product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Mouse CD8 Alpha
catalog :
MCA609GA
quantity :
0.1 mg
price :
249 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
KT15
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
Bio-Rad product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 0.125 ug/ml; loading ...; fig 6d
Bottermann M, Foss S, Caddy S, Clift D, van Tienen L, Vaysburd M, et al. Complement C4 Prevents Viral Infection through Capsid Inactivation. Cell Host Microbe. 2019;25:617-629.e7 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 4b
Klein J, Moses K, Zelinskyy G, Sody S, Buer J, Lang S, et al. Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth. Nat Commun. 2017;8:14600 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:100; loading ...; fig 3a
Laurent C, Dorothee G, Hunot S, Martin E, Monnet Y, Duchamp M, et al. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain. 2017;140:184-200 pubmed publisher
image
image 1 :
Bio-Rad MCA609GA image 1
Published customer image: . Rat anti Mouse CD4 antibody, clone KT15 used for the detection of CD8 positive lymphocytes by flow cytometry. Image caption: . Peptide boost leads to loss of high avidity responses in vivo . A, schematic of immunization regime. Mice immunized with DNA were boosted at day 63 with DNA or peptide, or with peptide at day 42 followed by DNA at day 63. Responses were analyzed at day 70 for frequency (B) and avidity (C) by measuring responses to increasing peptide concentration in IFN elispot assay, D) normalization of responses to increasing peptide concentration in IFN elispot assay. E, Analysis of antigen specific CTL by pentamer and CD8 staining of immunized splenocytes. F, Analysis of memory phenotype of antigen specific CTL by combination staining for CD62L and CD127 markers. Data is representative of at least three independent experiments. From: Brentville VA, Metheringham RL, Gunn B, Durrant LG (2012) High Avidity Cytotoxic T Lymphocytes Can Be Selected into the Memory Pool but They Are Exquisitely Sensitive to Functional Impairment. PLoS ONE 7(7): e41112 .
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA609GA
Description :
Rat anti Mouse CD8 Alpha
Specificity :
CD8 Alpha
TargetSpecies :
Mouse
Host :
Rat
Format :
Purified
Isotypes :
IgG2a
Applications :
P,F,C,IF
ApplicationTypes :
Immunohistology - Paraffin,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
Clone :
KT15
Quantity :
0.1 mg
Quantity Value :
0.1
Quantity Type :
mg
GO Accessions :
GO:0002456,GO:0016021,GO:0007166,GO:0009897,GO:0042803,GO:0045065,GO:0050850
GOTerms :
T cell mediated immunity,integral to membrane,cell surface receptor linked signaling pathway,external side of plasma membrane,protein homodimerization activity,cytotoxic T cell differentiation,positive regulation of calcium-mediated signaling
Uniprot Accessions :
P01731
Gene :
Cd8a
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=12525
Published Synonyms :
LY-2
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,APC,FITC,Pacific Blue®,Purified,RPE,RPE-Alexa Fluor® 647,RPE-Alexa Fluor® 750,Alexa Fluor® 700,StarBright Blue 700,Amethyst Orange,StarBright Violet 440,StarBright Violet 515,StarBright Violet 610,StarBright Violet 670,StarBright Violet 570,StarBright Violet 710,StarBright Violet 790,StarBright Violet 475,StarBright UltraViolet 400,StarBright UltraViolet 665,StarBright UltraViolet 795,StarBright Violet 760,StarBright UltraViolet 445,StarBright UltraViolet 510,StarBright UltraViolet 740,StarBright UltraViolet 575,StarBright UltraViolet 605,StarBright Blue 580,StarBright Blue 615,StarBright Blue 675,StarBright Blue 765,StarBright Blue 810,StarBright Yellow 575,StarBright Yellow 605,StarBright Yellow 665,StarBright Yellow 800,StarBright Yellow 720,StarBright Red 670,StarBright Red 715,StarBright Red 775,StarBright Red 815
UNSPSC :
41116161
Concentration :
IgG concentration 1 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
178
PriceEUR :
249
PriceUSD :
249 USD
PriceCHF :
271
PriceSEK :
2714
PriceNOK :
2728
PriceDKK :
1856
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.