product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Mouse CD3
catalog :
MCA500G
quantity :
0.25 mg
price :
372 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
KT3
reactivity :
mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Bio-Rad product webpage
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; fig 5
Wang L, Jiang Y, Song X, Guo C, Zhu F, Wang X, et al. Pdcd4 deficiency enhances macrophage lipoautophagy and attenuates foam cell formation and atherosclerosis in mice. Cell Death Dis. 2016;7:e2055 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:300; fig 4
Zahavi T, Lanton T, Divon M, Salmon A, Peretz T, Galun E, et al. Sorafenib treatment during partial hepatectomy reduces tumorgenesis in an inflammation-associated liver cancer model. Oncotarget. 2016;7:4860-70 pubmed publisher
  • immunohistochemistry; mouse; 1:50; fig 4d
Ramnath N, van de Luijtgaarden K, van der Pluijm I, van Nimwegen M, van Heijningen P, Swagemakers S, et al. Extracellular matrix defects in aneurysmal Fibulin-4 mice predispose to lung emphysema. PLoS ONE. 2014;9:e106054 pubmed publisher
  • immunohistochemistry; mouse
Wang B, Dai S, Dong Z, Sun Y, Song X, Guo C, et al. The modulation of endoplasmic reticulum stress by chemical chaperone upregulates immune negative cytokine IL-35 in apolipoprotein E-deficient mice. PLoS ONE. 2014;9:e87787 pubmed publisher
Chrobok N, Jaouën A, Fenrich K, Bol J, Wilhelmus M, Drukarch B, et al. Monocyte behaviour and tissue transglutaminase expression during experimental autoimmune encephalomyelitis in transgenic CX3CR1gfp/gfp mice. Amino Acids. 2017;49:643-658 pubmed publisher
Janssen E, Tohme M, Hedayat M, Leick M, Kumari S, Ramesh N, et al. A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton. J Clin Invest. 2016;126:3837-3851 pubmed publisher
Lee H, Kim M, Kim J, Brown K, Ham A, D Agati V, et al. Critical role of interleukin-17A in murine intestinal ischemia-reperfusion injury. Am J Physiol Gastrointest Liver Physiol. 2013;304:G12-25 pubmed publisher
Salem M, Mony J, Løbner M, Khorooshi R, Owens T. Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice. J Neuroinflammation. 2011;8:181 pubmed publisher
de Sousa A, Reis R, Bento Torres J, Trévia N, Lins N, Passos A, et al. Influence of enriched environment on viral encephalitis outcomes: behavioral and neuropathological changes in albino Swiss mice. PLoS ONE. 2011;6:e15597 pubmed publisher
image
image 1 :
Bio-Rad MCA500G image 1
Figure A. Alexa Fluor 647 conjugated Rat anti Mouse CD4 ( MCA2691A647 ) and Alexa Fluor 488 conjugated Rat IgG2a isotype control ( MCA1212A488 ). Figure B. Alexa Fluor 647 conjugated Rat anti Mouse CD4 ( MCA2691A647 ) and Alexa Fluor 488 conjugated Rat anti Mouse CD3 (MCA500A488). All experiments performed on red cell lysed mouse blood gated on lymphoid cells in the presence of 10% mouse serum. Data acquired on the ZE5 Cell Analyzer.
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA500G
Description :
Rat anti Mouse CD3
Specificity :
CD3
TargetSpecies :
Mouse
Host :
Rat
Format :
Purified
Isotypes :
IgG2a
Applications :
P,F,C
ApplicationTypes :
Immunohistology - Paraffin,Flow Cytometry,Immunohistology - Frozen
Clone :
KT3
Quantity :
0.25 mg
Quantity Value :
0.25
Quantity Type :
mg
GO Accessions :
GO:0016021,GO:0004888,GO:0006461,GO:0007166,GO:0042105,GO:0045059,GO:0007163,GO:0015031,GO:0042981,GO:0046982,GO:0001772,GO:0002669,GO:0008624,GO:0009897,GO:0032729,GO:0032753,GO:0045060,GO:0045086,GO:0045879,GO:0046641,GO:0050731,GO:0050850,GO:0050852,GO:0005515
GOTerms :
integral to membrane,transmembrane receptor activity,protein complex assembly,cell surface receptor linked signaling pathway,alpha-beta T cell receptor complex,positive thymic T cell selection,establishment or maintenance of cell polarity,protein transport,regulation of apoptosis,protein heterodimerization activity,immunological synapse,positive regulation of T cell anergy,induction of apoptosis by extracellular signals,external side of plasma membrane,positive regulation of interferon-gamma production,positive regulation of interleukin-4 production,negative thymic T cell selection,positive regulation of interleukin-2 biosynthetic process,negative regulation of smoothened signaling pathway,positive regulation of alpha-beta T cell proliferation,positive regulation of peptidyl-tyrosine phosphorylation,positive regulation of calcium-mediated signaling,T cell receptor signaling pathway,protein binding
Uniprot Accessions :
P22646,P24161,P11942,P29020,P04235
Gene :
Cd3d,Cd3g,Cd3e,Cd247,Cd247
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=12500, http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=12502, http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=12501, http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=12503, http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=12503
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,APC,FITC,Low Endotoxin,Pacific Blue®,Purified,RPE,StarBright Blue 700,StarBright Violet 440,StarBright Violet 515,StarBright Violet 610,StarBright Violet 670,StarBright Violet 570,StarBright Violet 710,StarBright Violet 790,StarBright Violet 475,StarBright UltraViolet 400,StarBright UltraViolet 665,StarBright UltraViolet 795,StarBright Violet 760,StarBright UltraViolet 445,StarBright UltraViolet 510,StarBright UltraViolet 740,StarBright UltraViolet 575,StarBright UltraViolet 605,StarBright Blue 580,StarBright Blue 615,StarBright Blue 675,StarBright Blue 765,StarBright Blue 810,StarBright Yellow 575,StarBright Yellow 605,StarBright Yellow 665,StarBright Yellow 800,StarBright Yellow 720,StarBright Red 670,StarBright Red 715,StarBright Red 775,StarBright Red 815
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
266
PriceEUR :
372
PriceUSD :
372 USD
PriceCHF :
405
PriceSEK :
4055
PriceNOK :
4075
PriceDKK :
2774
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.