renia L, de Souza J, et al. The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. PLoS Pathog. 2012;8:e1002504 pubmed publisher
Chyou S, Benahmed F, Chen J, Kumar V, Tian S, Lipp M, et al. Coordinated regulation of lymph node vascular-stromal growth first by CD11c+ cells and then by T and B cells. J Immunol. 2011;187:5558-67 pubmed publisher
Kumar D, Kirimanjeswara G, Metzger D. Intranasal administration of an inactivated Yersinia pestis vaccine with interleukin-12 generates protective immunity against pneumonic plague. Clin Vaccine Immunol. 2011;18:1925-35 pubmed publisher
Simma O, Zebedin E, Neugebauer N, Schellack C, Pilz A, Chang Rodriguez S, et al. Identification of an indispensable role for tyrosine kinase 2 in CTL-mediated tumor surveillance. Cancer Res. 2009;69:203-11 pubmed publisher
product information
Catalog Number :
BE0004-1-50MG
Product Name :
InVivoMAb anti-mouse CD8α
Host :
Rat
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
50 mg
Regular Price :
$3,024.00
Academic Price :
1,966.00 USD
Clone Name :
53-6.7
Isotype :
53-6.7
Immunogen :
Mouse Spleen Cells or Thymocyte Membranes
Reactivity :
Mouse
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vivo CD8+ T cell depletion, Immunofluorescence, Flow cytometry, Western blot
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA