product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Rat CD8 Alpha
catalog :
MCA48G
quantity :
1 mg
price :
660 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OX-8
reactivity :
mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Bio-Rad product webpage
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat; 1:200; fig 1
Elgström E, Eriksson S, Ljungberg O, Bendahl P, Ohlsson T, Nilsson R, et al. Evaluation of immune cell markers in tumor tissue treated with radioimmunotherapy in an immunocompetent rat colon carcinoma model. EJNMMI Res. 2015;5:47 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100; fig 3
Safeukui I, Gómez N, Adelani A, Burté F, Afolabi N, Akondy R, et al. Malaria induces anemia through CD8+ T cell-dependent parasite clearance and erythrocyte removal in the spleen. MBio. 2015;6: pubmed publisher
  • flow cytometry; mouse; fig 8
Zschemisch N, Glage S, Wedekind D, Weinstein E, Cui X, Dorsch M, et al. Zinc-finger nuclease mediated disruption of Rag1 in the LEW/Ztm rat. BMC Immunol. 2012;13:60 pubmed publisher
Heuer A, Kirkeby A, Pfisterer U, Jönsson M, Parmar M. hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation. Exp Neurol. 2016;282:78-85 pubmed publisher
Puntel M, A K M G, Farrokhi C, Vanderveen N, Paran C, Appelhans A, et al. Safety profile, efficacy, and biodistribution of a bicistronic high-capacity adenovirus vector encoding a combined immunostimulation and cytotoxic gene therapy as a prelude to a phase I clinical trial for glioblastoma. Toxicol Appl Pharmacol. 2013;268:318-30 pubmed publisher
Candolfi M, King G, Yagiz K, Curtin J, Mineharu Y, Muhammad A, et al. Plasmacytoid dendritic cells in the tumor microenvironment: immune targets for glioma therapeutics. Neoplasia. 2012;14:757-70 pubmed
Muhammad A, Xiong W, Puntel M, Farrokhi C, Kroeger K, Salem A, et al. Safety profile of gutless adenovirus vectors delivered into the normal brain parenchyma: implications for a glioma phase 1 clinical trial. Hum Gene Ther Methods. 2012;23:271-84 pubmed publisher
King G, Muhammad A, Larocque D, Kelson K, Xiong W, Liu C, et al. Combined Flt3L/TK gene therapy induces immunological surveillance which mediates an immune response against a surrogate brain tumor neoantigen. Mol Ther. 2011;19:1793-801 pubmed publisher
Khan S, Pham S, Wei Y, Mateo D, St Pierre M, Fletcher T, et al. Stress-induced senescence exaggerates postinjury neointimal formation in the old vasculature. Am J Physiol Heart Circ Physiol. 2010;298:H66-74 pubmed publisher
Borkamo E, Dahl O, Bruland O, Fluge O. Global gene expression analyses reveal changes in biological processes after hyperthermia in a rat glioma model. Int J Hyperthermia. 2008;24:425-41 pubmed publisher
Yin R, Huang H, Zhang J, Zhu J, Jing H, Li Z. Dietary n-3 fatty acids attenuate cardiac allograft vasculopathy via activating peroxisome proliferator-activated receptor-gamma. Pediatr Transplant. 2008;12:550-6 pubmed publisher
King G, Kroeger K, Bresee C, Candolfi M, Liu C, Manalo C, et al. Flt3L in combination with HSV1-TK-mediated gene therapy reverses brain tumor-induced behavioral deficits. Mol Ther. 2008;16:682-90 pubmed publisher
Yin R, Zhu J, Shao H, Cheng X, Feng X, Li Z, et al. Inhibition of chemokine receptor CCR2 and CCR5 expression contributes to simvastatin-induced attenuation of cardiac allograft vasculopathy. J Heart Lung Transplant. 2007;26:485-93 pubmed
Ma H, Wang J, Wang J, Li Y, Li J. Features of chronic allograft rejection on rat small intestine transplantation. Pediatr Transplant. 2007;11:165-72 pubmed
image
image 1 :
Bio-Rad MCA48G image 1
Figure A. Alexa Fluor 488 conjugated Mouse anti Rat CD4 ( MCA55A488 ) and Alexa Fluor 647 conjugated Mouse IgG1 isotype control ( MCA1209A647 ). Figure B. Alexa Fluor 488 conjugated Mouse anti Rat CD4 ( MCA55A488 ) and Alexa Fluor 647 conjugated Mouse anti Rat CD8 ( MCA48A647 ). All experiments performed on red cell lysed rat blood gated on lymphoid cells in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA48G
Description :
Mouse anti Rat CD8 Alpha
Specificity :
CD8 Alpha
TargetSpecies :
Rat
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
WB,P,IP,F,C,IF
ApplicationTypes :
Western Blotting,Immunohistology - Paraffin,Immunoprecipitation,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
Clone :
OX-8
Quantity :
1 mg
Quantity Value :
1
Quantity Type :
mg
GO Accessions :
GO:0016021,GO:0006954,GO:0019901
GOTerms :
integral to membrane,inflammatory response,protein kinase binding
Uniprot Accessions :
P07725
Gene :
Cd8a
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=24930
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,Purified,RPE,RPE-Alexa Fluor® 647
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
471
PriceEUR :
660
PriceUSD :
660 USD
PriceCHF :
718
PriceSEK :
7194
PriceNOK :
7230
PriceDKK :
4921
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.