Mouse anti Human CD49b | Bio-Rad MCA743 product information

product summary

company name :

Bio-Rad

other brands :

Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology

product type :

antibody

product name :

Mouse anti Human CD49b

catalog :

MCA743

quantity :

0.2 mg

price :

372 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AK7

reactivity :

human

application :

ELISA, immunocytochemistry, flow cytometry, blocking or activating experiments

more info or order :

Bio-Rad product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Iwai L, Payne L, Luczynski M, Chang F, Xu H, Clinton R, et al. Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants. Biochem J. 2013;454:501-13 pubmed publisher
blocking or activating experiments; human; 10 ug/ml immunocytochemistry; human; 10 ug/ml	Xu H, Bihan D, Chang F, Huang P, Farndale R, Leitinger B. Discoidin domain receptors promote Î±1Î²1- and Î±2Î²1-integrin mediated cell adhesion to collagen by enhancing integrin activation. PLoS ONE. 2012;7:e52209 pubmed publisher
	Hamaia S, Pugh N, Raynal N, Némoz B, Stone R, Gullberg D, et al. Mapping of potent and specific binding motifs, GLOGEN and GVOGEA, for integrin ?1?1 using collagen toolkits II and III. J Biol Chem. 2012;287:26019-28 pubmed publisher
	Xia H, Seeman J, Hong J, Hergert P, Bodem V, Jessurun J, et al. Low ?(2)?(1) integrin function enhances the proliferation of fibroblasts from patients with idiopathic pulmonary fibrosis by activation of the ?-catenin pathway. Am J Pathol. 2012;181:222-33 pubmed publisher
	Raynal N, Hamaia S, Siljander P, Maddox B, Peachey A, Fernandez R, et al. Use of synthetic peptides to locate novel integrin alpha2beta1-binding motifs in human collagen III. J Biol Chem. 2006;281:3821-31 pubmed
	Saalmuller A, Lunney J, Daubenberger C, Davis W, Fischer U, Göbel T, et al. Summary of the animal homologue section of HLDA8. Cell Immunol. 2005;236:51-8 pubmed
	Diaz Romero J, Gaillard J, Grogan S, Nesic D, Trub T, Mainil Varlet P. Immunophenotypic analysis of human articular chondrocytes: changes in surface markers associated with cell expansion in monolayer culture. J Cell Physiol. 2005;202:731-42 pubmed
	Kogler G, Sensken S, Airey J, Trapp T, MUSCHEN M, Feldhahn N, et al. A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential. J Exp Med. 2004;200:123-35 pubmed

image

image 1 :

Figure A. FITC conjugated mouse anti human CD14 ( MCA569F ) and RPE conjugated Mouse IgG1 isotype control ( MCA928PE ). Figure B. FITC conjugated mouse anti human CD14 ( MCA569F ) and RPE conjugated mouse anti human CD49b ( MCA743PE ). All experiments performed on red cell lysed Human peripheral blood gated on myeloid cells in the presence of Human SeroBlock ( BUF070A ).

product information

Entity Type :

Monoclonal Antibody

Entity Category :

Antibodies

ProductCode :

MCA743

Description :

Mouse anti Human CD49b

Specificity :

CD49b

TargetSpecies :

Human

Host :

Mouse

Format :

Purified

Isotypes :

IgG1

Applications :

P,F,C,FN

ApplicationTypes :

Immunohistology - Paraffin,Flow Cytometry,Immunohistology - Frozen,Functional Assays

Cross Reactivities :

Cynomolgus monkey,Rhesus Monkey,Baboon

Clone :

AK7

Quantity :

0.2 mg

Quantity Value :

0.2

Quantity Type :

GO Accessions :

GO:0007596,GO:0004872,GO:0005518,GO:0008305,GO:0007160,GO:0007229,GO:0007411,GO:0042802,GO:0044419

GOTerms :

blood coagulation,receptor activity,collagen binding,integrin complex,cell-matrix adhesion,integrin-mediated signaling pathway,axon guidance,identical protein binding,interspecies interaction between organisms

Uniprot Accessions :

P17301

Gene :

ITGA2

GeneID URL :

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3673

Published Synonyms :

Integrin Alpha 2 Chain,VLA-2

Entity Formats :

Biotin,FITC,Purified,RPE

UNSPSC :

41116161

Concentration :

IgG concentration 1.0 mg/ml

Product Form :

Purified IgG - liquid

PriceGBP :

266

PriceEUR :

372

PriceUSD :

372 USD

PriceCHF :

405

PriceSEK :

4055

PriceNOK :

4075

PriceDKK :

2774

more info or order :

Bio-Rad product webpage

company information

Bio-Rad

Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE

antibody_sales_uk@bio-rad.com

https://www.bio-rad-antibodies.com

1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)

headquarters: UK

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