Rat anti Mouse F4/80 | Bio-Rad MCA497GA product information

product summary

company name :

Bio-Rad

other brands :

Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology

product type :

antibody

product name :

Rat anti Mouse F4/80

catalog :

MCA497GA

quantity :

0.1 mg

price :

304 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

Cl:A3-1

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other

more info or order :

Bio-Rad product webpage

citations: 154

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; loading ...; fig 5a	Yang C, Su H, An N, Wu H, Guo X, Li Z, et al. AMP-activated protein kinase α2 contributes to acute and chronic hyperuricemic nephropathy via renal urate deposition in a mouse model. Eur J Med Res. 2022;27:176 pubmed publisher
immunohistochemistry; mouse; 1:100; fig 7b	Burl R, Rondini E, Wei H, Pique Regi R, Granneman J. Deconstructing cold-induced brown adipocyte neogenesis in mice. elife. 2022;11: pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:10; loading ...; fig 8b, 8c	Araujo A, Abaurrea A, Azcoaga P, L xf3 pez Velazco J, Manzano S, Rodriguez J, et al. Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment. J Clin Invest. 2022;132: pubmed publisher
other; mouse; loading ...	Van Maldegem F, Valand K, Cole M, Patel H, Angelova M, Rana S, et al. Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry. Nat Commun. 2021;12:5906 pubmed publisher
immunohistochemistry; mouse; fig 6q	Fu H, Gui Y, Liu S, Wang Y, Bastacky S, Qiao Y, et al. The hepatocyte growth factor/c-met pathway is a key determinant of the fibrotic kidney local microenvironment. iScience. 2021;24:103112 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 8a	Sun W, Byon C, Kim D, Choi H, Park J, Joo S, et al. Renoprotective Effects of Maslinic Acid on Experimental Renal Fibrosis in Unilateral Ureteral Obstruction Model via Targeting MyD88. Front Pharmacol. 2021;12:708575 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 7a	Huang Z, Liu S, Tang A, Al Rabadi L, Henkemeyer M, Mimche P, et al. Key role for EphB2 receptor in kidney fibrosis. Clin Sci (Lond). 2021;135:2127-2142 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 8a	Dhawan U, Bhattacharya P, Narayanan S, Manickam V, Aggarwal A, Subramanian M. Hypercholesterolemia Impairs Clearance of Neutrophil Extracellular Traps and Promotes Inflammation and Atherosclerotic Plaque Progression. Arterioscler Thromb Vasc Biol. 2021;41:2598-2615 pubmed publisher
immunohistochemistry - paraffin section; mouse; loading ...; fig 5a	Zhang G, Li R, Li W, Yang S, Sun Q, Yin H, et al. Toll-like receptor 3 ablation prevented high-fat diet-induced obesity and metabolic disorder. J Nutr Biochem. 2021;95:108761 pubmed publisher
immunohistochemistry - paraffin section; mouse; loading ...; fig 7c	Kim D, Park J, Choi H, Kim C, Bae E, Ma S, et al. The critical role of FXR is associated with the regulation of autophagy and apoptosis in the progression of AKI to CKD. Cell Death Dis. 2021;12:320 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:150; loading ...; fig s1g, s1h	Chen J, Sivan U, Tan S, Lippo L, De Angelis J, Labella R, et al. High-resolution 3D imaging uncovers organ-specific vascular control of tissue aging. Sci Adv. 2021;7: pubmed publisher
flow cytometry; mouse; loading ...; fig s1a, s2b	Brownlie D, Doughty Shenton D, Yh Soong D, Nixon C, O Carragher N, M Carlin L, et al. Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β. J Immunother Cancer. 2021;9: pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 4a	Dewhurst M, Ow J, Zafer G, Van Hul N, Wollmann H, Bisteau X, et al. Loss of hepatocyte cell division leads to liver inflammation and fibrosis. PLoS Genet. 2020;16:e1009084 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 4b	Cabañero D, Ramírez López A, Drews E, Schmöle A, Otte D, Wawrzczak Bargiela A, et al. Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain. elife. 2020;9: pubmed publisher
immunohistochemistry; mouse; loading ...; fig 1c	Wang Y, Chaffee T, LaRue R, Huggins D, Witschen P, Ibrahim A, et al. Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice. elife. 2020;9: pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 6b	Witschen P, Chaffee T, Brady N, Huggins D, Knutson T, LaRue R, et al. Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer. Cancers (Basel). 2020;12: pubmed publisher
immunohistochemistry; mouse; 1:500; fig 3f	Chen M, Reed R, Lane A. Chronic Inflammation Directs an Olfactory Stem Cell Functional Switch from Neuroregeneration to Immune Defense. Cell Stem Cell. 2019;25:501-513.e5 pubmed publisher
immunohistochemistry - paraffin section; mouse; loading ...; fig 2a	Sorrentino C, Yin Z, Ciummo S, Lanuti P, Lu L, Marchisio M, et al. Targeting Interleukin(IL)-30/IL-27p28 signaling in cancer stem-like cells and host environment synergistically inhibits prostate cancer growth and improves survival. J Immunother Cancer. 2019;7:201 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2f	Udden S, Kwak Y, Godfrey V, Khan M, Khan S, Loof N, et al. NLRP12 suppresses hepatocellular carcinoma via downregulation of cJun N-terminal kinase activation in the hepatocyte. elife. 2019;8: pubmed publisher
immunohistochemistry; mouse; 1:5000; fig 1d	Lesch B, Tothova Z, Morgan E, Liao Z, Bronson R, Ebert B, et al. Intergenerational epigenetic inheritance of cancer susceptibility in mammals. elife. 2019;8: pubmed publisher
immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4m	Naito H, Iba T, Wakabayashi T, Tai Nagara I, Suehiro J, Jia W, et al. TAK1 Prevents Endothelial Apoptosis and Maintains Vascular Integrity. Dev Cell. 2019;48:151-166.e7 pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig s2a, s2b	Aarts S, Seijkens T, Kusters P, Van Tiel C, Reiche M, den Toom M, et al. Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis. J Pathol. 2019;247:471-480 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 5a	Asano K, Edamatsu M, Hatipoglu O, Inagaki J, Ono M, Ohtsuki T, et al. Host-produced ADAMTS4 Inhibits Early-Stage Tumor Growth. Acta Med Okayama. 2018;72:257-266 pubmed publisher
immunohistochemistry; mouse; 1:25; loading ...; fig 5f	Chakrabarti R, Celià Terrassa T, Kumar S, Hang X, Wei Y, Choudhury A, et al. Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche. Science. 2018;360: pubmed publisher
immunohistochemistry - frozen section; mouse; loading ...; fig 7	Takamori A, Nambu A, Sato K, Yamaguchi S, Matsuda K, Numata T, et al. IL-31 is crucial for induction of pruritus, but not inflammation, in contact hypersensitivity. Sci Rep. 2018;8:6639 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1b	Vogl T, Stratis A, Wixler V, Voller T, Thurainayagam S, Jorch S, et al. Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest. 2018;128:1852-1866 pubmed publisher
immunohistochemistry; mouse; 1:500; loading ...; fig 6h	Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, et al. Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun. 2018;9:75 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 5d	Lingappan K, Maturu P, Liang Y, Jiang W, Wang L, Moorthy B, et al. β-Naphthoflavone treatment attenuates neonatal hyperoxic lung injury in wild type and Cyp1a2-knockout mice. Toxicol Appl Pharmacol. 2018;339:133-142 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3d	Kovtun A, Bergdolt S, Hägele Y, Matthes R, Lambris J, Huber Lang M, et al. Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair. Sci Rep. 2017;7:14061 pubmed publisher
immunohistochemistry - frozen section; mouse; loading ...; fig s1a western blot; mouse; loading ...; fig 1b	Sogawa Y, Nagasu H, Iwase S, Ihoriya C, Itano S, Uchida A, et al. Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice. Sci Rep. 2017;7:8801 pubmed publisher
flow cytometry; mouse; loading ...; fig 1b	A Gonzalez N, Quintana J, Garcia Silva S, Mazariegos M, González de la Aleja A, Nicolás Ávila J, et al. Phagocytosis imprints heterogeneity in tissue-resident macrophages. J Exp Med. 2017;214:1281-1296 pubmed publisher
immunohistochemistry; human; fig 6B	Butler C, Hynds R, Crowley C, Gowers K, Partington L, Hamilton N, et al. Vacuum-assisted decellularization: an accelerated protocol to generate tissue-engineered human tracheal scaffolds. Biomaterials. 2017;124:95-105 pubmed publisher
immunohistochemistry - frozen section; mouse; fig s1c	Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar -, et al. DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas. Cell. 2016;167:1264-1280.e18 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig S7A	Troegeler A, Mercier I, Cougoule C, Pietretti D, Colom A, Duval C, et al. C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells. Proc Natl Acad Sci U S A. 2017;114:E540-E549 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 6a	Naeem A, Tommasi C, Cole C, Brown S, Zhu Y, Way B, et al. A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d. J Allergy Clin Immunol. 2017;139:1228-1241 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 3c	Weyandt J, Carney J, Pavlisko E, Xu M, Counter C. Isoform-Specific Effects of Wild-Type Ras Genes on Carcinogen-Induced Lung Tumorigenesis in Mice. PLoS ONE. 2016;11:e0167205 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:150; fig s1a	Langhi C, Arias N, Rajamoorthi A, Basta J, Lee R, Baldán A. Therapeutic silencing of fat-specific protein 27 improves glycemic control in mouse models of obesity and insulin resistance. J Lipid Res. 2017;58:81-91 pubmed publisher
immunohistochemistry - frozen section; mouse; 4 ug/ml; loading ...; fig 5	Le Blon D, Guglielmetti C, Hoornaert C, Quarta A, Daans J, Dooley D, et al. Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model. J Neuroinflammation. 2016;13:288 pubmed
immunohistochemistry; mouse; loading ...; fig 2	Graus Nunes F, Marinho T, Barbosa da Silva S, Aguila M, Mandarim de Lacerda C, Souza Mello V. Differential effects of angiotensin receptor blockers on pancreatic islet remodelling and glucose homeostasis in diet-induced obese mice. Mol Cell Endocrinol. 2017;439:54-64 pubmed publisher
immunohistochemistry - paraffin section; mouse; loading ...; fig s2	Fransén Pettersson N, Duarte N, Nilsson J, Lundholm M, Mayans S, Larefalk A, et al. A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis. PLoS ONE. 2016;11:e0159850 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 5	Tsuboki J, Fujiwara Y, Horlad H, Shiraishi D, Nohara T, Tayama S, et al. Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages. Sci Rep. 2016;6:29588 pubmed publisher
flow cytometry; mouse; fig s3	BrandstÃ¤tter O, Schanz O, Vorac J, KÃ¶nig J, Mori T, Maruyama T, et al. Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor. Sci Rep. 2016;6:26091 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 5a	Sintusek P, Catapano F, Angkathunkayul N, Marrosu E, Parson S, Morgan J, et al. Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment. PLoS ONE. 2016;11:e0155032 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; fig 5	Robinson E, Tate M, Lockhart S, McPeake C, O Neill K, Edgar K, et al. Metabolically-inactive glucagon-like peptide-1(9-36)amide confers selective protective actions against post-myocardial infarction remodelling. Cardiovasc Diabetol. 2016;15:65 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 5	Du L, Chen X, Cao Y, Lu L, Zhang F, Bornstein S, et al. Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFÎ² signaling. Oncogene. 2016;35:4641-52 pubmed publisher
immunohistochemistry; mouse; fig 1	Hirasawa M, Takubo K, Osada H, Miyake S, Toda E, Endo M, et al. Angiopoietin-like Protein 2 Is a Multistep Regulator of Inflammatory Neovascularization in a Murine Model of Age-related Macular Degeneration. J Biol Chem. 2016;291:7373-85 pubmed publisher
flow cytometry; mouse; loading ...; fig 1b	Foks A, Engelbertsen D, Kuperwaser F, Alberts Grill N, Gonen A, Witztum J, et al. Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice. Arterioscler Thromb Vasc Biol. 2016;36:456-65 pubmed publisher
immunohistochemistry - paraffin section; mouse	Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran N, Aiolfi R, et al. IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. EMBO Mol Med. 2016;8:155-70 pubmed publisher
flow cytometry; mouse; loading ...	Leiva M, Quintana J, Ligos J, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;7:10222 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 4a	Ni Y, Nagashimada M, Zhuge F, Zhan L, Nagata N, Tsutsui A, et al. Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. Sci Rep. 2015;5:17192 pubmed publisher
immunohistochemistry; human; 1:50; fig 5	Lee I, Jung K, Kim I, Lee H, Kim M, Yun S, et al. Human neural stem cells alleviate Alzheimer-like pathology in a mouse model. Mol Neurodegener. 2015;10:38 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:400; fig 4	Binder Gallimidi A, Fischman S, Revach B, Bulvik R, Maliutina A, Rubinstein A, et al. Periodontal pathogens Porphyromonas gingivalis and Fusobacterium nucleatum promote tumor progression in an oral-specific chemical carcinogenesis model. Oncotarget. 2015;6:22613-23 pubmed
flow cytometry; mouse	Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, et al. DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance. Immunity. 2015;42:1143-58 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 9e	Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun. 2015;6:6576 pubmed publisher
flow cytometry; human	Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, et al. Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection. J Immunol. 2015;194:1819-31 pubmed publisher
immunohistochemistry - paraffin section; mouse	Karaca G, Xie G, Moylan C, Swiderska Syn M, Guy C, KrÃ¼ger L, et al. Role of Fn14 in acute alcoholic steatohepatitis in mice. Am J Physiol Gastrointest Liver Physiol. 2015;308:G325-34 pubmed publisher
flow cytometry; mouse; fig s1	Evrard M, Chong S, Devi S, Chew W, Lee B, Poidinger M, et al. Visualization of bone marrow monocyte mobilization using Cx3cr1gfp/+Flt3L-/- reporter mouse by multiphoton intravital microscopy. J Leukoc Biol. 2015;97:611-9 pubmed publisher
immunohistochemistry; mouse; 1:100; fig 5	Wu C, Hung T, Chen C, Ke C, Lee C, Wang P, et al. Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling. PLoS ONE. 2014;9:e113397 pubmed publisher
immunohistochemistry; mouse; fig 1	Taniguchi T, Asano Y, Akamata K, Noda S, Takahashi T, Ichimura Y, et al. Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient mice. Arthritis Rheumatol. 2015;67:517-26 pubmed publisher
immunohistochemistry - frozen section; mouse flow cytometry; mouse	Liu G, Zhang W, Xiao Y, Lu P. Critical Role of IP-10 on Reducing Experimental Corneal Neovascularization. Curr Eye Res. 2015;40:891-901 pubmed publisher
flow cytometry; mouse	DÃ¶ring M, Lessin I, Frenz T, Spanier J, Kessler A, Tegtmeyer P, et al. M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells. J Virol. 2014;88:13638-50 pubmed publisher
flow cytometry; mouse	Bernasconi E, D Angelo F, Michetti P, Velin D. Critical role of the GM-CSF signaling pathway in macrophage pro-repair activities. Pathobiology. 2014;81:183-9 pubmed publisher
immunohistochemistry - paraffin section; human; 1:500	de Bock L, Somers K, Fraussen J, Hendriks J, van Horssen J, Rouwette M, et al. Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis. J Immunol. 2014;193:2147-56 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:200	Watatani H, Maeshima Y, Hinamoto N, Yamasaki H, Ujike H, Tanabe K, et al. Vasohibin-1 deficiency enhances renal fibrosis and inflammation after unilateral ureteral obstruction. Physiol Rep. 2014;2: pubmed publisher
flow cytometry; mouse	Forgèt M, Voorhees J, Cole S, Dakhlallah D, Patterson I, Gross A, et al. Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer. PLoS ONE. 2014;9:e98623 pubmed publisher
immunohistochemistry; mouse	König S, Nitzki F, Uhmann A, Dittmann K, Theiss Suennemann J, Herrmann M, et al. Depletion of cutaneous macrophages and dendritic cells promotes growth of basal cell carcinoma in mice. PLoS ONE. 2014;9:e93555 pubmed publisher
immunohistochemistry; mouse	Chaves L, Bao L, Wang Y, Chang A, Haas M, Quigg R. Loss of CD11b exacerbates murine complement-mediated tubulointerstitial nephritis. PLoS ONE. 2014;9:e92051 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:50	Jha P, Knopf A, Koefeler H, Mueller M, Lackner C, Hoefler G, et al. Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH). Biochim Biophys Acta. 2014;1842:959-70 pubmed publisher
immunohistochemistry; mouse; 1:500	Ikeda Y, Ozono I, Tajima S, Imao M, Horinouchi Y, Izawa Ishizawa Y, et al. Iron chelation by deferoxamine prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction. PLoS ONE. 2014;9:e89355 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:50	Orim F, Bychkov A, Shimamura M, Nakashima M, Ito M, Matsuse M, et al. Thyrotropin signaling confers more aggressive features with higher genomic instability on BRAF(V600E)-induced thyroid tumors in a mouse model. Thyroid. 2014;24:502-10 pubmed publisher
immunohistochemistry - paraffin section; mouse	Li S, Li B, Jiang H, Wang Y, Qu M, Duan H, et al. Macrophage depletion impairs corneal wound healing after autologous transplantation in mice. PLoS ONE. 2013;8:e61799 pubmed publisher
	Itoh M, Tamura A, Kanai S, Tanaka M, Kanamori Y, Shirakawa I, et al. Lysosomal cholesterol overload in macrophages promotes liver fibrosis in a mouse model of NASH. J Exp Med. 2023;220: pubmed publisher
	Schwabenland M, Bruck W, Priller J, Stadelmann C, Lassmann H, Prinz M. Analyzing microglial phenotypes across neuropathologies: a practical guide. Acta Neuropathol. 2021;142:923-936 pubmed publisher
	Gangoso E, Southgate B, Bradley L, Rus S, Gálvez Cancino F, McGivern N, et al. Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion. Cell. 2021;184:2454-2470.e26 pubmed publisher
	Nakao Y, Fukuda T, Zhang Q, Sanui T, Shinjo T, Kou X, et al. Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss. Acta Biomater. 2021;122:306-324 pubmed publisher
	Qiang L, Yang S, Cui Y, He Y. Keratinocyte autophagy enables the activation of keratinocytes and fibroblasts and facilitates wound healing. Autophagy. 2020;:1-16 pubmed publisher
	de la Fuente Fernández M, González Hedström D, Amor S, Tejera Muñoz A, Fernandez N, Monge L, et al. Supplementation with a Carob (Ceratonia siliqua L.) Fruit Extract Attenuates the Cardiometabolic Alterations Associated with Metabolic Syndrome in Mice. Antioxidants (Basel). 2020;9: pubmed publisher
	Sasaki K, Himeno A, Nakagawa T, Sasaki Y, Kiyonari H, Iwai K. Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death. Nat Commun. 2019;10:3878 pubmed publisher
	Mori K, Tsuchiya K, Nakamura S, Miyachi Y, Shiba K, Ogawa Y, et al. Ipragliflozin-induced adipose expansion inhibits cuff-induced vascular remodeling in mice. Cardiovasc Diabetol. 2019;18:83 pubmed publisher
	Phillips E, Lorch A, Durkes A, Goergen C. Early pathological characterization of murine dissecting abdominal aortic aneurysms. APL Bioeng. 2018;2:046106 pubmed publisher
	Pajed L, Wagner C, Taschler U, Schreiber R, Kolleritsch S, Fawzy N, et al. Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation. J Biol Chem. 2019;294:9118-9133 pubmed publisher
	Gopal R, Lee B, McHugh K, Rich H, Ramanan K, Mandalapu S, et al. STAT2 Signaling Regulates Macrophage Phenotype During Influenza and Bacterial Super-Infection. Front Immunol. 2018;9:2151 pubmed publisher
	Yoshida S, Yamahara K, Kume S, Koya D, Yasuda Yamahara M, Takeda N, et al. Role of dietary amino acid balance in diet restriction-mediated lifespan extension, renoprotection, and muscle weakness in aged mice. Aging Cell. 2018;17:e12796 pubmed publisher
	Yang J, Park K, Cho S. Inhibition of the CD36 receptor reduces visceral fat accumulation and improves insulin resistance in obese mice carrying the BDNF-Val66Met variant. J Biol Chem. 2018;293:13338-13348 pubmed publisher
	Ali Z, Islam A, Sherrell P, Le Moine M, Lolas G, Syrigos K, et al. Adjustable delivery of pro-angiogenic FGF-2 by alginate:collagen microspheres. Biol Open. 2018;7: pubmed publisher
	Maybin J, Murray A, Saunders P, Hirani N, Carmeliet P, Critchley H. Hypoxia and hypoxia inducible factor-1α are required for normal endometrial repair during menstruation. Nat Commun. 2018;9:295 pubmed publisher
	Chaqour J, Lee S, Ravichandra A, Chaqour B. Abscisic acid - an anti-angiogenic phytohormone that modulates the phenotypical plasticity of endothelial cells and macrophages. J Cell Sci. 2018;131: pubmed publisher
	Kortlever R, Sodir N, Wilson C, Burkhart D, Pellegrinet L, Brown Swigart L, et al. Myc Cooperates with Ras by Programming Inflammation and Immune Suppression. Cell. 2017;171:1301-1315.e14 pubmed publisher
	Rajamoorthi A, Arias N, Basta J, Lee R, Baldán A. Amelioration of diet-induced steatohepatitis in mice following combined therapy with ASO-Fsp27 and fenofibrate. J Lipid Res. 2017;58:2127-2138 pubmed publisher
	Mass E, Jacome Galarza C, Blank T, Lazarov T, Durham B, Ozkaya N, et al. A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease. Nature. 2017;549:389-393 pubmed publisher
	McAuley E, Mustafi D, Simons B, Valek R, Zamora M, Markiewicz E, et al. Magnetic Resonance Imaging and Molecular Characterization of a Hormone-Mediated Murine Model of Prostate Enlargement and Bladder Outlet Obstruction. Am J Pathol. 2017;187:2378-2387 pubmed publisher
	Yu L, Moriguchi T, Kaneko H, Hayashi M, Hasegawa A, Nezu M, et al. Reducing Inflammatory Cytokine Production from Renal Collecting Duct Cells by Inhibiting GATA2 Ameliorates Acute Kidney Injury. Mol Cell Biol. 2017;37: pubmed publisher
	Zhang W, Chen L, Ma K, Zhao Y, Liu X, Wang Y, et al. Polarization of macrophages in the tumor microenvironment is influenced by EGFR signaling within colon cancer cells. Oncotarget. 2016;7:75366-75378 pubmed publisher
	Komiya C, Tsuchiya K, Shiba K, Miyachi Y, Furuke S, Shimazu N, et al. Ipragliflozin Improves Hepatic Steatosis in Obese Mice and Liver Dysfunction in Type 2 Diabetic Patients Irrespective of Body Weight Reduction. PLoS ONE. 2016;11:e0151511 pubmed publisher
	Bachstetter A, Zhou Z, Rowe R, Xing B, Goulding D, Conley A, et al. MW151 Inhibited IL-1β Levels after Traumatic Brain Injury with No Effect on Microglia Physiological Responses. PLoS ONE. 2016;11:e0149451 pubmed publisher
	Muramatsu Kato K, Itoh H, Kohmura Kobayashi Y, Ferdous U, Tamura N, Yaguchi C, et al. Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress. Sci Rep. 2015;5:16867 pubmed publisher
	Black K, Lin B, Wonder E, Desai S, Chung E, Ulery B, et al. Biocompatibility and characterization of a peptide amphiphile hydrogel for applications in peripheral nerve regeneration. Tissue Eng Part A. 2015;21:1333-42 pubmed publisher
	Sanz Moreno A, Fuhrmann D, Zankel A, Reingruber H, Kern L, Meijer D, et al. Late onset neuropathy with spontaneous clinical remission in mice lacking the POZ domain of the transcription factor Myc-interacting zinc finger protein 1 (Miz1) in Schwann cells. J Biol Chem. 2015;290:727-43 pubmed publisher
	Lam G, Sefton M. Tuning graft- and host-derived vascularization in modular tissue constructs: a potential role of HIF1 activation. Tissue Eng Part A. 2015;21:803-16 pubmed publisher
	Lee C, Zhan Q, Lezcano C, Frank M, Huang J, Larson A, et al. Nestin depletion induces melanoma matrix metalloproteinases and invasion. Lab Invest. 2014;94:1382-95 pubmed publisher
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image

image 1 :

Dot Blot showing FSC/SSC gated mouse peritoneal macrophages dual stained with F4/80 ( MCA497A647 ) at a 1/5 dilution and CD11b ( MCA74F ) at a 1/5 dilution. Isotype control pair in red. Fc receptors were blocked by Mouse Seroblock ( BUF041B )

product information

Entity Type :

Monoclonal Antibody

Entity Category :

Antibodies

ProductCode :

MCA497GA

Description :

Rat anti Mouse F4/80

Specificity :

F4/80

TargetSpecies :

Mouse

Host :

Rat

Format :

Purified

Isotypes :

IgG2b

Applications :

F,IF,C,WB,P,IP,R,RE,EM

ApplicationTypes :

Flow Cytometry,Immunofluorescence,Immunohistology - Frozen,Western Blotting,Immunohistology - Paraffin,Immunoprecipitation,Radioimmunoassays,Immunohistology - Resin,Immuno-electron Microscopy

Clone :

Cl:A3-1

Quantity :

0.1 mg

Quantity Value :

0.1

Quantity Type :

GO Accessions :

GO:0005509,GO:0016021,GO:0004930,GO:0007218,GO:0009897

GOTerms :

calcium ion binding,integral to membrane,G-protein coupled receptor activity,neuropeptide signaling pathway,external side of plasma membrane

Uniprot Accessions :

Q61549

Gene :

Emr1

GeneID URL :

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=13733

Entity Formats :

Alexa Fluor® 488,Alexa Fluor® 647,APC,Biotin,FITC,Low Endotoxin,Pacific Blue®,Purified,RPE,S/N,Alexa Fluor® 700,StarBright Blue 700,Amethyst Orange,StarBright Violet 440,StarBright Violet 515,StarBright Violet 610,StarBright Violet 670,StarBright Violet 570,StarBright Violet 710,StarBright Violet 790,StarBright Violet 475,StarBright UltraViolet 400,StarBright UltraViolet 665,StarBright UltraViolet 795,StarBright Violet 760,StarBright UltraViolet 445,StarBright UltraViolet 510,StarBright UltraViolet 740,StarBright UltraViolet 575,StarBright UltraViolet 605,StarBright Blue 580,StarBright Blue 615,StarBright Blue 675,StarBright Blue 765,StarBright Blue 810,StarBright Yellow 575,StarBright Yellow 605,StarBright Yellow 665,StarBright Yellow 800,StarBright Yellow 720,StarBright Red 670,StarBright Red 715,StarBright Red 775,StarBright Red 815

UNSPSC :

41116161

Concentration :

IgG concentration 1.0 mg/ml

Product Form :

Purified IgG - liquid

PriceGBP :

190

PriceEUR :

330

PriceUSD :

304 USD

PriceCHF :

359

PriceSEK :

3762

PriceNOK :

3756

PriceDKK :

2461

more info or order :

Bio-Rad product webpage