product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Human CD54
catalog :
MCA532T
quantity :
25 µg
price :
249 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
84H10
reactivity :
human
application :
ELISA, immunoprecipitation, flow cytometry
more info or order :
citations: 1
image
image 1 :
Published customer image: . ICAM-1 activates PKC but not PKC II in HMVECLs. A ) At 70% confluence, HMVECLs cells pretreated with 10 ng/ml TNF to induce ICAM-1 expression. At 24 hrs, the cells were suspended and immunolabeled with anti-ICAM-1 antibodies and examined by flow cytometry for ICAM-1 expression. B–D) HMVECLs were pretreated with TNF as in panel A. At 24 hrs, the endothelial cells were nonstimulated (NS) or stimulated with a confluent monolayer of anti-ICAM-1-coated beads or the control anti-PECAM-1-coated beads for 20 minutes in B and D or for the times indicated in C. The cells were lysed and the activation of PKC II and PKC was examined by western blot with B) anti-phospho-PKC IIThr641 or anti-PKC II or C–D) anti-phospho- PKC Thr638 or anti-PKC . Shown are representative blots. Shown are the mean SEM of 3 experiments. NT, nontreated. *, p 0.05 as compared to the nontreated (NT) groups. From: Abdala-Valencia H, Berdnikovs S, Cook-Mills JM (2012). Vitamin E Isoforms Differentially Regulate Intercellular Adhesion Molecule-1 Activation of PKC in Human Microvascular Endothelial Cells. PLoS ONE 7(7): e41054 .
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA532T
Description :
Mouse anti Human CD54
Specificity :
CD54
TargetSpecies :
Human
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
P,E,C,F,IP,FN
ApplicationTypes :
Immunohistology - Paraffin,ELISA,Immunohistology - Frozen,Flow Cytometry,Immunoprecipitation,Functional Assays
Cross Reactivities :
Dog
Clone :
84H10
Quantity :
25 µg
Quantity Value :
25
Quantity Type :
µg
GO Accessions :
GO:0007157,GO:0001910,GO:0002291,GO:0002693,GO:0004888,GO:0005887,GO:0005178,GO:0005615,GO:0007159,GO:0022614,GO:0046813,GO:0050776,GO:0050900,GO:0051856,GO:0060333
GOTerms :
heterophilic cell-cell adhesion,regulation of leukocyte mediated cytotoxicity,T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell,positive regulation of cellular extravasation,transmembrane receptor activity,integral to plasma membrane,integrin binding,extracellular space,leukocyte cell-cell adhesion,membrane to membrane docking,virion attachment, binding of host cell surface receptor,regulation of immune response,leukocyte migration,adhesion to symbiont,interferon-gamma-mediated signaling pathway
Uniprot Accessions :
P05362
Gene :
ICAM1
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3383
Published Synonyms :
ICAM-1
Entity Formats :
Purified
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
178
PriceEUR :
249
PriceUSD :
249 USD
PriceCHF :
271
PriceSEK :
2714
PriceNOK :
2728
PriceDKK :
1856
more info or order :
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.
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