product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Mouse F4/80
catalog :
MCA497G
quantity :
0.5 mg
price :
618 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
Cl:A3-1
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 99
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2a
Etienne Q, Lebrun V, Komuta M, Navez B, Thissen J, Leclercq I, et al. Fetuin-A in Activated Liver Macrophages Is a Key Feature of Non-Alcoholic Steatohepatitis. Metabolites. 2022;12: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 1e
Hoste E, Lecomte K, Annusver K, Vandamme N, Roels J, Maschalidi S, et al. OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity. Nat Commun. 2021;12:5913 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 7a
Huang Z, Liu S, Tang A, Al Rabadi L, Henkemeyer M, Mimche P, et al. Key role for EphB2 receptor in kidney fibrosis. Clin Sci (Lond). 2021;135:2127-2142 pubmed publisher
  • immunohistochemistry; mouse; 1:250; loading ...; fig 5c
Bruno K, Macomb L, Morales Lara A, Mathews J, Frisancho J, Yang A, et al. Sex-Specific Effects of Plastic Caging in Murine Viral Myocarditis. Int J Mol Sci. 2021;22: pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 7c
Jungwirth U, van Weverwijk A, Evans R, Jenkins L, Vicente D, Alexander J, et al. Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis. Nat Commun. 2021;12:3516 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a, s2b
Brownlie D, Doughty Shenton D, Yh Soong D, Nixon C, O Carragher N, M Carlin L, et al. Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β. J Immunother Cancer. 2021;9: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 3a
Jin X, Morro B, Tørresen O, Moiche V, Solbakken M, Jakobsen K, et al. Innovation in Nucleotide-Binding Oligomerization-Like Receptor and Toll-Like Receptor Sensing Drives the Major Histocompatibility Complex-II Free Atlantic Cod Immune System. Front Immunol. 2020;11:609456 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3c
Li Z, Murakoshi M, Ichikawa S, Koshida T, Adachi E, Suzuki C, et al. The sodium-glucose cotransporter 2 inhibitor tofogliflozin prevents diabetic kidney disease progression in type 2 diabetic mice. FEBS Open Bio. 2020;10:2761-2770 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2a
Sorrentino C, Yin Z, Ciummo S, Lanuti P, Lu L, Marchisio M, et al. Targeting Interleukin(IL)-30/IL-27p28 signaling in cancer stem-like cells and host environment synergistically inhibits prostate cancer growth and improves survival. J Immunother Cancer. 2019;7:201 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s2a, s2b
Aarts S, Seijkens T, Kusters P, Van Tiel C, Reiche M, den Toom M, et al. Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis. J Pathol. 2019;247:471-480 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1b
Vogl T, Stratis A, Wixler V, Voller T, Thurainayagam S, Jorch S, et al. Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest. 2018;128:1852-1866 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 6h
Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, et al. Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun. 2018;9:75 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
A Gonzalez N, Quintana J, Garcia Silva S, Mazariegos M, González de la Aleja A, Nicolás Ávila J, et al. Phagocytosis imprints heterogeneity in tissue-resident macrophages. J Exp Med. 2017;214:1281-1296 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 3b
Nicolas N, Michel V, Bhushan S, Wahle E, Hayward S, Ludlow H, et al. Testicular activin and follistatin levels are elevated during the course of experimental autoimmune epididymo-orchitis in mice. Sci Rep. 2017;7:42391 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1j
Halbrook C, Wen H, Ruggeri J, Takeuchi K, Zhang Y, di Magliano M, et al. Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis. Cell Mol Gastroenterol Hepatol. 2017;3:99-118 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig s1c
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar -, et al. DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas. Cell. 2016;167:1264-1280.e18 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig S7A
Troegeler A, Mercier I, Cougoule C, Pietretti D, Colom A, Duval C, et al. C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells. Proc Natl Acad Sci U S A. 2017;114:E540-E549 pubmed publisher
  • immunohistochemistry; mouse; 1:50; fig s1g
Jerić I, Maurer G, Cavallo A, Raguz J, Desideri E, Tarkowski B, et al. A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis. Nat Commun. 2016;7:13781 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 6a
Naeem A, Tommasi C, Cole C, Brown S, Zhu Y, Way B, et al. A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d. J Allergy Clin Immunol. 2017;139:1228-1241 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 8a
Lajko M, Cardona H, Taylor J, Shah R, Farrow K, Fawzi A. Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption. PLoS ONE. 2016;11:e0166886 pubmed publisher
  • immunohistochemistry; mouse; fig 1
Lin J, Kumari S, Kim C, Van T, Wachsmuth L, Polykratis A, et al. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature. 2016;540:124-128 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5a
Rudemiller N, Patel M, Zhang J, Jeffs A, Karlovich N, Griffiths R, et al. C-C Motif Chemokine 5 Attenuates Angiotensin II-Dependent Kidney Injury by Limiting Renal Macrophage Infiltration. Am J Pathol. 2016;186:2846-2856 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s2
Fransén Pettersson N, Duarte N, Nilsson J, Lundholm M, Mayans S, Larefalk A, et al. A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis. PLoS ONE. 2016;11:e0159850 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 5
Tsuboki J, Fujiwara Y, Horlad H, Shiraishi D, Nohara T, Tayama S, et al. Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages. Sci Rep. 2016;6:29588 pubmed publisher
  • flow cytometry; mouse; fig s3
Brandstätter O, Schanz O, Vorac J, König J, Mori T, Maruyama T, et al. Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor. Sci Rep. 2016;6:26091 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 2
Rubio Navarro A, Carril M, Padro D, Guerrero Hue M, Tarin C, Samaniego R, et al. CD163-Macrophages Are Involved in Rhabdomyolysis-Induced Kidney Injury and May Be Detected by MRI with Targeted Gold-Coated Iron Oxide Nanoparticles. Theranostics. 2016;6:896-914 pubmed publisher
  • immunohistochemistry; human; fig 1
Yang Y, Andersson P, Hosaka K, Zhang Y, Cao R, Iwamoto H, et al. The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages. Nat Commun. 2016;7:11385 pubmed publisher
  • immunohistochemistry; mouse; fig s4
Liu C, Rajapakse A, Riedo E, Fellay B, Bernhard M, Montani J, et al. Targeting arginase-II protects mice from high-fat-diet-induced hepatic steatosis through suppression of macrophage inflammation. Sci Rep. 2016;6:20405 pubmed publisher
  • immunohistochemistry; mouse; fig 1
Hirasawa M, Takubo K, Osada H, Miyake S, Toda E, Endo M, et al. Angiopoietin-like Protein 2 Is a Multistep Regulator of Inflammatory Neovascularization in a Murine Model of Age-related Macular Degeneration. J Biol Chem. 2016;291:7373-85 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran N, Aiolfi R, et al. IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. EMBO Mol Med. 2016;8:155-70 pubmed publisher
  • flow cytometry; mouse; loading ...
Leiva M, Quintana J, Ligos J, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;7:10222 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 4a
Ni Y, Nagashimada M, Zhuge F, Zhan L, Nagata N, Tsutsui A, et al. Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. Sci Rep. 2015;5:17192 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5a
Baba I, Egi Y, Utsumi H, Kakimoto T, Suzuki K. Inhibitory effects of fasudil on renal interstitial fibrosis induced by unilateral ureteral obstruction. Mol Med Rep. 2015;12:8010-20 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig s4
Pearson H, McGlinn E, Phesse T, Schlüter H, Srikumar A, Gödde N, et al. The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis. Mol Cancer. 2015;14:169 pubmed publisher
  • immunocytochemistry; mouse; 1:500; fig 5
  • immunohistochemistry; mouse; 1:500; fig 4
Nakamura R, Sene A, Santeford A, Gdoura A, Kubota S, Zapata N, et al. IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis. Nat Commun. 2015;6:7847 pubmed publisher
  • flow cytometry; mouse
Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, et al. DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance. Immunity. 2015;42:1143-58 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50
Vinue A, Andrés Blasco I, Herrero Cervera A, Piqueras L, Andres V, Burks D, et al. Ink4/Arf locus restores glucose tolerance and insulin sensitivity by reducing hepatic steatosis and inflammation in mice with impaired IRS2-dependent signalling. Biochim Biophys Acta. 2015;1852:1729-42 pubmed publisher
  • immunohistochemistry; mouse; 1:80; loading ...; fig s3a
Grabner B, Schramek D, Mueller K, Moll H, Svinka J, Hoffmann T, et al. Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis. Nat Commun. 2015;6:6285 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; fig s8
Zhu B, Chen Y, Zhang H, Liu X, Guo S. Resveratrol Reduces Myometrial Infiltration, Uterine Hyperactivity, and Stress Levels and Alleviates Generalized Hyperalgesia in Mice With Induced Adenomyosis. Reprod Sci. 2015;22:1336-49 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; tbl 1
Crncec I, Pathria P, Svinka J, Eferl R. Induction of colorectal cancer in mice and histomorphometric evaluation of tumors. Methods Mol Biol. 2015;1267:145-64 pubmed publisher
  • flow cytometry; human
Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, et al. Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection. J Immunol. 2015;194:1819-31 pubmed publisher
  • flow cytometry; mouse; fig s1
Evrard M, Chong S, Devi S, Chew W, Lee B, Poidinger M, et al. Visualization of bone marrow monocyte mobilization using Cx3cr1gfp/+Flt3L-/- reporter mouse by multiphoton intravital microscopy. J Leukoc Biol. 2015;97:611-9 pubmed publisher
  • immunohistochemistry; mouse; fig 1
Taniguchi T, Asano Y, Akamata K, Noda S, Takahashi T, Ichimura Y, et al. Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient mice. Arthritis Rheumatol. 2015;67:517-26 pubmed publisher
  • immunohistochemistry - frozen section; mouse
  • flow cytometry; mouse
Liu G, Zhang W, Xiao Y, Lu P. Critical Role of IP-10 on Reducing Experimental Corneal Neovascularization. Curr Eye Res. 2015;40:891-901 pubmed publisher
  • flow cytometry; mouse
Döring M, Lessin I, Frenz T, Spanier J, Kessler A, Tegtmeyer P, et al. M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells. J Virol. 2014;88:13638-50 pubmed publisher
  • flow cytometry; mouse
Bernasconi E, D Angelo F, Michetti P, Velin D. Critical role of the GM-CSF signaling pathway in macrophage pro-repair activities. Pathobiology. 2014;81:183-9 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500
de Bock L, Somers K, Fraussen J, Hendriks J, van Horssen J, Rouwette M, et al. Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis. J Immunol. 2014;193:2147-56 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200
Watatani H, Maeshima Y, Hinamoto N, Yamasaki H, Ujike H, Tanabe K, et al. Vasohibin-1 deficiency enhances renal fibrosis and inflammation after unilateral ureteral obstruction. Physiol Rep. 2014;2: pubmed publisher
  • immunohistochemistry - frozen section; mouse
Aytekin M, Tonelli A, Farver C, Feldstein A, Dweik R. Leptin deficiency recapitulates the histological features of pulmonary arterial hypertension in mice. Int J Clin Exp Pathol. 2014;7:1935-46 pubmed
  • immunohistochemistry - frozen section; mouse; 1:400
Gow D, Sauter K, Pridans C, Moffat L, Sehgal A, Stutchfield B, et al. Characterisation of a novel Fc conjugate of macrophage colony-stimulating factor. Mol Ther. 2014;22:1580-92 pubmed publisher
  • flow cytometry; mouse
Forgèt M, Voorhees J, Cole S, Dakhlallah D, Patterson I, Gross A, et al. Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer. PLoS ONE. 2014;9:e98623 pubmed publisher
  • immunohistochemistry; mouse
Wang J, Eguchi K, Matsumoto S, Fujiu K, Komuro I, Nagai R, et al. The ?-3 polyunsaturated fatty acid, eicosapentaenoic acid, attenuates abdominal aortic aneurysm development via suppression of tissue remodeling. PLoS ONE. 2014;9:e96286 pubmed publisher
  • immunohistochemistry; mouse
Ballak D, van Essen P, van Diepen J, Jansen H, Hijmans A, Matsuguchi T, et al. MAP3K8 (TPL2/COT) affects obesity-induced adipose tissue inflammation without systemic effects in humans and in mice. PLoS ONE. 2014;9:e89615 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50
Orim F, Bychkov A, Shimamura M, Nakashima M, Ito M, Matsuse M, et al. Thyrotropin signaling confers more aggressive features with higher genomic instability on BRAF(V600E)-induced thyroid tumors in a mouse model. Thyroid. 2014;24:502-10 pubmed publisher
  • immunocytochemistry; mouse
Ming X, Rajapakse A, Yepuri G, Xiong Y, Carvas J, Ruffieux J, et al. Arginase II Promotes Macrophage Inflammatory Responses Through Mitochondrial Reactive Oxygen Species, Contributing to Insulin Resistance and Atherogenesis. J Am Heart Assoc. 2012;1:e000992 pubmed publisher
Verboom L, Anderson C, Jans M, Petta I, Blancke G, Martens A, et al. OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection. Cell Death Dis. 2023;14:534 pubmed publisher
Sugita J, Fujiu K, Nakayama Y, Matsubara T, Matsuda J, Oshima T, et al. Cardiac macrophages prevent sudden death during heart stress. Nat Commun. 2021;12:1910 pubmed publisher
Cui C, Driscoll R, Piao Y, Chia C, Gorospe M, Ferrucci L. Skewed macrophage polarization in aging skeletal muscle. Aging Cell. 2019;18:e13032 pubmed publisher
Rojo R, Raper A, Ozdemir D, Lefèvre L, Grabert K, Wollscheid Lengeling E, et al. Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations. Nat Commun. 2019;10:3215 pubmed publisher
Phillips E, Lorch A, Durkes A, Goergen C. Early pathological characterization of murine dissecting abdominal aortic aneurysms. APL Bioeng. 2018;2:046106 pubmed publisher
Bond L, Burhans M, Ntambi J. Uncoupling protein-1 deficiency promotes brown adipose tissue inflammation and ER stress. PLoS ONE. 2018;13:e0205726 pubmed publisher
Bemiller S, Maphis N, Formica S, Wilson G, Miller C, Xu G, et al. Genetically enhancing the expression of chemokine domain of CX3CL1 fails to prevent tau pathology in mouse models of tauopathy. J Neuroinflammation. 2018;15:278 pubmed publisher
Mittenbühler M, Sprenger H, Gruber S, Wunderlich C, Kern L, Bruning J, et al. Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma. Mol Metab. 2018;17:122-133 pubmed publisher
Gresnigt M, Cunha C, Jaeger M, Gonçalves S, Malireddi R, Ammerdorffer A, et al. Genetic deficiency of NOD2 confers resistance to invasive aspergillosis. Nat Commun. 2018;9:2636 pubmed publisher
Kortlever R, Sodir N, Wilson C, Burkhart D, Pellegrinet L, Brown Swigart L, et al. Myc Cooperates with Ras by Programming Inflammation and Immune Suppression. Cell. 2017;171:1301-1315.e14 pubmed publisher
Kopec A, Abrahams S, Thornton S, Palumbo J, Mullins E, Divanovic S, et al. Thrombin promotes diet-induced obesity through fibrin-driven inflammation. J Clin Invest. 2017;127:3152-3166 pubmed publisher
Luo M, Flood E, Almeida D, Yan L, Berlin D, Heerdt P, et al. Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases. J Exp Med. 2017;214:2535-2545 pubmed publisher
Kongphat W, Pudgerd A, Sridurongrit S. Hepatocyte-specific expression of constitutively active Alk5 exacerbates thioacetamide-induced liver injury in mice. Heliyon. 2017;3:e00305 pubmed publisher
Furuya F, Ishii T, Tamura S, Takahashi K, Kobayashi H, Ichijo M, et al. The ligand-bound thyroid hormone receptor in macrophages ameliorates kidney injury via inhibition of nuclear factor-κB activities. Sci Rep. 2017;7:43960 pubmed publisher
Delire B, Lebrun V, Selvais C, Henriet P, Bertrand A, Horsmans Y, et al. Aging enhances liver fibrotic response in mice through hampering extracellular matrix remodeling. Aging (Albany NY). 2016;9:98-113 pubmed publisher
Cruz F, Horta L, Maia L, Lopes Pacheco M, da Silva A, Morales M, et al. Dasatinib Reduces Lung Inflammation and Fibrosis in Acute Experimental Silicosis. PLoS ONE. 2016;11:e0147005 pubmed publisher
Davies E, Dong M, Gutekunst M, Närhi K, van Zoggel H, Blom S, et al. Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices. Sci Rep. 2015;5:17187 pubmed publisher
Hood D, Moxon R, Purnell T, Richter C, Williams D, Azar A, et al. A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse. Dis Model Mech. 2016;9:69-79 pubmed publisher
Kim M, Piaia A, Shenoy N, Kagan D, Gapp B, Kueng B, et al. Progression of Alport Kidney Disease in Col4a3 Knock Out Mice Is Independent of Sex or Macrophage Depletion by Clodronate Treatment. PLoS ONE. 2015;10:e0141231 pubmed publisher
Hattori Y, Kim H, Tsuboi N, Yamamoto A, Akiyama S, Shi Y, et al. Therapeutic Potential of Stem Cells from Human Exfoliated Deciduous Teeth in Models of Acute Kidney Injury. PLoS ONE. 2015;10:e0140121 pubmed publisher
Guest I, Sell S. Bronchial lesions of mouse model of asthma are preceded by immune complex vasculitis and induced bronchial associated lymphoid tissue (iBALT). Lab Invest. 2015;95:886-902 pubmed publisher
Satpathy S, Jala V, Bodduluri S, Krishnan E, Hegde B, Hoyle G, et al. Crystalline silica-induced leukotriene B4-dependent inflammation promotes lung tumour growth. Nat Commun. 2015;6:7064 pubmed publisher
Simon Santamaria J, Rinaldo C, Kardas P, Li R, Malovic I, Elvevold K, et al. Efficient uptake of blood-borne BK and JC polyomavirus-like particles in endothelial cells of liver sinusoids and renal vasa recta. PLoS ONE. 2014;9:e111762 pubmed publisher
McCartney Francis N, Jin W, Belkaid Y, McGrady G, Wahl S. Aberrant host defense against Leishmania major in the absence of SLPI. J Leukoc Biol. 2014;96:917-29 pubmed publisher
Mehner C, Miller E, Khauv D, Nassar A, Oberg A, Bamlet W, et al. Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma. Mol Cancer Res. 2014;12:1430-9 pubmed publisher
Chen Y, Zhu B, Zhang H, Ding D, Liu X, Guo S. Possible Loss of GABAergic Inhibition in Mice With Induced Adenomyosis and Treatment With Epigallocatechin-3-Gallate Attenuates the Loss With Improved Hyperalgesia. Reprod Sci. 2014;21:869-882 pubmed
Bhaskar K, Maphis N, Xu G, Varvel N, Kokiko Cochran O, Weick J, et al. Microglial derived tumor necrosis factor-? drives Alzheimer's disease-related neuronal cell cycle events. Neurobiol Dis. 2014;62:273-85 pubmed publisher
Ferreira T, de Arantes A, do Nascimento C, Olsen P, Trentin P, Rocco P, et al. IL-13 immunotoxin accelerates resolution of lung pathological changes triggered by silica particles in mice. J Immunol. 2013;191:5220-9 pubmed publisher
Cargnoni A, Piccinelli E, Ressel L, Rossi D, Magatti M, Toschi I, et al. Conditioned medium from amniotic membrane-derived cells prevents lung fibrosis and preserves blood gas exchanges in bleomycin-injured mice-specificity of the effects and insights into possible mechanisms. Cytotherapy. 2014;16:17-32 pubmed publisher
Hemmeryckx B, Hoylaerts M, Deloose E, Van Hove C, Fransen P, Bult H, et al. Age-associated pro-inflammatory adaptations of the mouse thoracic aorta. Thromb Haemost. 2013;110:785-94 pubmed publisher
Cullen J, Faiola B, Melich D, Peterson R, Jordan H, Kimbrough C, et al. Effects of Kupffer cell depletion on acute alpha-naphthylisothiocyanate-induced liver toxicity in male mice. Toxicol Pathol. 2013;41:7-17 pubmed publisher
Camelo S, Raoul W, Lavalette S, Calippe B, Cristofaro B, Levy O, et al. Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages. Angiogenesis. 2012;15:609-22 pubmed publisher
Shchors K, Nozawa H, Xu J, Rostker F, Swigart Brown L, Evan G, et al. Increased invasiveness of MMP-9-deficient tumors in two mouse models of neuroendocrine tumorigenesis. Oncogene. 2013;32:502-13 pubmed publisher
Fuster J, Molina Sánchez P, Jovaní D, Vinue A, Serrano M, Andres V. Increased gene dosage of the Ink4/Arf locus does not attenuate atherosclerosis development in hypercholesterolaemic mice. Atherosclerosis. 2012;221:98-105 pubmed publisher
Deiuliis J, Kampfrath T, Zhong J, Oghumu S, Maiseyeu A, Chen L, et al. Pulmonary T cell activation in response to chronic particulate air pollution. Am J Physiol Lung Cell Mol Physiol. 2012;302:L399-409 pubmed publisher
Bobko A, Eubank T, Voorhees J, Efimova O, Kirilyuk I, Petryakov S, et al. In vivo monitoring of pH, redox status, and glutathione using L-band EPR for assessment of therapeutic effectiveness in solid tumors. Magn Reson Med. 2012;67:1827-36 pubmed publisher
Anania M, Sensi M, Radaelli E, Miranda C, Vizioli M, Pagliardini S, et al. TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells. Oncogene. 2011;30:3011-23 pubmed publisher
Peters T, Potter R, Li X, He Z, Hoskins G, Flessner M. Mouse model of foreign body reaction that alters the submesothelium and transperitoneal transport. Am J Physiol Renal Physiol. 2011;300:F283-9 pubmed publisher
Heindryckx F, Mertens K, Charette N, Vandeghinste B, Casteleyn C, Van Steenkiste C, et al. Kinetics of angiogenic changes in a new mouse model for hepatocellular carcinoma. Mol Cancer. 2010;9:219 pubmed publisher
Bottoms S, Howell J, Reinhardt A, Evans I, McAnulty R. Tgf-Beta isoform specific regulation of airway inflammation and remodelling in a murine model of asthma. PLoS ONE. 2010;5:e9674 pubmed publisher
Crowley S, Song Y, Sprung G, Griffiths R, Sparks M, Yan M, et al. A role for angiotensin II type 1 receptors on bone marrow-derived cells in the pathogenesis of angiotensin II-dependent hypertension. Hypertension. 2010;55:99-108 pubmed publisher
Musteanu M, Blaas L, Mair M, Schlederer M, Bilban M, Tauber S, et al. Stat3 is a negative regulator of intestinal tumor progression in Apc(Min) mice. Gastroenterology. 2010;138:1003-11.e1-5 pubmed publisher
Pazolli E, Luo X, Brehm S, Carbery K, Chung J, Prior J, et al. Senescent stromal-derived osteopontin promotes preneoplastic cell growth. Cancer Res. 2009;69:1230-9 pubmed publisher
Ibe S, Qin Z, Schuler T, Preiss S, Blankenstein T. Tumor rejection by disturbing tumor stroma cell interactions. J Exp Med. 2001;194:1549-59 pubmed
image
image 1 :
Bio-Rad MCA497G image 1
Dot Blot showing FSC/SSC gated mouse peritoneal macrophages dual stained with F4/80 ( MCA497A647 ) at a 1/5 dilution and CD11b ( MCA74F ) at a 1/5 dilution. Isotype control pair in red. Fc receptors were blocked by Mouse Seroblock ( BUF041B )
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA497G
Description :
Rat anti Mouse F4/80
Specificity :
F4/80
TargetSpecies :
Mouse
Host :
Rat
Format :
Purified
Isotypes :
IgG2b
Applications :
F,WB,C,P,IP,IF,R,RE,EM
ApplicationTypes :
Flow Cytometry,Western Blotting,Immunohistology - Frozen,Immunohistology - Paraffin,Immunoprecipitation,Immunofluorescence,Radioimmunoassays,Immunohistology - Resin,Immuno-electron Microscopy
Clone :
Cl:A3-1
Quantity :
0.5 mg
Quantity Value :
0.5
Quantity Type :
mg
GO Accessions :
GO:0005509,GO:0016021,GO:0004930,GO:0007218,GO:0009897
GOTerms :
calcium ion binding,integral to membrane,G-protein coupled receptor activity,neuropeptide signaling pathway,external side of plasma membrane
Uniprot Accessions :
Q61549
Gene :
Emr1
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=13733
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,APC,Biotin,FITC,Low Endotoxin,Pacific Blue®,Purified,RPE,S/N,Alexa Fluor® 700,StarBright Blue 700,Amethyst Orange,StarBright Violet 440,StarBright Violet 515,StarBright Violet 610,StarBright Violet 670,StarBright Violet 570,StarBright Violet 710,StarBright Violet 790,StarBright Violet 475,StarBright UltraViolet 400,StarBright UltraViolet 665,StarBright UltraViolet 795,StarBright Violet 760,StarBright UltraViolet 445,StarBright UltraViolet 510,StarBright UltraViolet 740,StarBright UltraViolet 575,StarBright UltraViolet 605,StarBright Blue 580,StarBright Blue 615,StarBright Blue 675,StarBright Blue 765,StarBright Blue 810,StarBright Yellow 575,StarBright Yellow 605,StarBright Yellow 665,StarBright Yellow 800,StarBright Yellow 720,StarBright Red 670,StarBright Red 715,StarBright Red 775,StarBright Red 815
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
382
PriceEUR :
542
PriceUSD :
618 USD
PriceCHF :
590
PriceSEK :
6179
PriceNOK :
6170
PriceDKK :
4043
more info or order :
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.