product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Mouse F4/80:Alexa Fluor® 488
catalog :
MCA497A488
quantity :
100 Tests/1 ml
price :
428 USD
clonality :
monoclonal
host :
rat
conjugate :
AF488
clone name :
Cl:A3-1
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
Bio-Rad product webpage
citations: 12
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 5:200; loading ...; fig 6a
  • immunocytochemistry; mouse; 5:200; loading ...; fig 8a
Horsthemke M, Bachg A, Groll K, Moyzio S, Müther B, Hemkemeyer S, et al. Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion. J Biol Chem. 2017;292:7258-7273 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 4b
Comunanza V, Cora D, Orso F, Consonni F, Middonti E, Di Nicolantonio F, et al. VEGF blockade enhances the antitumor effect of BRAFV600E inhibition. EMBO Mol Med. 2017;9:219-237 pubmed publisher
  • immunocytochemistry; mouse; 1:150
Wong H, Jin G, Cao R, Zhang S, Cao Y, Zhou Z. MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis. Nat Commun. 2016;7:10824 pubmed publisher
  • flow cytometry; mouse; 1:50; fig 4
Li M, Li M, Yin T, Shi H, Wen Y, Zhang B, et al. Targeting of cancer‑associated fibroblasts enhances the efficacy of cancer chemotherapy by regulating the tumor microenvironment. Mol Med Rep. 2016;13:2476-84 pubmed publisher
  • flow cytometry; mouse; fig 5
Eichin D, Laurila J, Jalkanen S, Salmi M. CD73 Activity is Dispensable for the Polarization of M2 Macrophages. PLoS ONE. 2015;10:e0134721 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100
Meraz I, Savage D, Segura Ibarra V, Li J, Rhudy J, Gu J, et al. Adjuvant cationic liposomes presenting MPL and IL-12 induce cell death, suppress tumor growth, and alter the cellular phenotype of tumors in a murine model of breast cancer. Mol Pharm. 2014;11:3484-91 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Meraz I, Hearnden C, Liu X, Yang M, Williams L, Savage D, et al. Multivalent presentation of MPL by porous silicon microparticles favors T helper 1 polarization enhancing the anti-tumor efficacy of doxorubicin nanoliposomes. PLoS ONE. 2014;9:e94703 pubmed publisher
Horsthemke M, Nutter L, Bachg A, Skryabin B, Honnert U, Zobel T, et al. A novel isoform of myosin 18A (Myo18Aγ) is an essential sarcomeric protein in mouse heart. J Biol Chem. 2019;294:7202-7218 pubmed publisher
Incio J, Suboj P, Chin S, Vardam Kaur T, Liu H, Hato T, et al. Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages. PLoS ONE. 2015;10:e0141392 pubmed publisher
Königs V, Jennings R, Vogl T, Horsthemke M, Bachg A, Xu Y, et al. Mouse macrophages completely lacking Rho subfamily GTPases (RhoA, RhoB, and RhoC) have severe lamellipodial retraction defects, but robust chemotactic navigation and altered motility. J Biol Chem. 2014;289:30772-84 pubmed publisher
Pello O, Chevre R, Laoui D, De Juan A, Lolo F, Andrés Manzano M, et al. In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities. PLoS ONE. 2012;7:e45399 pubmed publisher
Hanley P, Kronlage M, Kirschning C, del Rey A, Di Virgilio F, Leipziger J, et al. Transient P2X7 receptor activation triggers macrophage death independent of Toll-like receptors 2 and 4, caspase-1, and pannexin-1 proteins. J Biol Chem. 2012;287:10650-63 pubmed publisher
product information
EntityType :
Monoclonal Antibody
EntityCategory :
Antibodies
ProductCode :
MCA497A488
Description :
Rat anti Mouse F4/80:Alexa Fluor® 488
Specificity :
F4/80
TargetSpecies :
Mouse
Host :
Rat
Format :
Alexa Fluor® 488
Conjugate/Tag :
Alexa Fluor® 488
Isotypes :
IgG2b
Applications :
F
ApplicationTypes :
Flow Cytometry
Clone :
Cl:A3-1
Quantity :
100 Tests/1 ml
QuantityValue :
100
QuantityType :
Tests/1ml
GOAccessions :
GO:0005509,GO:0016021,GO:0004930,GO:0007218,GO:0009897
GOTerms :
calcium ion binding,integral to membrane,G-protein coupled receptor activity,neuropeptide signaling pathway,external side of plasma membrane
UniprotAccessions :
Q61549
Gene :
Emr1
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=13733
EntityFormats :
Alexa Fluor® 488,Alexa Fluor® 647,APC,Biotin,FITC,Low Endotoxin,Pacific Blue®,Purified,RPE,S/N,Alexa Fluor® 700,StarBright Blue 700,StarBright Violet 440,StarBright Violet 515,StarBright Violet 610,StarBright Violet 670,StarBright Violet 570,StarBright Violet 710,StarBright Violet 790,StarBright Violet 475,StarBright UltraViolet 400,StarBright UltraViolet 665,StarBright UltraViolet 795,StarBright Violet 760,StarBright UltraViolet 445,StarBright UltraViolet 510,StarBright UltraViolet 740,StarBright UltraViolet 575,StarBright UltraViolet 605,StarBright Blue 580,StarBright Blue 615,StarBright Blue 675,StarBright Blue 765,StarBright Blue 810,StarBright Yellow 575,StarBright Yellow 605,StarBright Yellow 665,StarBright Yellow 800,StarBright Yellow 720,StarBright Red 670,StarBright Red 715,StarBright Red 775,StarBright Red 815,StarBright UltraViolet 540,StarBright UltraViolet 700,StarBright Violet 535
UNSPSC :
41116161
Concentration :
IgG concentration 0.05 mg/ml
ProductForm :
Purified IgG conjugated to Alexa Fluor® 488 - liquid
PriceGBP :
299
PriceEUR :
418
PriceUSD :
428 USD
PriceCHF :
455
PriceSEK :
4661
PriceNOK :
4807
PriceDKK :
3118
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.