product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti WIPI2
catalog :
MCA5780GA
quantity :
0.1 mg
price :
264 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2A2
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Bio-Rad product webpage
citations: 15
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:200; loading ...
Dong X, Yang Y, Zou Z, Zhao Y, Ci B, Zhong L, et al. Sorting nexin 5 mediates virus-induced autophagy and immunity. Nature. 2021;589:456-461 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2d
Boukhalfa A, Nascimbeni A, Ramel D, Dupont N, Hirsch E, Gayral S, et al. PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress. Nat Commun. 2020;11:294 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 1i
Fletcher K, Ulferts R, Jacquin E, Veith T, Gammoh N, Arasteh J, et al. The WD40 domain of ATG16L1 is required for its non-canonical role in lipidation of LC3 at single membranes. EMBO J. 2018;37: pubmed publisher
  • immunocytochemistry; human; loading ...; fig s3c
Smith M, Harley M, Kemp A, Wills J, Lee M, Arends M, et al. CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis. Dev Cell. 2018;44:217-232.e11 pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig 7f
Jacquin E, Leclerc Mercier S, Judon C, Blanchard E, Fraitag S, Florey O. Pharmacological modulators of autophagy activate a parallel noncanonical pathway driving unconventional LC3 lipidation. Autophagy. 2017;13:854-867 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 3
Karanasios E, Walker S, Okkenhaug H, Manifava M, Hummel E, Zimmermann H, et al. Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles. Nat Commun. 2016;7:12420 pubmed publisher
  • immunocytochemistry; human; fig 2
Macvicar T, Mannack L, Lees R, Lane J. Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells. Int J Mol Sci. 2015;16:13356-80 pubmed publisher
  • immunocytochemistry; human; 1:200
Karanasios E, Stapleton E, Manifava M, Ktistakis N. Imaging autophagy. Curr Protoc Cytom. 2014;69:12.34.1-12.34.16 pubmed publisher
Kania E, Long J, McEwan D, Welkenhuyzen K, La Rovere R, Luyten T, et al. LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner. Cell Death Dis. 2023;14:436 pubmed publisher
Deitersen J, Berning L, Stuhldreier F, Ceccacci S, Schlütermann D, Friedrich A, et al. High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol. Cell Death Dis. 2021;12:560 pubmed publisher
Pantoom S, Konstantinidis G, Voss S, Han H, Hofnagel O, Li Z, et al. RAB33B recruits the ATG16L1 complex to the phagophore via a noncanonical RAB binding protein. Autophagy. 2020;:1-15 pubmed publisher
Zachari M, Gudmundsson S, Li Z, Manifava M, Shah R, Smith M, et al. Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform. Dev Cell. 2019;50:627-643.e5 pubmed publisher
Wallot Hieke N, Verma N, Schlütermann D, Berleth N, Deitersen J, Böhler P, et al. Systematic analysis of ATG13 domain requirements for autophagy induction. Autophagy. 2018;14:743-763 pubmed publisher
Sakamaki J, Wilkinson S, Hahn M, Tasdemir N, O Prey J, Clark W, et al. Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function. Mol Cell. 2017;66:517-532.e9 pubmed publisher
Macvicar T, Lane J. Impaired OMA1-dependent cleavage of OPA1 and reduced DRP1 fission activity combine to prevent mitophagy in cells that are dependent on oxidative phosphorylation. J Cell Sci. 2014;127:2313-25 pubmed publisher
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA5780GA
Description :
Mouse anti WIPI2
Specificity :
WIPI2
TargetSpecies :
Human
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
WB,P,IF,IP
ApplicationTypes :
Western Blotting,Immunohistology - Paraffin,Immunofluorescence,Immunoprecipitation
Cross Reactivities :
Mouse
Clone :
2A2
Quantity :
0.1 mg
Quantity Value :
0.1
Quantity Type :
mg
GO Accessions :
GO:0000045,GO:0005829,GO:0032266,GO:0034045,GO:0080025,GO:0043234
GOTerms :
autophagic vacuole assembly,cytosol,phosphatidylinositol-3-phosphate binding,pre-autophagosomal structure membrane,phosphatidylinositol-3,5-bisphosphate binding,protein complex
Uniprot Accessions :
Q9Y4P8,Q80W47
Gene :
Wipi2,WIPI2
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=74781, http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26100
Entity Formats :
Purified
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
189
PriceEUR :
264
PriceUSD :
264 USD
PriceCHF :
287
PriceSEK :
2878
PriceNOK :
2892
PriceDKK :
1968
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.