product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Mouse F4/80
catalog :
MCA497R
quantity :
0.25 mg
price :
445 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
Cl:A3-1
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 139
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:1000; fig 2a
Cao S, Hung Y, Wang Y, Chung Y, Qi Y, Ouyang C, et al. Glutamine is essential for overcoming the immunosuppressive microenvironment in malignant salivary gland tumors. Theranostics. 2022;12:6038-6056 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4a
Chang M, Hsu S, Ma L, Chou L, Hung C, Tian Y, et al. Effects of Suramin on Polycystic Kidney Disease in a Mouse Model of Polycystin-1 Deficiency. Int J Mol Sci. 2022;23: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 7a
Huang Z, Liu S, Tang A, Al Rabadi L, Henkemeyer M, Mimche P, et al. Key role for EphB2 receptor in kidney fibrosis. Clin Sci (Lond). 2021;135:2127-2142 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2b, 2e
Sherafat A, Pfeiffer F, Reiss A, Wood W, Nishiyama A. Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor. Nat Commun. 2021;12:2265 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s5c
Bugler Lamb A, Hasib A, Weng X, Hennayake C, Lin C, McCrimmon R, et al. Adipocyte integrin-linked kinase plays a key role in the development of diet-induced adipose insulin resistance in male mice. Mol Metab. 2021;49:101197 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a, s2b
Brownlie D, Doughty Shenton D, Yh Soong D, Nixon C, O Carragher N, M Carlin L, et al. Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β. J Immunother Cancer. 2021;9: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig s4a
Mehta N, Li R, Zhang D, Soomro A, He J, Zhang I, et al. miR299a-5p promotes renal fibrosis by suppressing the antifibrotic actions of follistatin. Sci Rep. 2021;11:88 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1d
Viau A, Baaziz M, Aka A, Mazloum M, Nguyen C, Kuehn E, et al. Tubular STAT3 Limits Renal Inflammation in Autosomal Dominant Polycystic Kidney Disease. J Am Soc Nephrol. 2020;31:1035-1049 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1d
Lindner P, Paul S, Eckstein M, Hampel C, Muenzner J, Erlenbach Wuensch K, et al. EMT transcription factor ZEB1 alters the epigenetic landscape of colorectal cancer cells. Cell Death Dis. 2020;11:147 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2a
Sorrentino C, Yin Z, Ciummo S, Lanuti P, Lu L, Marchisio M, et al. Targeting Interleukin(IL)-30/IL-27p28 signaling in cancer stem-like cells and host environment synergistically inhibits prostate cancer growth and improves survival. J Immunother Cancer. 2019;7:201 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s2a, s2b
Aarts S, Seijkens T, Kusters P, Van Tiel C, Reiche M, den Toom M, et al. Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis. J Pathol. 2019;247:471-480 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 7d
Viau A, Bienaime F, Lukas K, Todkar A, Knoll M, Yakulov T, et al. Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney. EMBO J. 2018;37: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1b
Vogl T, Stratis A, Wixler V, Voller T, Thurainayagam S, Jorch S, et al. Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest. 2018;128:1852-1866 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 6h
Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, et al. Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun. 2018;9:75 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:40; loading ...; fig 7a
McDonough E, Barrett C, Parang B, Mittal M, Smith J, Bradley A, et al. MTG16 is a tumor suppressor in colitis-associated carcinoma. JCI Insight. 2017;2: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
A Gonzalez N, Quintana J, Garcia Silva S, Mazariegos M, González de la Aleja A, Nicolás Ávila J, et al. Phagocytosis imprints heterogeneity in tissue-resident macrophages. J Exp Med. 2017;214:1281-1296 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 2f
Hui X, Zhang M, Gu P, Li K, Gao Y, Wu D, et al. Adipocyte SIRT1 controls systemic insulin sensitivity by modulating macrophages in adipose tissue. EMBO Rep. 2017;18:645-657 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig s1c
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar -, et al. DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas. Cell. 2016;167:1264-1280.e18 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig S7A
Troegeler A, Mercier I, Cougoule C, Pietretti D, Colom A, Duval C, et al. C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells. Proc Natl Acad Sci U S A. 2017;114:E540-E549 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 6a
Naeem A, Tommasi C, Cole C, Brown S, Zhu Y, Way B, et al. A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d. J Allergy Clin Immunol. 2017;139:1228-1241 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:250; loading ...; fig 3c
Guglielmetti C, Le Blon D, Santermans E, Salas Perdomo A, Daans J, De Vocht N, et al. Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages. Glia. 2016;64:2181-2200 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 8
Lamb C, Cholico G, Perkins D, Fewkes M, Oxford J, Lujan T, et al. Aryl Hydrocarbon Receptor Activation by TCDD Modulates Expression of Extracellular Matrix Remodeling Genes during Experimental Liver Fibrosis. Biomed Res Int. 2016;2016:5309328 pubmed
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6a
Vasilopoulou E, Kolatsi Joannou M, Lindenmeyer M, White K, Robson M, Cohen C, et al. Loss of endogenous thymosin β4 accelerates glomerular disease. Kidney Int. 2016;90:1056-1070 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2c
Kim G, Das R, Goduni L, McClellan S, Hazlett L, Mahabeleshwar G. Kruppel-like Factor 6 Promotes Macrophage-mediated Inflammation by Suppressing B Cell Leukemia/Lymphoma 6 Expression. J Biol Chem. 2016;291:21271-21282 pubmed
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s2
Fransén Pettersson N, Duarte N, Nilsson J, Lundholm M, Mayans S, Larefalk A, et al. A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis. PLoS ONE. 2016;11:e0159850 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 5
Tsuboki J, Fujiwara Y, Horlad H, Shiraishi D, Nohara T, Tayama S, et al. Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages. Sci Rep. 2016;6:29588 pubmed publisher
  • flow cytometry; mouse; fig s3
Brandstätter O, Schanz O, Vorac J, König J, Mori T, Maruyama T, et al. Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor. Sci Rep. 2016;6:26091 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 5
Esbona K, Inman D, Saha S, Jeffery J, Schedin P, Wilke L, et al. COX-2 modulates mammary tumor progression in response to collagen density. Breast Cancer Res. 2016;18:35 pubmed publisher
  • immunohistochemistry; mouse; fig 1
Hirasawa M, Takubo K, Osada H, Miyake S, Toda E, Endo M, et al. Angiopoietin-like Protein 2 Is a Multistep Regulator of Inflammatory Neovascularization in a Murine Model of Age-related Macular Degeneration. J Biol Chem. 2016;291:7373-85 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig 5
Watari K, Shibata T, Nabeshima H, Shinoda A, Fukunaga Y, Kawahara A, et al. Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice. Sci Rep. 2016;6:19470 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran N, Aiolfi R, et al. IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. EMBO Mol Med. 2016;8:155-70 pubmed publisher
  • flow cytometry; mouse; loading ...
Leiva M, Quintana J, Ligos J, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;7:10222 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 4a
Ni Y, Nagashimada M, Zhuge F, Zhan L, Nagata N, Tsutsui A, et al. Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. Sci Rep. 2015;5:17192 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:350; loading ...; fig 1g
Johnson V, Xiang M, Chen Z, Junge H. Neurite Mistargeting and Inverse Order of Intraretinal Vascular Plexus Formation Precede Subretinal Vascularization in Vldlr Mutant Mice. PLoS ONE. 2015;10:e0132013 pubmed publisher
  • flow cytometry; mouse
Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, et al. DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance. Immunity. 2015;42:1143-58 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400
Park J, Rasch M, Qiu J, Lund I, Egeblad M. Presence of insulin-like growth factor binding proteins correlates with tumor-promoting effects of matrix metalloproteinase 9 in breast cancer. Neoplasia. 2015;17:421-33 pubmed publisher
  • immunohistochemistry; mouse; 1:200
Tan J, Chan S, Lo C, Deane J, McDonald C, Bernard C, et al. Amnion cell-mediated immune modulation following bleomycin challenge: controlling the regulatory T cell response. Stem Cell Res Ther. 2015;6:8 pubmed publisher
  • flow cytometry; human
Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, et al. Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection. J Immunol. 2015;194:1819-31 pubmed publisher
  • flow cytometry; mouse; fig s1
Evrard M, Chong S, Devi S, Chew W, Lee B, Poidinger M, et al. Visualization of bone marrow monocyte mobilization using Cx3cr1gfp/+Flt3L-/- reporter mouse by multiphoton intravital microscopy. J Leukoc Biol. 2015;97:611-9 pubmed publisher
  • immunohistochemistry; mouse; fig 1
Taniguchi T, Asano Y, Akamata K, Noda S, Takahashi T, Ichimura Y, et al. Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient mice. Arthritis Rheumatol. 2015;67:517-26 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Gangadharan Komala M, Gross S, Mudaliar H, Huang C, Pegg K, Mather A, et al. Inhibition of kidney proximal tubular glucose reabsorption does not prevent against diabetic nephropathy in type 1 diabetic eNOS knockout mice. PLoS ONE. 2014;9:e108994 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig s7
Lin H, Lin S, Chung Y, Vonderfecht S, Camden J, Flodby P, et al. Dynamic involvement of ATG5 in cellular stress responses. Cell Death Dis. 2014;5:e1478 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 7
Uehara Y, Inoue M, Fukuda K, Yamakoshi H, Hosoi Y, Kanda H, et al. Inhibition of β-catenin and STAT3 with a curcumin analog suppresses gastric carcinogenesis in vivo. Gastric Cancer. 2015;18:774-83 pubmed publisher
  • immunohistochemistry - frozen section; mouse
  • flow cytometry; mouse
Liu G, Zhang W, Xiao Y, Lu P. Critical Role of IP-10 on Reducing Experimental Corneal Neovascularization. Curr Eye Res. 2015;40:891-901 pubmed publisher
  • flow cytometry; mouse
Döring M, Lessin I, Frenz T, Spanier J, Kessler A, Tegtmeyer P, et al. M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells. J Virol. 2014;88:13638-50 pubmed publisher
  • flow cytometry; mouse
Bernasconi E, D Angelo F, Michetti P, Velin D. Critical role of the GM-CSF signaling pathway in macrophage pro-repair activities. Pathobiology. 2014;81:183-9 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500
de Bock L, Somers K, Fraussen J, Hendriks J, van Horssen J, Rouwette M, et al. Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis. J Immunol. 2014;193:2147-56 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200
Watatani H, Maeshima Y, Hinamoto N, Yamasaki H, Ujike H, Tanabe K, et al. Vasohibin-1 deficiency enhances renal fibrosis and inflammation after unilateral ureteral obstruction. Physiol Rep. 2014;2: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 6
Kovtunovych G, Ghosh M, Ollivierre W, Weitzel R, Eckhaus M, Tisdale J, et al. Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice. Blood. 2014;124:1522-30 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Lu Z, Kaliberov S, Zhang J, Muz B, Azab A, Sohn R, et al. The myeloid-binding peptide adenoviral vector enables multi-organ vascular endothelial gene targeting. Lab Invest. 2014;94:881-92 pubmed publisher
  • western blot; mouse; 1:500
Johnston Cox H, Eisenstein A, Koupenova M, Carroll S, Ravid K. The macrophage A2B adenosine receptor regulates tissue insulin sensitivity. PLoS ONE. 2014;9:e98775 pubmed publisher
  • flow cytometry; mouse
Forgèt M, Voorhees J, Cole S, Dakhlallah D, Patterson I, Gross A, et al. Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer. PLoS ONE. 2014;9:e98623 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 4
DelGiorno K, Hall J, Takeuchi K, Pan F, Halbrook C, Washington M, et al. Identification and manipulation of biliary metaplasia in pancreatic tumors. Gastroenterology. 2014;146:233-44.e5 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50
Orim F, Bychkov A, Shimamura M, Nakashima M, Ito M, Matsuse M, et al. Thyrotropin signaling confers more aggressive features with higher genomic instability on BRAF(V600E)-induced thyroid tumors in a mouse model. Thyroid. 2014;24:502-10 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Tan J, Chan S, Wallace E, Lim R. Human amnion epithelial cells mediate lung repair by directly modulating macrophage recruitment and polarization. Cell Transplant. 2014;23:319-28 pubmed publisher
  • immunohistochemistry; mouse; 10 ug/ml
Nakao S, Zandi S, Faez S, Kohno R, Hafezi Moghadam A. Discontinuous LYVE-1 expression in corneal limbal lymphatics: dual function as microvalves and immunological hot spots. FASEB J. 2012;26:808-17 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Bulloch K, Miller M, Gal Toth J, Milner T, Gottfried Blackmore A, Waters E, et al. CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain. J Comp Neurol. 2008;508:687-710 pubmed publisher
Ehsanipour A, Sathialingam M, Rad L, de Rutte J, Bierman R, Liang J, et al. Injectable, macroporous scaffolds for delivery of therapeutic genes to the injured spinal cord. APL Bioeng. 2021;5:016104 pubmed publisher
Ehsanipour A, Nguyen T, Aboufadel T, Sathialingam M, Cox P, Xiao W, et al. Injectable, Hyaluronic Acid-Based Scaffolds with Macroporous Architecture for Gene Delivery. Cell Mol Bioeng. 2019;12:399-413 pubmed publisher
Phillips E, Lorch A, Durkes A, Goergen C. Early pathological characterization of murine dissecting abdominal aortic aneurysms. APL Bioeng. 2018;2:046106 pubmed publisher
Short S, Barrett C, Stengel K, Revetta F, Choksi Y, Coburn L, et al. Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma. Oncogene. 2019;38:5091-5106 pubmed publisher
Barikbin R, Berkhout L, Bolik J, Schmidt Arras D, Ernst T, Ittrich H, et al. Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver macrophages of Mdr2-/- mice. Sci Rep. 2018;8:16238 pubmed publisher
Oladipupo S, Kabir A, Smith C, Choi K, Ornitz D. Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1). Sci Rep. 2018;8:14724 pubmed publisher
Kokki E, Karttunen T, Olsson V, Kinnunen K, Yla Herttuala S. Human Vascular Endothelial Growth Factor A165 Expression Induces the Mouse Model of Neovascular Age-Related Macular Degeneration. Genes (Basel). 2018;9: pubmed publisher
Scott C, T Jonck W, Martens L, Todorov H, Sichien D, Soen B, et al. The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages. Immunity. 2018;49:312-325.e5 pubmed publisher
Li Z, Li Y, Overstreet J, Chung S, Niu A, Fan X, et al. Inhibition of Epidermal Growth Factor Receptor Activation Is Associated With Improved Diabetic Nephropathy and Insulin Resistance in Type 2 Diabetes. Diabetes. 2018;67:1847-1857 pubmed publisher
Cerychova R, Bohuslavova R, Papousek F, Sedmera D, Abaffy P, Benes V, et al. Adverse effects of Hif1a mutation and maternal diabetes on the offspring heart. Cardiovasc Diabetol. 2018;17:68 pubmed publisher
Kortlever R, Sodir N, Wilson C, Burkhart D, Pellegrinet L, Brown Swigart L, et al. Myc Cooperates with Ras by Programming Inflammation and Immune Suppression. Cell. 2017;171:1301-1315.e14 pubmed publisher
Liu Z, Cordoba Chacon J, Kineman R, Cronstein B, Muzumdar R, Gong Z, et al. Growth Hormone Control of Hepatic Lipid Metabolism. Diabetes. 2016;65:3598-3609 pubmed
Ahmad F, Chung Y, Tang Y, Hockman S, Liu S, Khan Y, et al. Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue. Sci Rep. 2016;6:28056 pubmed publisher
Haka A, Barbosa Lorenzi V, Lee H, Falcone D, Hudis C, Dannenberg A, et al. Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation. J Lipid Res. 2016;57:980-92 pubmed publisher
Aupperlee M, Zhao Y, Tan Y, Zhu Y, Langohr I, Kirk E, et al. Puberty-specific promotion of mammary tumorigenesis by a high animal fat diet. Breast Cancer Res. 2015;17:138 pubmed publisher
Decock J, Hendrickx W, Thirkettle S, Gutiérrez Fernández A, Robinson S, Edwards D. Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice. Breast Cancer Res. 2015;17:38 pubmed publisher
Barbay V, Houssari M, Mekki M, Banquet S, Edwards Lévy F, Henry J, et al. Role of M2-like macrophage recruitment during angiogenic growth factor therapy. Angiogenesis. 2015;18:191-200 pubmed publisher
Chen S, Okahara F, Osaki N, Shimotoyodome A. Increased GIP signaling induces adipose inflammation via a HIF-1α-dependent pathway and impairs insulin sensitivity in mice. Am J Physiol Endocrinol Metab. 2015;308:E414-25 pubmed publisher
El Machhour F, Keuylian Z, Kavvadas P, Dussaule J, Chatziantoniou C. Activation of Notch3 in Glomeruli Promotes the Development of Rapidly Progressive Renal Disease. J Am Soc Nephrol. 2015;26:1561-75 pubmed publisher
Lundvig D, Scharstuhl A, Cremers N, Pennings S, Te Paske J, van Rheden R, et al. Delayed cutaneous wound closure in HO-2 deficient mice despite normal HO-1 expression. J Cell Mol Med. 2014;18:2488-98 pubmed publisher
Lanaya H, Natarajan A, Komposch K, Li L, Amberg N, Chen L, et al. EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation. Nat Cell Biol. 2014;16:972-7 pubmed publisher
Papadopoulos G, Kramer C, Slocum C, Weinberg E, Hua N, Gudino C, et al. A mouse model for pathogen-induced chronic inflammation at local and systemic sites. J Vis Exp. 2014;:e51556 pubmed publisher
Wong M, Saad S, Zhang J, Gross S, Jarolimek W, Schilter H, et al. Semicarbazide-sensitive amine oxidase (SSAO) inhibition ameliorates kidney fibrosis in a unilateral ureteral obstruction murine model. Am J Physiol Renal Physiol. 2014;307:F908-16 pubmed publisher
Li M, Harel M, Hla T, Ferrer F. Induction of chemokine (C-C motif) ligand 2 by sphingosine-1-phosphate signaling in neuroblastoma. J Pediatr Surg. 2014;49:1286-91 pubmed publisher
Slocum C, Coats S, Hua N, Kramer C, Papadopoulos G, Weinberg E, et al. Distinct lipid a moieties contribute to pathogen-induced site-specific vascular inflammation. PLoS Pathog. 2014;10:e1004215 pubmed publisher
Yoshii A, Kitahara S, Ueta H, Matsuno K, Ezaki T. Role of uterine contraction in regeneration of the murine postpartum endometrium. Biol Reprod. 2014;91:32 pubmed publisher
Henderson N, Arnold T, Katamura Y, Giacomini M, Rodriguez J, McCarty J, et al. Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med. 2013;19:1617-24 pubmed publisher
Zhao Y, Tan Y, Aupperlee M, Langohr I, Kirk E, Troester M, et al. Pubertal high fat diet: effects on mammary cancer development. Breast Cancer Res. 2013;15:R100 pubmed
Partecke L, Gunther C, Hagemann S, Jacobi C, Merkel M, Sendler M, et al. Induction of M2-macrophages by tumour cells and tumour growth promotion by M2-macrophages: a quid pro quo in pancreatic cancer. Pancreatology. 2013;13:508-16 pubmed publisher
Honeyman L, Bazett M, Tomko T, Haston C. MicroRNA profiling implicates the insulin-like growth factor pathway in bleomycin-induced pulmonary fibrosis in mice. Fibrogenesis Tissue Repair. 2013;6:16 pubmed publisher
Lampron A, Pimentel Coelho P, Rivest S. Migration of bone marrow-derived cells into the central nervous system in models of neurodegeneration. J Comp Neurol. 2013;521:3863-76 pubmed publisher
Salathia N, Shi J, Zhang J, Glynne R. An in vivo screen of secreted proteins identifies adiponectin as a regulator of murine cutaneous wound healing. J Invest Dermatol. 2013;133:812-821 pubmed publisher
Hayashi C, Papadopoulos G, Gudino C, Weinberg E, Barth K, Madrigal A, et al. Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen. J Immunol. 2012;189:3681-8 pubmed
Arima M, Yoshida S, Nakama T, Ishikawa K, Nakao S, Yoshimura T, et al. Involvement of periostin in regression of hyaloidvascular system during ocular development. Invest Ophthalmol Vis Sci. 2012;53:6495-503 pubmed
O CONNOR T, Frei N, Sponarova J, Schwarz P, Heikenwalder M, Aguzzi A. Lymphotoxin, but not TNF, is required for prion invasion of lymph nodes. PLoS Pathog. 2012;8:e1002867 pubmed publisher
Kallfass C, Ackerman A, Lienenklaus S, Weiss S, Heimrich B, Staeheli P. Visualizing production of beta interferon by astrocytes and microglia in brain of La Crosse virus-infected mice. J Virol. 2012;86:11223-30 pubmed
Zhang M, Yao B, Yang S, Yang H, Wang S, Fan X, et al. Intrarenal dopamine inhibits progression of diabetic nephropathy. Diabetes. 2012;61:2575-84 pubmed
Murphy S, Shiyun S, Tan J, Chan S, Jenkin G, Wallace E, et al. Human amnion epithelial cells do not abrogate pulmonary fibrosis in mice with impaired macrophage function. Cell Transplant. 2012;21:1477-92 pubmed
Zhang M, Wang S, Yang S, Yang H, Fan X, Takahashi T, et al. Role of blood pressure and the renin-angiotensin system in development of diabetic nephropathy (DN) in eNOS-/- db/db mice. Am J Physiol Renal Physiol. 2012;302:F433-8 pubmed publisher
Ottewell P, Brown H, Jones M, Rogers T, Cross S, Brown N, et al. Combination therapy inhibits development and progression of mammary tumours in immunocompetent mice. Breast Cancer Res Treat. 2012;133:523-36 pubmed publisher
Porcu S, Manchinu M, Marongiu M, Sogos V, Poddie D, Asunis I, et al. Klf1 affects DNase II-alpha expression in the central macrophage of a fetal liver erythroblastic island: a non-cell-autonomous role in definitive erythropoiesis. Mol Cell Biol. 2011;31:4144-54 pubmed publisher
Coward J, Kulbe H, Chakravarty P, Leader D, Vassileva V, Leinster D, et al. Interleukin-6 as a therapeutic target in human ovarian cancer. Clin Cancer Res. 2011;17:6083-96 pubmed publisher
Van Rooyen D, Larter C, Haigh W, Yeh M, Ioannou G, Kuver R, et al. Hepatic free cholesterol accumulates in obese, diabetic mice and causes nonalcoholic steatohepatitis. Gastroenterology. 2011;141:1393-403, 1403.e1-5 pubmed publisher
Zhang M, Yao B, Wang S, Fan X, Wu G, Yang H, et al. Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice. J Clin Invest. 2011;121:2845-54 pubmed publisher
Nakao S, Noda K, Zandi S, Sun D, Taher M, Schering A, et al. VAP-1-mediated M2 macrophage infiltration underlies IL-1?- but not VEGF-A-induced lymph- and angiogenesis. Am J Pathol. 2011;178:1913-21 pubmed publisher
Guma M, Ronacher L, Firestein G, Karin M, Corr M. JNK-1 deficiency limits macrophage-mediated antigen-induced arthritis. Arthritis Rheum. 2011;63:1603-12 pubmed publisher
Murphy S, Lim R, Dickinson H, Acharya R, Rosli S, Jenkin G, et al. Human amnion epithelial cells prevent bleomycin-induced lung injury and preserve lung function. Cell Transplant. 2011;20:909-23 pubmed publisher
Kubota M, Shimmura S, Kubota S, Miyashita H, Kato N, Noda K, et al. Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model. Invest Ophthalmol Vis Sci. 2011;52:427-33 pubmed publisher
Shapiro L, Bialowas McGoey L, Whitaker Azmitia P. Effects of S100B on Serotonergic Plasticity and Neuroinflammation in the Hippocampus in Down Syndrome and Alzheimer's Disease: Studies in an S100B Overexpressing Mouse Model. Cardiovasc Psychiatry Neurol. 2010;2010: pubmed publisher
Nakao S, Zandi S, Hata Y, Kawahara S, Arita R, Schering A, et al. Blood vessel endothelial VEGFR-2 delays lymphangiogenesis: an endogenous trapping mechanism links lymph- and angiogenesis. Blood. 2011;117:1081-90 pubmed publisher
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image
image 1 :
Bio-Rad MCA497R image 1
Dot Blot showing FSC/SSC gated mouse peritoneal macrophages dual stained with F4/80 ( MCA497A647 ) at a 1/5 dilution and CD11b ( MCA74F ) at a 1/5 dilution. Isotype control pair in red. Fc receptors were blocked by Mouse Seroblock ( BUF041B )
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA497R
Description :
Rat anti Mouse F4/80
Specificity :
F4/80
TargetSpecies :
Mouse
Host :
Rat
Format :
Purified
Isotypes :
IgG2b
Applications :
WB,P,IP,F,C,IF,R,EM,RE
ApplicationTypes :
Western Blotting,Immunohistology - Paraffin,Immunoprecipitation,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence,Radioimmunoassays,Immuno-electron Microscopy,Immunohistology - Resin
Clone :
Cl:A3-1
Quantity :
0.25 mg
Quantity Value :
0.25
Quantity Type :
mg
GO Accessions :
GO:0005509,GO:0016021,GO:0004930,GO:0007218,GO:0009897
GOTerms :
calcium ion binding,integral to membrane,G-protein coupled receptor activity,neuropeptide signaling pathway,external side of plasma membrane
Uniprot Accessions :
Q61549
Gene :
Emr1
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=13733
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,APC,Biotin,FITC,Low Endotoxin,Pacific Blue®,Purified,RPE,S/N,Alexa Fluor® 700,StarBright Blue 700,Amethyst Orange,StarBright Violet 440,StarBright Violet 515,StarBright Violet 610,StarBright Violet 670,StarBright Violet 570,StarBright Violet 710,StarBright Violet 790,StarBright Violet 475,StarBright UltraViolet 400,StarBright UltraViolet 665,StarBright UltraViolet 795,StarBright Violet 760,StarBright UltraViolet 445,StarBright UltraViolet 510,StarBright UltraViolet 740,StarBright UltraViolet 575,StarBright UltraViolet 605,StarBright Blue 580,StarBright Blue 615,StarBright Blue 675,StarBright Blue 765,StarBright Blue 810,StarBright Yellow 575,StarBright Yellow 605,StarBright Yellow 665,StarBright Yellow 800,StarBright Yellow 720,StarBright Red 670,StarBright Red 715,StarBright Red 775,StarBright Red 815
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
288
PriceEUR :
464
PriceUSD :
445 USD
PriceCHF :
505
PriceSEK :
5290
PriceNOK :
5282
PriceDKK :
3461
more info or order :
company information
Bio-Rad
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OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
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1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.