product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Human Eosinophil Major Basic Protein
catalog :
MCA5751
quantity :
0.1 mg
price :
420 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BMK-13
reactivity :
human, pigs
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
Bio-Rad product webpage
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig 1a
Kastenschmidt J, Coulis G, Farahat P, Pham P, Rios R, Cristal T, et al. A stromal progenitor and ILC2 niche promotes muscle eosinophilia and fibrosis-associated gene expression. Cell Rep. 2021;35:108997 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 5d
Simon S, Hu X, Panten J, Grees M, Renders S, Thomas D, et al. Eosinophil accumulation predicts response to melanoma treatment with immune checkpoint inhibitors. Oncoimmunology. 2020;9:1727116 pubmed publisher
  • immunohistochemistry; pigs ; loading ...; fig 6f
Jiang H, Wang D, Wang J, Zhu S, She R, Ren X, et al. Induction of Porcine Dermatitis and Nephropathy Syndrome in Piglets by Infection with Porcine Circovirus Type 3. J Virol. 2019;93: pubmed publisher
  • immunohistochemistry; pigs ; loading ...; fig 6f
Fang Z, Zhong M, Wang Y, Yuan X, Guo H, Yao Y, et al. miR‑381 and miR‑489 suppress cell proliferation and invasion by targeting CUL4B via the Wnt/β‑catenin pathway in gastric cancer. Int J Oncol. 2019;54:733-743 pubmed publisher
  • immunohistochemistry; pigs ; loading ...; fig 6f
Franke F, Muller J, Abal M, Medina E, Nitsche U, Weidmann H, et al. The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer. Cell Mol Gastroenterol Hepatol. 2019;7:33-53 pubmed publisher
  • immunohistochemistry; pigs ; loading ...; fig 6f
Li T, He Z, Zhang X, Tian M, Jiang K, Cheng G, et al. The status of MAPK cascades contributes to the induction and activation of Gata4 and Nkx2.5 during the stepwise process of cardiac differentiation. Cell Signal. 2019;54:17-26 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Dellon E, Speck O, Woodward K, Covey S, Rusin S, Gebhart J, et al. Markers of eosinophilic inflammation for diagnosis of eosinophilic esophagitis and proton pump inhibitor-responsive esophageal eosinophilia: a prospective study. Clin Gastroenterol Hepatol. 2014;12:2015-22 pubmed publisher
Gurtner A, Borrelli C, Gonzalez Perez I, Bach K, Acar I, N xfa xf1 ez N, et al. Active eosinophils regulate host defence and immune responses in colitis. Nature. 2023;615:151-157 pubmed publisher
Dattoli S, Baiula M, De Marco R, Bedini A, Anselmi M, Gentilucci L, et al. DS-70, a novel and potent α4 integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs. Br J Pharmacol. 2018;175:3891-3910 pubmed publisher
image
image 1 :
Bio-Rad MCA5751 image 1
Published customer image: . Mouse anti Human eosinophil major basic protein antibody, clone BMK-13 ( MCA5751 ) used for the demonstration of eosinophil MBP expression in duodenal tissue sections of patients with functional dyspepsia using immunohistochemistry on formalin fixed, paraffin embedded tissue sections. Image caption: . MBP immunostaining of eosinophil degranulation in the representative specimens (D2 and D1) from patients with FD and healthy controls. Magnification, 400×. From: Du L, Shen J, Kim JJ, Yu Y, Ma L, Dai N. Increased Duodenal Eosinophil Degranulation in Patients with Functional Dyspepsia: A Prospective Study. Sci Rep. 2016 Oct 6;6:34305 . This is from an open access article distributed under the terms of the Creative Commons Attribution License .
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA5751
Description :
Mouse anti Human Eosinophil Major Basic Protein
Specificity :
Eosinophil Major Basic Protein
TargetSpecies :
Human
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
P,C
ApplicationTypes :
Immunohistology - Paraffin,Immunohistology - Frozen
Cross Reactivities :
Rat,Guinea Pig
Clone :
BMK-13
Quantity :
0.1 mg
Quantity Value :
0.1
Quantity Type :
mg
GO Accessions :
GO:0042742,GO:0005576,GO:0005529,GO:0030133,GO:0006955,GO:0008201
GOTerms :
defense response to bacterium,extracellular region,sugar binding,transport vesicle,immune response,heparin binding
Uniprot Accessions :
P13727
Gene :
PRG2
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5553
Entity Formats :
Purified
UNSPSC :
41116161
Concentration :
IgG concentration 0.1mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
300
PriceEUR :
420
PriceUSD :
420 USD
PriceCHF :
457
PriceSEK :
4578
PriceNOK :
4601
PriceDKK :
3131
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.