product summary
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company name :
Bio X Cell
product type :
antibody
product name :
InVivoMAb anti-human CD3
catalog :
BE0001-2-25MG
quantity :
25 mg
price :
1,306.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OKT-3
reactivity :
human
application :
flow cytometry, activation
more info or order :
citations: 9
Reference
Thaker Y, Recino A, Raab M, Jabeen A, Wallberg M, Fernandez N, et al. Activated Cdc42-associated kinase 1 (ACK1) binds the sterile ? motif (SAM) domain of the adaptor SLP-76 and phosphorylates proximal tyrosines. J Biol Chem. 2017;292:6281-6290 pubmed publisher
Liu H, Schneider H, Recino A, Richardson C, Goldberg M, Rudd C. The Immune Adaptor SLP-76 Binds to SUMO-RANGAP1 at Nuclear Pore Complex Filaments to Regulate Nuclear Import of Transcription Factors in T Cells. Mol Cell. 2015;59:840-9 pubmed publisher
Rochman Y, Yukawa M, Kartashov A, Barski A. Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig. PLoS ONE. 2015;10:e0122198 pubmed publisher
Hill E, Ng T, Burton B, Oakley C, Malik K, Wraith D. Glycogen synthase kinase-3 controls IL-10 expression in CD4(+) effector T-cell subsets through epigenetic modification of the IL-10 promoter. Eur J Immunol. 2015;45:1103-15 pubmed publisher
Sturner K, Borgmeyer U, Schulze C, Pless O, Martin R. A multiple sclerosis-associated variant of CBLB links genetic risk with type I IFN function. J Immunol. 2014;193:4439-47 pubmed publisher
Willing A, Leach O, Ufer F, Attfield K, Steinbach K, Kursawe N, et al. CD8? MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis. Eur J Immunol. 2014;44:3119-28 pubmed publisher
Esposito L, Hunter K, Clark J, Rainbow D, Stevens H, Denesha J, et al. Investigation of soluble and transmembrane CTLA-4 isoforms in serum and microvesicles. J Immunol. 2014;193:889-900 pubmed publisher
Wunderlich M, Brooks R, Panchal R, Rhyasen G, Danet Desnoyers G, Mulloy J. OKT3 prevents xenogeneic GVHD and allows reliable xenograft initiation from unfractionated human hematopoietic tissues. Blood. 2014;123:e134-44 pubmed publisher
Lines J, Pantazi E, Mak J, Sempere L, Wang L, O Connell S, et al. VISTA is an immune checkpoint molecule for human T cells. Cancer Res. 2014;74:1924-32 pubmed publisher
product information
Catalog Number :
BE0001-2-25MG
Product Name :
InVivoMAb anti-human CD3
Host :
Mouse
Clonality :
Monoclonal
Label/Conjugation :
No
Antigen Modification :
No
Category :
Antibody
Size :
25 mg
Regular Price :
$2,009.00
Academic Price :
1,306.00 USD
Clone Name :
OKT-3
Isotype :
OKT-3
Immunogen :
Not available or unknown
Reactivity :
Human
Concentration/Amount :
Lot specific,typically between 4-11 mg/ml
Reported Applications :
in vitro T cell stimulation/activation, in vivo T cell depletion in humanized mice, ex vivo T cell inhibition for xenografts, Flow cytometry
Recommended Storage Conditions :
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
more info or order :
company information
Bio X Cell
10 Technology Dr., Suite 2B
Lebanon, NH 03784-1671
customerservice@bxcell.com
http://bxcell.com
1-866-787-3444
headquarters: USA