product summary
Loading...
company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Mouse F4/80:Alexa Fluor® 647
catalog :
MCA497A647
quantity :
100 Tests/1 ml
price :
404 USD
clonality :
monoclonal
host :
rat
conjugate :
AF647
clone name :
Cl:A3-1
reactivity :
human, mouse
application :
flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Bio-Rad product webpage
citations: 13
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:100; loading ...; fig s1b
Jungwirth U, van Weverwijk A, Evans R, Jenkins L, Vicente D, Alexander J, et al. Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis. Nat Commun. 2021;12:3516 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig s1c
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar -, et al. DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas. Cell. 2016;167:1264-1280.e18 pubmed publisher
  • flow cytometry; mouse; loading ...
Saha S, Aranda E, Hayakawa Y, Bhanja P, Atay S, Brodin N, et al. Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury. Nat Commun. 2016;7:13096 pubmed publisher
  • flow cytometry; mouse; loading ...; fig st2
Rantakari P, Jäppinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, et al. Fetal liver endothelium regulates the seeding of tissue-resident macrophages. Nature. 2016;538:392-396 pubmed publisher
  • flow cytometry; mouse; fig s3b
Ohmer M, Weber A, Sutter G, Ehrhardt K, Zimmermann A, Häcker G. Anti-apoptotic Bcl-XL but not Mcl-1 contributes to protection against virus-induced apoptosis. Cell Death Dis. 2016;7:e2340 pubmed publisher
  • flow cytometry; mouse; 1:200; fig s3
Hollmen M, Karaman S, Schwager S, Lisibach A, Christiansen A, Maksimow M, et al. G-CSF regulates macrophage phenotype and associates with poor overall survival in human triple-negative breast cancer. Oncoimmunology. 2016;5:e1115177 pubmed
  • flow cytometry; mouse; loading ...
Leiva M, Quintana J, Ligos J, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;7:10222 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Mu X, Español Suñer R, Mederacke I, Affò S, Manco R, Sempoux C, et al. Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment. J Clin Invest. 2015;125:3891-903 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3
Vi L, Baht G, Whetstone H, Ng A, Wei Q, Poon R, et al. Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis. J Bone Miner Res. 2015;30:1090-102 pubmed publisher
  • immunohistochemistry - frozen section; human
Hayes B, Riehle K, Shimizu Albergine M, Bauer R, Hudkins K, Johansson F, et al. Activation of platelet-derived growth factor receptor alpha contributes to liver fibrosis. PLoS ONE. 2014;9:e92925 pubmed publisher
Pello O, Chevre R, Laoui D, De Juan A, Lolo F, Andrés Manzano M, et al. In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities. PLoS ONE. 2012;7:e45399 pubmed publisher
Moussaud S, Draheim H. A new method to isolate microglia from adult mice and culture them for an extended period of time. J Neurosci Methods. 2010;187:243-53 pubmed publisher
Kim H, Kim I. Transforming growth factor-beta-induced gene product, as a novel ligand of integrin alphaMbeta2, promotes monocytes adhesion, migration and chemotaxis. Int J Biochem Cell Biol. 2008;40:991-1004 pubmed
image
image 1 :
Bio-Rad MCA497A647 image 1
Dot Blot showing FSC/SSC gated mouse peritoneal macrophages dual stained with F4/80 ( MCA497A647 ) at a 1/5 dilution and CD11b ( MCA74F ) at a 1/5 dilution. Isotype control pair in red. Fc receptors were blocked by Mouse Seroblock ( BUF041B )
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA497A647
Description :
Rat anti Mouse F4/80:Alexa Fluor® 647
Specificity :
F4/80
TargetSpecies :
Mouse
Host :
Rat
Format :
Alexa Fluor® 647
Conjugate/Tag :
Alexa Fluor® 647
Isotypes :
IgG2b
Applications :
F
ApplicationTypes :
Flow Cytometry
Clone :
Cl:A3-1
Quantity :
100 Tests/1 ml
Quantity Value :
100
Quantity Type :
Tests/1ml
GO Accessions :
GO:0005509,GO:0016021,GO:0004930,GO:0007218,GO:0009897
GOTerms :
calcium ion binding,integral to membrane,G-protein coupled receptor activity,neuropeptide signaling pathway,external side of plasma membrane
Uniprot Accessions :
Q61549
Gene :
Emr1
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=13733
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,APC,Biotin,FITC,Low Endotoxin,Pacific Blue®,Purified,RPE,S/N,Alexa Fluor® 700,StarBright Blue 700,Amethyst Orange,StarBright Violet 440,StarBright Violet 515,StarBright Violet 610,StarBright Violet 670,StarBright Violet 570,StarBright Violet 710,StarBright Violet 790,StarBright Violet 475,StarBright UltraViolet 400,StarBright UltraViolet 665,StarBright UltraViolet 795,StarBright Violet 760,StarBright UltraViolet 445,StarBright UltraViolet 510,StarBright UltraViolet 740,StarBright UltraViolet 575,StarBright UltraViolet 605,StarBright Blue 580,StarBright Blue 615,StarBright Blue 675,StarBright Blue 765,StarBright Blue 810,StarBright Yellow 575,StarBright Yellow 605,StarBright Yellow 665,StarBright Yellow 800,StarBright Yellow 720,StarBright Red 670,StarBright Red 715,StarBright Red 775,StarBright Red 815
UNSPSC :
41116161
Concentration :
IgG concentration 0.05 mg/ml
Product Form :
Purified IgG conjugated to Alexa Fluor® 647 - liquid
PriceGBP :
289
PriceEUR :
404
PriceUSD :
404 USD
PriceCHF :
439
PriceSEK :
4606
PriceNOK :
4599
PriceDKK :
3013
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.