product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Mouse CD11b
catalog :
MCA74GA
quantity :
0.1 mg
price :
257 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
M1/70.15
reactivity :
human, mouse, rat
application :
immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
Bio-Rad product webpage
citations: 17
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 6c
Wiesmeier M, Gautam S, Kirschnek S, Hacker G. Characterisation of Neutropenia-Associated Neutrophil Elastase Mutations in a Murine Differentiation Model In Vitro and In Vivo. PLoS ONE. 2016;11:e0168055 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:600; loading ...; fig 7r
Clausen B, Degn M, Sivasaravanaparan M, Fogtmann T, Andersen M, Trojanowsky M, et al. Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling. Sci Rep. 2016;6:29291 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 5
Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran N, Aiolfi R, et al. IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. EMBO Mol Med. 2016;8:155-70 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:1000; tbl 1
Almolda B, de Labra C, Barrera I, Gruart A, Delgado Garcia J, Villacampa N, et al. Alterations in microglial phenotype and hippocampal neuronal function in transgenic mice with astrocyte-targeted production of interleukin-10. Brain Behav Immun. 2015;45:80-97 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100
  • immunohistochemistry - frozen section; rat; 1:100
Sajjan S, Holsinger R, Fok S, Ebrahimkhani S, Rollo J, Banati R, et al. Up-regulation of matrix metallopeptidase 12 in motor neurons undergoing synaptic stripping. Neuroscience. 2014;274:331-40 pubmed publisher
  • flow cytometry; mouse
Wickström S, Oberg L, Kärre K, Johansson M. A genetic defect in mice that impairs missing self recognition despite evidence for normal maturation and MHC class I-dependent education of NK cells. J Immunol. 2014;192:1577-86 pubmed publisher
Olesen M, Christiansen J, Petersen S, Jensen P, Paslawski W, Romero Ramos M, et al. CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology. Heliyon. 2018;4:e00513 pubmed publisher
Matyas J, O Driscoll C, Yu L, Coll Miro M, Daugherty S, Renn C, et al. Truncated TrkB.T1-Mediated Astrocyte Dysfunction Contributes to Impaired Motor Function and Neuropathic Pain after Spinal Cord Injury. J Neurosci. 2017;37:3956-3971 pubmed publisher
Lin Y, Jean Y, Lee H, Lin S, Pan C, Chen W, et al. Excavatolide B Attenuates Rheumatoid Arthritis through the Inhibition of Osteoclastogenesis. Mar Drugs. 2017;15: pubmed publisher
Loane D, Stoica B, Tchantchou F, Kumar A, Barrett J, Akintola T, et al. Novel mGluR5 positive allosteric modulator improves functional recovery, attenuates neurodegeneration, and alters microglial polarization after experimental traumatic brain injury. Neurotherapeutics. 2014;11:857-69 pubmed publisher
Bartel D, Finger T. Reactive microglia after taste nerve injury: comparison to nerve injury models of chronic pain. F1000Res. 2013;2:65 pubmed publisher
Anderson S, O Callaghan E, Commins S, Coogan A. Does prior sepsis alter subsequent circadian and sickness behaviour response to lipopolysaccharide treatment in mice?. J Neural Transm (Vienna). 2015;122 Suppl 1:S63-73 pubmed publisher
Li B, Shi Y, Shu J, Gao J, Wu P, Tang S. Wingless-type mammary tumor virus integration site family, member 5A (Wnt5a) regulates human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein 120 (gp120)-induced expression of pro-inflammatory cytokines via the Ca2+/calmodulin-dependent pr. J Biol Chem. 2013;288:13610-9 pubmed publisher
Shi Y, Yuan S, Li B, Wang J, Carlton S, Chung K, et al. Regulation of Wnt signaling by nociceptive input in animal models. Mol Pain. 2012;8:47 pubmed publisher
Rigato C, Buckinx R, Le Corronc H, Rigo J, Legendre P. Pattern of invasion of the embryonic mouse spinal cord by microglial cells at the time of the onset of functional neuronal networks. Glia. 2011;59:675-95 pubmed publisher
Miles D, Kernie S. Hypoxic-ischemic brain injury activates early hippocampal stem/progenitor cells to replace vulnerable neuroblasts. Hippocampus. 2008;18:793-806 pubmed publisher
Bannerman P, Hahn A, Soulika A, Gallo V, Pleasure D. Astrogliosis in EAE spinal cord: derivation from radial glia, and relationships to oligodendroglia. Glia. 2007;55:57-64 pubmed
image
image 1 :
Bio-Rad MCA74GA image 1
Immunofluorescence staining of mouse lymph node cryosection using Rat anti Mouse CD11b antibody ( MCA74GA ), green in A and Rat anti Mouse CD8 antibody ( MCA1108 ), red in B, Merged image in C
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA74GA
Description :
Rat anti Mouse CD11b
Specificity :
CD11b
TargetSpecies :
Mouse
Host :
Rat
Format :
Purified
Isotypes :
IgG2b
Applications :
P,IP,F,C,IF
ApplicationTypes :
Immunohistology - Paraffin,Immunoprecipitation,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
Cross Reactivities :
Human,Rabbit
Clone :
M1/70.15
Quantity :
0.1 mg
Quantity Value :
0.1
Quantity Type :
mg
GO Accessions :
GO:0001846,GO:0004872,GO:0008305,GO:0005634,GO:0007159,GO:0007229,GO:0008201,GO:0009897,GO:0030593,GO:0043395,GO:0045123,GO:0050798
GOTerms :
opsonin binding,receptor activity,integrin complex,nucleus,leukocyte cell-cell adhesion,integrin-mediated signaling pathway,heparin binding,external side of plasma membrane,neutrophil chemotaxis,heparan sulfate proteoglycan binding,cellular extravasation,activated T cell proliferation
Uniprot Accessions :
P05555
Gene :
Itgam
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=16409
Published Synonyms :
Integrin Alpha M Chain,MAC-1
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,Biotin,FITC,Low Endotoxin,Pacific Blue®,Purified,RPE,RPE-Alexa Fluor® 750,Alexa Fluor® 700,Amethyst Orange
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
184
PriceEUR :
257
PriceUSD :
257 USD
PriceCHF :
280
PriceSEK :
2930
PriceNOK :
2925
PriceDKK :
1917
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.