product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Mouse Macrophages/Monocytes
catalog :
MCA519G
quantity :
0.25 mg
price :
384 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MOMA-2
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Bio-Rad product webpage
citations: 39
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; loading ...; fig s3a
Niu X, Pi S, Baral S, Xia Y, He Q, Li Y, et al. P2Y12 Promotes Migration of Vascular Smooth Muscle Cells Through Cofilin Dephosphorylation During Atherogenesis. Arterioscler Thromb Vasc Biol. 2017;37:515-524 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 2b
Dai S, Wang B, Li W, Wang L, Song X, Guo C, et al. Systemic application of 3-methyladenine markedly inhibited atherosclerotic lesion in ApoE-/- mice by modulating autophagy, foam cell formation and immune-negative molecules. Cell Death Dis. 2016;7:e2498 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 6
Lin M, Chen T, Wallingford M, Nguyen N, Yamada S, Sawangmake C, et al. Runx2 Deletion in Smooth muscle Cells Inhibits Vascular Osteochondrogenesis and Calcification but not Atherosclerotic Lesion Formation. Cardiovasc Res. 2016;: pubmed
  • immunohistochemistry; human; 1:500; loading ...; fig s1c
Ouimet M, Hennessy E, van Solingen C, Koelwyn G, Hussein M, Ramkhelawon B, et al. miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and Efflux. Arterioscler Thromb Vasc Biol. 2016;36:942-951 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 5
Wang L, Jiang Y, Song X, Guo C, Zhu F, Wang X, et al. Pdcd4 deficiency enhances macrophage lipoautophagy and attenuates foam cell formation and atherosclerosis in mice. Cell Death Dis. 2016;7:e2055 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 3
Jiang H, Huang S, Li X, Li X, Huang S, Zhang Y, et al. Endothelial tyrosine kinase receptor B prevents VE-cadherin cleavage and protects against atherosclerotic lesion development in ApoE-/- mice. Oncotarget. 2015;6:30640-9 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4
Krishack P, Bhanvadia C, Lukens J, Sontag T, de Beer M, Getz G, et al. Serum Amyloid A Facilitates Early Lesion Development in Ldlr-/- Mice. J Am Heart Assoc. 2015;4: pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 5
He C, Medley S, Hu T, Hinsdale M, Lupu F, Virmani R, et al. PDGFRβ signalling regulates local inflammation and synergizes with hypercholesterolaemia to promote atherosclerosis. Nat Commun. 2015;6:7770 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Wan W, Liu Q, Lionakis M, Marino A, Anderson S, Swamydas M, et al. Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice. Cardiovasc Res. 2015;106:478-87 pubmed publisher
Xu Y, Li Y, Jadhav K, Pan X, Zhu Y, Hu S, et al. Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism. Nat Metab. 2021;3:59-74 pubmed publisher
Aravani D, Morris G, Jones P, Tattersall H, Karamanavi E, Kaiser M, et al. HHIPL1, a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosis. Circulation. 2019;140:500-513 pubmed publisher
Bagchi Chakraborty J, Francis A, Bray T, Masters L, Tsiantoulas D, Nus M, et al. B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B-1-Cell Responses. Arterioscler Thromb Vasc Biol. 2019;39:1379-1389 pubmed publisher
Freemerman A, Zhao L, Pingili A, Teng B, Cozzo A, Fuller A, et al. Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1. J Immunol. 2019;202:1265-1286 pubmed publisher
Tsiantoulas D, Sage A, Göderle L, Ozsvar Kozma M, Murphy D, Porsch F, et al. BAFF Neutralization Aggravates Atherosclerosis. Circulation. 2018;: pubmed publisher
Wang F, Liu Z, Park S, Gwag T, Lu W, Ma M, et al. Myeloid ?-Catenin Deficiency Exacerbates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice. Arterioscler Thromb Vasc Biol. 2018;38:1468-1478 pubmed publisher
Zhou J, Wang Y, Lee V, Zhang G, Medbury H, Williams H, et al. DEC205-DC targeted DNA vaccine against CX3CR1 protects against atherogenesis in mice. PLoS ONE. 2018;13:e0195657 pubmed publisher
Oe Y, Ko M, Fushima T, Sato E, Karumanchi S, Sato H, et al. Hepatic dysfunction and thrombocytopenia induced by excess sFlt1 in mice lacking endothelial nitric oxide synthase. Sci Rep. 2018;8:102 pubmed publisher
Zhang M, Zhu H, Ding Y, Liu Z, Cai Z, Zou M. AMP-activated protein kinase α1 promotes atherogenesis by increasing monocyte-to-macrophage differentiation. J Biol Chem. 2017;292:7888-7903 pubmed publisher
Babaev V, Hebron K, Wiese C, Toth C, Ding L, Zhang Y, et al. Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice. J Lipid Res. 2014;55:2296-308 pubmed publisher
Tarin C, Fernández Laso V, Sastre C, Madrigal Matute J, Gomez M, Zaragoza C, et al. Tumor necrosis factor-like weak inducer of apoptosis or Fn14 deficiency reduce elastase perfusion-induced aortic abdominal aneurysm in mice. J Am Heart Assoc. 2014;3: pubmed publisher
Bonaterra G, Zügel S, Thogersen J, Walter S, Haberkorn U, Strelau J, et al. Growth differentiation factor-15 deficiency inhibits atherosclerosis progression by regulating interleukin-6-dependent inflammatory response to vascular injury. J Am Heart Assoc. 2012;1:e002550 pubmed publisher
Ling M, Ma Z, Wang Y, Qi J, Liu L, Li L, et al. Up-regulated ATP-sensitive potassium channels play a role in increased inflammation and plaque vulnerability in macrophages. Atherosclerosis. 2013;226:348-55 pubmed publisher
Wan W, Lionakis M, Liu Q, Roffe E, Murphy P. Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice. Cardiovasc Res. 2013;97:580-8 pubmed publisher
Yao L, Heuser Baker J, Herlea Pana O, Iida R, Wang Q, Zou M, et al. Bone marrow endothelial progenitors augment atherosclerotic plaque regression in a mouse model of plasma lipid lowering. Stem Cells. 2012;30:2720-31 pubmed publisher
Razani B, Feng C, Coleman T, Emanuel R, Wen H, Hwang S, et al. Autophagy links inflammasomes to atherosclerotic progression. Cell Metab. 2012;15:534-44 pubmed publisher
Fleckman P, Usui M, Zhao G, Underwood R, MAGINNESS M, Marshall A, et al. Cutaneous and inflammatory response to long-term percutaneous implants of sphere-templated porous/solid poly(HEMA) and silicone in mice. J Biomed Mater Res A. 2012;100:1256-68 pubmed publisher
Weingärtner O, Ulrich C, Lutjohann D, Ismail K, Schirmer S, Vanmierlo T, et al. Differential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE-/- mice. Cardiovasc Res. 2011;90:484-92 pubmed publisher
Fukano Y, Usui M, Underwood R, Isenhath S, Marshall A, Hauch K, et al. Epidermal and dermal integration into sphere-templated porous poly(2-hydroxyethyl methacrylate) implants in mice. J Biomed Mater Res A. 2010;94:1172-86 pubmed publisher
Wang S, Wu D, Matthan N, Lamon Fava S, Lecker J, Lichtenstein A. Enhanced aortic macrophage lipid accumulation and inflammatory response in LDL receptor null mice fed an atherogenic diet. Lipids. 2010;45:701-11 pubmed publisher
Braunersreuther V, Pellieux C, Pelli G, Burger F, Steffens S, Montessuit C, et al. Chemokine CCL5/RANTES inhibition reduces myocardial reperfusion injury in atherosclerotic mice. J Mol Cell Cardiol. 2010;48:789-98 pubmed publisher
Yang Y, Tang G, Yan J, Park B, Hoffman A, Tie G, et al. Cellular and molecular mechanism regulating blood flow recovery in acute versus gradual femoral artery occlusion are distinct in the mouse. J Vasc Surg. 2008;48:1546-58 pubmed publisher
Wang S, Wu D, Matthan N, Lamon Fava S, Lecker J, Lichtenstein A. Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse. Atherosclerosis. 2009;204:147-55 pubmed publisher
Saederup N, Chan L, Lira S, Charo I. Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: evidence for independent chemokine functions in atherogenesis. Circulation. 2008;117:1642-8 pubmed publisher
Saban M, Simpson C, Davis C, Wallis G, Knowlton N, Frank M, et al. Discriminators of mouse bladder response to intravesical Bacillus Calmette-Guerin (BCG). BMC Immunol. 2007;8:6 pubmed
Monetti M, Canavesi M, Camera M, Parente R, Paoletti R, Tremoli E, et al. Rosuvastatin displays anti-atherothrombotic and anti-inflammatory properties in apoE-deficient mice. Pharmacol Res. 2007;55:441-9 pubmed
Braunersreuther V, Zernecke A, Arnaud C, Liehn E, Steffens S, Shagdarsuren E, et al. Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice. Arterioscler Thromb Vasc Biol. 2007;27:373-9 pubmed
Espejo C, Penkowa M, Demestre M, Montalban X, Martínez Cáceres E. Time-course expression of CNS inflammatory, neurodegenerative tissue repair markers and metallothioneins during experimental autoimmune encephalomyelitis. Neuroscience. 2005;132:1135-49 pubmed
Monack D, Bouley D, Falkow S. Salmonella typhimurium persists within macrophages in the mesenteric lymph nodes of chronically infected Nramp1+/+ mice and can be reactivated by IFNgamma neutralization. J Exp Med. 2004;199:231-41 pubmed
Kobayashi K, Takahashi N, Jimi E, Udagawa N, Takami M, Kotake S, et al. Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J Exp Med. 2000;191:275-86 pubmed
image
image 1 :
Bio-Rad MCA519G image 1
Staining of mouse peritoneal macrophages with FITC conjugated Rat anti Mouse Macrophages/Monocytes ( MCA519FA ) following permeabilisation with Leucoperm ( BUF09 )
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA519G
Description :
Rat anti Mouse Macrophages/Monocytes
Specificity :
Macrophages/Monocytes
TargetSpecies :
Mouse
Host :
Rat
Format :
Purified
Isotypes :
IgG2b
Applications :
IF,F,C
ApplicationTypes :
Immunofluorescence,Flow Cytometry,Immunohistology - Frozen
Clone :
MOMA-2
Quantity :
0.25 mg
Quantity Value :
0.25
Quantity Type :
mg
Entity Formats :
FITC,Purified
UNSPSC :
41116161
Concentration :
IgG concentration 0.5 mg/ml.
Product Form :
Purified IgG - liquid.
PriceGBP :
274
PriceEUR :
384
PriceUSD :
384 USD
PriceCHF :
418
PriceSEK :
4378
PriceNOK :
4371
PriceDKK :
2864
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.