product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Mouse Ly-6B.2 Alloantigen
catalog :
MCA771GA
quantity :
0.1 mg
price :
257 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
7/4
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
Bio-Rad product webpage
citations: 59
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 3c
Wang K, Ding Y, Xu C, Hao M, Li H, Ding L. Cldn-7 deficiency promotes experimental colitis and associated carcinogenesis by regulating intestinal epithelial integrity. Oncoimmunology. 2021;10:1923910 pubmed publisher
  • immunohistochemistry; mouse; loading ...
Liu Y, Li Y, Loh Y, Singer J, Zhu W, Macia L, et al. Fiber Derived Microbial Metabolites Prevent Acute Kidney Injury Through G-Protein Coupled Receptors and HDAC Inhibition. Front Cell Dev Biol. 2021;9:648639 pubmed publisher
  • immunohistochemistry; mouse; loading ...
  • ELISA; human; loading ...
Kohler D, Granja T, Volz J, Koeppen M, Langer H, Hansmann G, et al. Red blood cell-derived semaphorin 7A promotes thrombo-inflammation in myocardial ischemia-reperfusion injury through platelet GPIb. Nat Commun. 2020;11:1315 pubmed publisher
  • immunohistochemistry; mouse; 1:7500; loading ...; fig 5c
Zhang F, Parayath N, Ene C, Stephan S, Koehne A, Coon M, et al. Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers. Nat Commun. 2019;10:3974 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 2d
Kobayakawa K, Ohkawa Y, Yoshizaki S, Tamaru T, Saito T, Kijima K, et al. Macrophage centripetal migration drives spontaneous healing process after spinal cord injury. Sci Adv. 2019;5:eaav5086 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4b
Urbschat A, Baer P, Zacharowski K, Sprunck V, Scheller B, Raimann F, et al. Systemic TLR2 Antibody Application in Renal Ischaemia and Reperfusion Injury Decreases AKT Phosphorylation and Increases Apoptosis in the Mouse Kidney. Basic Clin Pharmacol Toxicol. 2018;122:223-232 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s10b
Wang X, Cao Q, Yu L, Shi H, Xue B, Shi H. Epigenetic regulation of macrophage polarization and inflammation by DNA methylation in obesity. JCI Insight. 2016;1:e87748 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200
Eichenfield D, Troutman T, Link V, Lam M, Cho H, Gosselin D, et al. Tissue damage drives co-localization of NF-?B, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages. elife. 2016;5: pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:1000; fig 9
Basrai H, Christie K, Turbic A, Bye N, Turnley A. Suppressor of Cytokine Signaling-2 (SOCS2) Regulates the Microglial Response and Improves Functional Outcome after Traumatic Brain Injury in Mice. PLoS ONE. 2016;11:e0153418 pubmed publisher
  • immunohistochemistry; human
Roth J, Köhler D, Schneider M, Granja T, Rosenberger P. Semaphorin 7A Aggravates Pulmonary Inflammation during Lung Injury. PLoS ONE. 2016;11:e0146930 pubmed publisher
  • flow cytometry; mouse; 1:1000
Cherry J, Olschowka J, O Banion M. Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation. J Neuroinflammation. 2015;12:203 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; tbl 1
Crncec I, Pathria P, Svinka J, Eferl R. Induction of colorectal cancer in mice and histomorphometric evaluation of tumors. Methods Mol Biol. 2015;1267:145-64 pubmed publisher
  • flow cytometry; mouse; fig 7
Reynolds A, Kuraoka M, Kelsoe G. Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow. J Immunol. 2015;194:231-42 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 2
Schuhmann M, Kraft P, Stoll G, Lorenz K, Meuth S, Wiendl H, et al. CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke. J Cereb Blood Flow Metab. 2015;35:6-10 pubmed publisher
  • western blot; rat; 1:1000
Goren I, Pfeilschifter J, Frank S. Uptake of neutrophil-derived Ym1 protein distinguishes wound macrophages in the absence of interleukin-4 signaling in murine wound healing. Am J Pathol. 2014;184:3249-61 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:300
Sun Y, Sahbaie P, Liang D, Li W, Clark J. Opioids enhance CXCL1 expression and function after incision in mice. J Pain. 2014;15:856-66 pubmed publisher
  • flow cytometry; mouse
Neumann K, Castineiras Vilarino M, Höckendorf U, Hannesschläger N, Lemeer S, Kupka D, et al. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Immunity. 2014;40:389-99 pubmed publisher
  • immunohistochemistry; mouse
Urbschat A, Zacharowski K, Obermüller N, Rupprecht K, Penzkofer D, Jennewein C, et al. The small fibrinopeptide B?15-42 as renoprotective agent preserving the endothelial and vascular integrity in early ischemia reperfusion injury in the mouse kidney. PLoS ONE. 2014;9:e84432 pubmed publisher
Anquetil T, Solinhac R, Jaffre A, Chicanne G, Viaud J, Darcourt J, et al. PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity. EMBO Rep. 2021;22:e51299 pubmed publisher
Hopp S, Nolte M, Stetter C, Kleinschnitz C, SIREN A, Albert Weissenberger C. Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa. J Neuroinflammation. 2017;14:39 pubmed publisher
Mulay S, Desai J, Kumar S, Eberhard J, Thomasova D, Romoli S, et al. Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis. Nat Commun. 2016;7:10274 pubmed publisher
Levy E, Kornowski R, Gavrieli R, Fratty I, Greenberg G, Waldman M, et al. Long-Lived αMUPA Mice Show Attenuation of Cardiac Aging and Leptin-Dependent Cardioprotection. PLoS ONE. 2015;10:e0144593 pubmed publisher
Patel M, Lin S, Boddicker M, DeMaula C, Connolly B, Bednar B, et al. Quantitative In Vivo Detection of Chlamydia muridarum Associated Inflammation in a Mouse Model Using Optical Imaging. Mediators Inflamm. 2015;2015:264897 pubmed publisher
Ao M, Miyauchi M, Furusho H, Inubushi T, Kitagawa M, Nagasaki A, et al. Dental Infection of Porphyromonas gingivalis Induces Preterm Birth in Mice. PLoS ONE. 2015;10:e0137249 pubmed publisher
Albadawi H, Oklu R, Cormier N, O Keefe R, Heaton J, Kobler J, et al. Hind limb ischemia-reperfusion injury in diet-induced obese mice. J Surg Res. 2014;190:683-91 pubmed publisher
Zheng B, Morgan M, van de Kant H, Garssen J, Folkerts G, Kraneveld A. Transcriptional modulation of pattern recognition receptors in acute colitis in mice. Biochim Biophys Acta. 2013;1832:2162-72 pubmed publisher
Hochhauser E, Cohen R, Waldman M, Maksin A, Isak A, Aravot D, et al. P2Y2 receptor agonist with enhanced stability protects the heart from ischemic damage in vitro and in vivo. Purinergic Signal. 2013;9:633-42 pubmed publisher
Kraft P, Schwarz T, Göb E, Heydenreich N, Brede M, Meuth S, et al. The phosphodiesterase-4 inhibitor rolipram protects from ischemic stroke in mice by reducing blood-brain-barrier damage, inflammation and thrombosis. Exp Neurol. 2013;247:80-90 pubmed publisher
Waldman M, Hochhauser E, Fishbein M, Aravot D, Shainberg A, Sarne Y. An ultra-low dose of tetrahydrocannabinol provides cardioprotection. Biochem Pharmacol. 2013;85:1626-33 pubmed publisher
Koelink P, Overbeek S, Braber S, Morgan M, Henricks P, Abdul Roda M, et al. Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease. Gut. 2014;63:578-87 pubmed publisher
Hsiao H, Sapinoro R, Thatcher T, Croasdell A, Levy E, Fulton R, et al. A novel anti-inflammatory and pro-resolving role for resolvin D1 in acute cigarette smoke-induced lung inflammation. PLoS ONE. 2013;8:e58258 pubmed publisher
Klose A, Zigrino P, Mauch C. Monocyte/macrophage MMP-14 modulates cell infiltration and T-cell attraction in contact dermatitis but not in murine wound healing. Am J Pathol. 2013;182:755-64 pubmed publisher
Furusho H, Miyauchi M, Hyogo H, Inubushi T, Ao M, Ouhara K, et al. Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice. J Gastroenterol. 2013;48:1259-70 pubmed publisher
Famakin B, Mou Y, Spatz M, Lawal M, Hallenbeck J. Downstream Toll-like receptor signaling mediates adaptor-specific cytokine expression following focal cerebral ischemia. J Neuroinflammation. 2012;9:174 pubmed publisher
Heydenreich N, Nolte M, Göb E, Langhauser F, Hofmeister M, Kraft P, et al. C1-inhibitor protects from brain ischemia-reperfusion injury by combined antiinflammatory and antithrombotic mechanisms. Stroke. 2012;43:2457-67 pubmed publisher
Pfeilschifter W, Czech Zechmeister B, Sujak M, Mirceska A, Koch A, Rami A, et al. Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia. Biochem Biophys Res Commun. 2011;413:212-7 pubmed publisher
Cohen R, Shainberg A, Hochhauser E, Cheporko Y, Tobar A, Birk E, et al. UTP reduces infarct size and improves mice heart function after myocardial infarct via P2Y2 receptor. Biochem Pharmacol. 2011;82:1126-33 pubmed publisher
Wiesener N, Schütze T, Lapp S, Lehmann M, Jarasch Althof N, Wutzler P, et al. Analysis of different DNA vaccines for protection of experimental influenza A virus infection. Viral Immunol. 2011;24:321-30 pubmed publisher
McMillan D, Baglole C, Thatcher T, Maggirwar S, Sime P, Phipps R. Lung-targeted overexpression of the NF-?B member RelB inhibits cigarette smoke-induced inflammation. Am J Pathol. 2011;179:125-33 pubmed publisher
Zhang M, Yao B, Wang S, Fan X, Wu G, Yang H, et al. Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice. J Clin Invest. 2011;121:2845-54 pubmed publisher
Smalley Freed W, Efimov A, Short S, Jia P, Zhao Z, Washington M, et al. Adenoma formation following limited ablation of p120-catenin in the mouse intestine. PLoS ONE. 2011;6:e19880 pubmed publisher
Braber S, Overbeek S, Koelink P, Henricks P, Zaman G, Garssen J, et al. CXCR2 antagonists block the N-Ac-PGP-induced neutrophil influx in the airways of mice, but not the production of the chemokine CXCL1. Eur J Pharmacol. 2011;668:443-9 pubmed publisher
Larmonier C, Laubitz D, Thurston R, Bucknam A, Hill F, Midura Kiela M, et al. NHE3 modulates the severity of colitis in IL-10-deficient mice. Am J Physiol Gastrointest Liver Physiol. 2011;300:G998-G1009 pubmed publisher
Kandalam V, Basu R, Abraham T, Wang X, Awad A, Wang W, et al. Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction. Am J Physiol Heart Circ Physiol. 2010;299:H1012-23 pubmed publisher
Mozer A, Whittemore S, Benton R. Spinal microvascular expression of PV-1 is associated with inflammation, perivascular astrocyte loss, and diminished EC glucose transport potential in acute SCI. Curr Neurovasc Res. 2010;7:238-50 pubmed
Fallach R, Shainberg A, Avlas O, Fainblut M, Chepurko Y, Porat E, et al. Cardiomyocyte Toll-like receptor 4 is involved in heart dysfunction following septic shock or myocardial ischemia. J Mol Cell Cardiol. 2010;48:1236-44 pubmed publisher
Czech B, Pfeilschifter W, Mazaheri Omrani N, Strobel M, Kahles T, Neumann Haefelin T, et al. The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia. Biochem Biophys Res Commun. 2009;389:251-6 pubmed publisher
Koehler J, Baggio L, Lamont B, Ali S, Drucker D. Glucagon-like peptide-1 receptor activation modulates pancreatitis-associated gene expression but does not modify the susceptibility to experimental pancreatitis in mice. Diabetes. 2009;58:2148-61 pubmed publisher
Nakamura K, Sasaki T, Cheng X, Iguchi A, Sato K, Kuzuya M. Statin prevents plaque disruption in apoE-knockout mouse model through pleiotropic effect on acute inflammation. Atherosclerosis. 2009;206:355-61 pubmed publisher
MANICONE A, Birkland T, Lin M, Betsuyaku T, Van Rooijen N, Lohi J, et al. Epilysin (MMP-28) restrains early macrophage recruitment in Pseudomonas aeruginosa pneumonia. J Immunol. 2009;182:3866-76 pubmed publisher
Swee M, Wilson C, Wang Y, McGuire J, Parks W. Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients. J Leukoc Biol. 2008;83:1404-12 pubmed publisher
Ip J, Wu Y, Huang J, Zhang L, Pratt R, Dzau V. Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment. Mol Biol Cell. 2007;18:2873-82 pubmed
Baetta R, Silva F, Comparato C, Uzzo M, Eberini I, Bellosta S, et al. Perivascular carotid collar placement induces neointima formation and outward arterial remodeling in mice independent of apolipoprotein E deficiency or Western-type diet feeding. Atherosclerosis. 2007;195:e112-24 pubmed
Morison N, Zhang J, Kaitu u Lino T, Fraser I, Salamonsen L. The long-term actions of etonogestrel and levonorgestrel on decidualized and non-decidualized endometrium in a mouse model mimic some effects of progestogen-only contraceptives in women. Reproduction. 2007;133:309-21 pubmed
Kaitu u Lino T, Morison N, Salamonsen L. Neutrophil depletion retards endometrial repair in a mouse model. Cell Tissue Res. 2007;328:197-206 pubmed
Pineau I, Barrette B, Vallières N, Lacroix S. A novel method for multiple labeling combining in situ hybridization with immunofluorescence. J Histochem Cytochem. 2006;54:1303-13 pubmed
Choi D, Pennathur S, Perier C, Tieu K, Teismann P, Wu D, et al. Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice. J Neurosci. 2005;25:6594-600 pubmed
Kaitu u T, Shen J, Zhang J, Morison N, Salamonsen L. Matrix metalloproteinases in endometrial breakdown and repair: functional significance in a mouse model. Biol Reprod. 2005;73:672-80 pubmed
Thatcher T, McHugh N, Egan R, Chapman R, Hey J, Turner C, et al. Role of CXCR2 in cigarette smoke-induced lung inflammation. Am J Physiol Lung Cell Mol Physiol. 2005;289:L322-8 pubmed
image
image 1 :
Bio-Rad MCA771GA image 1
Published customer image: . Rat anti Mouse Ly-6B.2 antibody, clone 7/4 used for the detection of Ly-6B.2 positive cells by immunohistochemistry. Image caption: . Effect of atorvastatin on platelet and neutrophil infiltration after reperfusion. The infiltration of platelets (upper panel) and neutrophils (lower panel) were evaluated by immunohistochemistry in the 4 chimeric groups that received 40 min of LAD occlusion and 60 min of reperfusion. Platelets and neutrophils were found predominantly in the ischemic area in B6/B6 chimeras. Atorvastatin reduced both platelet and neutrophil infiltration in B6/B6 and B6/KO chimeras, but not in KO/B6 chimeras. From: Tian Y, Linden J, French BA, Yang Z (2014) Atorvastatin at Reperfusion Reduces Myocardial Infarct Size in Mice by Activating eNOS in Bone Marrow-Derived Cells. PLoS ONE 9(12): e114375 .
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA771GA
Description :
Rat anti Mouse Ly-6B.2 Alloantigen
Specificity :
Ly-6B.2 Alloantigen
TargetSpecies :
Mouse
Host :
Rat
Format :
Purified
Isotypes :
IgG2a
Applications :
F,IF,C,WB,P
ApplicationTypes :
Flow Cytometry,Immunofluorescence,Immunohistology - Frozen,Western Blotting,Immunohistology - Paraffin
Clone :
7/4
Quantity :
0.1 mg
Quantity Value :
0.1
Quantity Type :
mg
Entity Formats :
Alexa Fluor® 647,Biotin,FITC,Low Endotoxin,Purified,RPE,Alexa Fluor® 700
UNSPSC :
41116161
Concentration :
IgG concentration 1 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
184
PriceEUR :
257
PriceUSD :
257 USD
PriceCHF :
280
PriceSEK :
2930
PriceNOK :
2925
PriceDKK :
1917
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.