product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Rat CD4 (Domain 1)
catalog :
MCA55G
quantity :
1 mg
price :
660 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
W3/25
reactivity :
mouse, rat
application :
immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
Bio-Rad product webpage
citations: 13
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; rat; 1:100; loading ...; fig 4a
Jörns A, Ishikawa D, Teraoku H, Yoshimoto T, Wedekind D, Lenzen S. Remission of autoimmune diabetes by anti-TCR combination therapies with anti-IL-17A or/and anti-IL-6 in the IDDM rat model of type 1 diabetes. BMC Med. 2020;18:33 pubmed publisher
  • flow cytometry; rat; 1:10; loading ...; fig 4b
Pridans C, Raper A, Davis G, Alves J, Sauter K, Lefèvre L, et al. Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus. J Immunol. 2018;201:2683-2699 pubmed publisher
  • flow cytometry; rat; loading ...; fig s7
Kyratsous N, Bauer I, Zhang G, Pesic M, Bartholomäus I, Mues M, et al. Visualizing context-dependent calcium signaling in encephalitogenic T cells in vivo by two-photon microscopy. Proc Natl Acad Sci U S A. 2017;114:E6381-E6389 pubmed publisher
  • flow cytometry; rat; 1:100; fig s1
Zeka B, Hastermann M, Hochmeister S, Kögl N, Kaufmann N, Schanda K, et al. Highly encephalitogenic aquaporin 4-specific T cells and NMO-IgG jointly orchestrate lesion location and tissue damage in the CNS. Acta Neuropathol. 2015;130:783-98 pubmed publisher
  • flow cytometry; mouse; fig 8
Zschemisch N, Glage S, Wedekind D, Weinstein E, Cui X, Dorsch M, et al. Zinc-finger nuclease mediated disruption of Rag1 in the LEW/Ztm rat. BMC Immunol. 2012;13:60 pubmed publisher
Szittner Z, Papp K, Sándor N, Bajtay Z, Prechl J. Application of fluorescent monocytes for probing immune complexes on antigen microarrays. PLoS ONE. 2013;8:e72401 pubmed publisher
Almolda B, Costa M, Montoya M, Gonzalez B, Castellano B. Increase in Th17 and T-reg lymphocytes and decrease of IL22 correlate with the recovery phase of acute EAE in rat. PLoS ONE. 2011;6:e27473 pubmed publisher
Almolda B, Gonzalez B, Castellano B. Activated microglial cells acquire an immature dendritic cell phenotype and may terminate the immune response in an acute model of EAE. J Neuroimmunol. 2010;223:39-54 pubmed publisher
Nayak B, Friel J, Rempel C, Jones P. Energy-restricted diets result in higher numbers of CD4+, CD8+, immunoglobulins (A, M, and G), and CD45RA cells in spleen and CD4+, immunoglobulin A, and CD45RA cells in colonic lamina propria of rats. Nutr Res. 2009;29:487-93 pubmed publisher
Almolda B, Costa M, Montoya M, Gonzalez B, Castellano B. CD4 microglial expression correlates with spontaneous clinical improvement in the acute Lewis rat EAE model. J Neuroimmunol. 2009;209:65-80 pubmed publisher
Yin R, Huang H, Zhang J, Zhu J, Jing H, Li Z. Dietary n-3 fatty acids attenuate cardiac allograft vasculopathy via activating peroxisome proliferator-activated receptor-gamma. Pediatr Transplant. 2008;12:550-6 pubmed publisher
Yin R, Zhu J, Shao H, Cheng X, Feng X, Li Z, et al. Inhibition of chemokine receptor CCR2 and CCR5 expression contributes to simvastatin-induced attenuation of cardiac allograft vasculopathy. J Heart Lung Transplant. 2007;26:485-93 pubmed
Hofmann N, Lachnit N, Streppel M, Witter B, Neiss W, Guntinas Lichius O, et al. Increased expression of ICAM-1, VCAM-1, MCP-1, and MIP-1 alpha by spinal perivascular macrophages during experimental allergic encephalomyelitis in rats. BMC Immunol. 2002;3:11 pubmed
image
image 1 :
Bio-Rad MCA55G image 1
Figure A. Alexa Fluor 647 conjugated Mouse anti Rat CD8 ( MCA48A647 ) and Alexa Fluor 488 conjugated Mouse IgG1 isotype control ( MCA1209A488 ). Figure B. Alexa Fluor 647 conjugated Mouse anti Rat CD8 ( MCA48A647 ) and Alexa Fluor 488 conjugated Mouse anti Rat CD4 ( MCA55A488 ). All experiments performed on red cell lysed rat blood gated on lymphoid cells in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
Region :
(DOMAIN 1)
ProductCode :
MCA55G
Description :
Mouse anti Rat CD4 (Domain 1)
Specificity :
CD4
TargetSpecies :
Rat
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
P,F,C,IF
ApplicationTypes :
Immunohistology - Paraffin,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
Clone :
W3/25
Quantity :
1 mg
Quantity Value :
1
Quantity Type :
mg
GO Accessions :
GO:0007155,GO:0016021,GO:0006955,GO:0019901,GO:0045058
GOTerms :
cell adhesion,integral to membrane,immune response,protein kinase binding,T cell selection
Uniprot Accessions :
P05540
Gene :
Cd4
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=24932
Entity Formats :
Alexa Fluor® 488,Pacific Blue®,Purified,RPE-Alexa Fluor® 750,Alexa Fluor® 700
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
471
PriceEUR :
660
PriceUSD :
660 USD
PriceCHF :
718
PriceSEK :
7194
PriceNOK :
7230
PriceDKK :
4921
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.