product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Rat MHC Class II RT1B
catalog :
MCA46G
quantity :
1 mg
price :
680 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OX-6
reactivity :
rat
application :
immunocytochemistry, flow cytometry, immunohistochemistry - free floating section
more info or order :
Bio-Rad product webpage
citations: 20
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - free floating section; rat; 1:250; loading ...; fig 11a
Van der Perren A, Gelders G, Fenyi A, Bousset L, Brito F, Peelaerts W, et al. The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson's disease, multiple system atrophy and dementia with Lewy bodies. Acta Neuropathol. 2020;139:977-1000 pubmed publisher
  • flow cytometry; rat; fig s6e
Flach A, Litke T, Strauss J, Haberl M, Gómez C, Reindl M, et al. Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease. Proc Natl Acad Sci U S A. 2016;113:3323-8 pubmed publisher
Wimmer I, Scharler C, Zrzavy T, Kadowaki T, Mödlagl V, Rojc K, et al. Microglia pre-activation and neurodegeneration precipitate neuroinflammation without exacerbating tissue injury in experimental autoimmune encephalomyelitis. Acta Neuropathol Commun. 2019;7:14 pubmed publisher
Duffy M, Collier T, Patterson J, Kemp C, Luk K, TANSEY M, et al. Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration. J Neuroinflammation. 2018;15:129 pubmed publisher
Barreto G, Santos Galindo M, Garcia Segura L. Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury. Front Aging Neurosci. 2014;6:132 pubmed publisher
Puntel M, A K M G, Farrokhi C, Vanderveen N, Paran C, Appelhans A, et al. Safety profile, efficacy, and biodistribution of a bicistronic high-capacity adenovirus vector encoding a combined immunostimulation and cytotoxic gene therapy as a prelude to a phase I clinical trial for glioblastoma. Toxicol Appl Pharmacol. 2013;268:318-30 pubmed publisher
Prasad A, Xue Q, Sankar V, Nishida T, Shaw G, Streit W, et al. Comprehensive characterization and failure modes of tungsten microwire arrays in chronic neural implants. J Neural Eng. 2012;9:056015 pubmed
Muhammad A, Xiong W, Puntel M, Farrokhi C, Kroeger K, Salem A, et al. Safety profile of gutless adenovirus vectors delivered into the normal brain parenchyma: implications for a glioma phase 1 clinical trial. Hum Gene Ther Methods. 2012;23:271-84 pubmed publisher
Giatti S, Boraso M, Abbiati F, Ballarini E, Calabrese D, Santos Galindo M, et al. Multimodal analysis in acute and chronic experimental autoimmune encephalomyelitis. J Neuroimmune Pharmacol. 2013;8:238-50 pubmed publisher
Hinwood M, Tynan R, Charnley J, Beynon S, Day T, Walker F. Chronic stress induced remodeling of the prefrontal cortex: structural re-organization of microglia and the inhibitory effect of minocycline. Cereb Cortex. 2013;23:1784-97 pubmed publisher
Giatti S, Caruso D, Boraso M, Abbiati F, Ballarini E, Calabrese D, et al. Neuroprotective effects of progesterone in chronic experimental autoimmune encephalomyelitis. J Neuroendocrinol. 2012;24:851-61 pubmed publisher
Hinwood M, Morandini J, Day T, Walker F. Evidence that microglia mediate the neurobiological effects of chronic psychological stress on the medial prefrontal cortex. Cereb Cortex. 2012;22:1442-54 pubmed publisher
Walberer M, Rueger M, Simard M, Emig B, Jander S, Fink G, et al. Dynamics of neuroinflammation in the macrosphere model of arterio-arterial embolic focal ischemia: an approximation to human stroke patterns. Exp Transl Stroke Med. 2010;2:22 pubmed publisher
Almolda B, Gonzalez B, Castellano B. Activated microglial cells acquire an immature dendritic cell phenotype and may terminate the immune response in an acute model of EAE. J Neuroimmunol. 2010;223:39-54 pubmed publisher
Tapia Gonzalez S, Carrero P, Pernia O, Garcia Segura L, Diz Chaves Y. Selective oestrogen receptor (ER) modulators reduce microglia reactivity in vivo after peripheral inflammation: potential role of microglial ERs. J Endocrinol. 2008;198:219-30 pubmed publisher
King G, Kroeger K, Bresee C, Candolfi M, Liu C, Manalo C, et al. Flt3L in combination with HSV1-TK-mediated gene therapy reverses brain tumor-induced behavioral deficits. Mol Ther. 2008;16:682-90 pubmed publisher
Barreto G, Veiga S, Azcoitia I, Garcia Segura L, Garcia Ovejero D. Testosterone decreases reactive astroglia and reactive microglia after brain injury in male rats: role of its metabolites, oestradiol and dihydrotestosterone. Eur J Neurosci. 2007;25:3039-46 pubmed
Kawashima N, Suzuki N, Yang G, Ohi C, Okuhara S, Nakano Kawanishi H, et al. Kinetics of RANKL, RANK and OPG expressions in experimentally induced rat periapical lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103:707-11 pubmed
Stampachiacchiere B, Aloe L. Differential modulatory effect of NGF on MHC class I and class II expression in spinal cord cells of EAE rats. J Neuroimmunol. 2005;169:20-30 pubmed
Porporatto C, Bianco I, Correa S. Local and systemic activity of the polysaccharide chitosan at lymphoid tissues after oral administration. J Leukoc Biol. 2005;78:62-9 pubmed
image
image 1 :
Bio-Rad MCA46G image 1
Figure A. FITC conjugated Mouse anti Rat CD45RA ( MCA340FT ) and RPE conjugated Mouse IgG1 isotype control ( MCA1029PE ). Figure B. FITC conjugated Rat anti Mouse CD45RA ( MCA340FT ) and RPE conjugated Mouse anti Rat MHC-II (MCA46PE). All experiments performed on red cell lysed rat blood gated on lymphoid cells in the presence of 10% rat serum. Data acquired on the ZE5 Cell Analyzer.
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA46G
Description :
Mouse anti Rat MHC Class II RT1B
Specificity :
MHC Class II RT1B
TargetSpecies :
Rat
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
P,F,C,IF
ApplicationTypes :
Immunohistology - Paraffin,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
Cross Reactivities :
Mouse
Clone :
OX-6
Quantity :
1 mg
Quantity Value :
1
Quantity Type :
mg
Entity Formats :
Alexa Fluor® 647,FITC,Purified,RPE
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
486
PriceEUR :
680
PriceUSD :
680 USD
PriceCHF :
740
PriceSEK :
7752
PriceNOK :
7741
PriceDKK :
5072
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.