product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Rat CD68
catalog :
MCA341GA
quantity :
0.1 mg
price :
298 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
ED1
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
citations: 67
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 2f
Guo Y, Lu Y, Lu X, He S, Li S, Shao S, et al. Krüppel-Like Factor 15/Interleukin 11 Axis-Mediated Adventitial Remodeling Depends on Extracellular Signal-Regulated Kinases 1 and 2 Activation in Angiotensin II-Induced Hypertension. J Am Heart Assoc. 2021;10:e020554 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:500; loading ...; fig 2f
De Miranda B, Castro S, Rocha E, Bodle C, Johnson K, Greenamyre J. The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease. Neurobiol Dis. 2021;153:105312 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:200; loading ...; fig 3c
Zhang L, Pan J, Mamtilahun M, Zhu Y, Wang L, Venkatesh A, et al. Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion. Theranostics. 2020;10:74-90 pubmed publisher
  • immunohistochemistry; rat; loading ...; fig s3c
Lodygin D, Hermann M, Schweingruber N, Flügel Koch C, Watanabe T, Schlosser C, et al. β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration. Nature. 2019;566:503-508 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:500; loading ...; fig 5b, 5d, 6a, 7a, 7g
Pridans C, Raper A, Davis G, Alves J, Sauter K, Lefèvre L, et al. Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus. J Immunol. 2018;201:2683-2699 pubmed publisher
  • immunohistochemistry; rat; 1:200; loading ...; fig 8
Wang Y, Lin Y, Wu Y, Yao Z, Tang J, Shen L, et al. Expression and Cellular Localization of IFITM1 in Normal and Injured Rat Spinal Cords. J Histochem Cytochem. 2018;66:175-187 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:300
  • immunohistochemistry - paraffin section; rat; 1:100; loading ...; fig st4
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  • immunohistochemistry; rat; 1:100; loading ...; fig 9a
Ibañez Rodriguez M, Noctor S, Muñoz E. Cellular Basis of Pineal Gland Development: Emerging Role of Microglia as Phenotype Regulator. PLoS ONE. 2016;11:e0167063 pubmed publisher
  • immunohistochemistry; rat; 1:100; loading ...; fig 2a
Xie Y, Guo H, Wang L, Xu L, Zhang X, Yu L, et al. Human albumin attenuates excessive innate immunity via inhibition of microglial Mincle/Syk signaling in subarachnoid hemorrhage. Brain Behav Immun. 2017;60:346-360 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:200; fig 2
Xiong X, Gu L, Wang Y, Luo Y, Zhang H, Lee J, et al. Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms. J Neuroinflammation. 2016;13:241 pubmed publisher
  • immunohistochemistry; rat; 2.5 ug/ml; loading ...
  • western blot; rat; 1 ug/ml; fig 1b
Kawahara K, Hirata H, Ohbuchi K, Nishi K, Maeda A, Kuniyasu A, et al. The novel monoclonal antibody 9F5 reveals expression of a fragment of GPNMB/osteoactivin processed by furin-like protease(s) in a subpopulation of microglia in neonatal rat brain. Glia. 2016;64:1938-61 pubmed publisher
  • immunohistochemistry; mouse; 1:700; loading ...; fig 3
Stojakovic A, Paz Filho G, Arcos Burgos M, Licinio J, Wong M, Mastronardi C. Role of the IL-1 Pathway in Dopaminergic Neurodegeneration and Decreased Voluntary Movement. Mol Neurobiol. 2017;54:4486-4495 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:1000; fig 4
Backes H, Walberer M, Ladwig A, Rueger M, Neumaier B, Endepols H, et al. Glucose consumption of inflammatory cells masks metabolic deficits in the brain. Neuroimage. 2016;128:54-62 pubmed publisher
  • immunohistochemistry - paraffin section; rat; fig 5
Nozako M, Koyama T, Nagano C, Sato M, Matsumoto S, Mitani K, et al. An Atherogenic Paigen-Diet Aggravates Nephropathy in Type 2 Diabetic OLETF Rats. PLoS ONE. 2015;10:e0143979 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:200; fig 3
Elgström E, Eriksson S, Ljungberg O, Bendahl P, Ohlsson T, Nilsson R, et al. Evaluation of immune cell markers in tumor tissue treated with radioimmunotherapy in an immunocompetent rat colon carcinoma model. EJNMMI Res. 2015;5:47 pubmed publisher
  • flow cytometry; rat; 1:200; fig 2
Chen Y, Zhu H, Zhang N, Shen L, Wang R, Zhou J, et al. Temporal kinetics of macrophage polarization in the injured rat spinal cord. J Neurosci Res. 2015;93:1526-33 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:150; loading ...
Nacka Aleksić M, Djikić J, Pilipović I, Stojić Vukanić Z, Kosec D, Bufan B, et al. Male rats develop more severe experimental autoimmune encephalomyelitis than female rats: sexual dimorphism and diergism at the spinal cord level. Brain Behav Immun. 2015;49:101-18 pubmed publisher
  • flow cytometry; rat; fig 6
Haag S, Tuncel J, Thordardottir S, Mason D, Yau A, Dobritzsch D, et al. Positional identification of RT1-B (HLA-DQ) as susceptibility locus for autoimmune arthritis. J Immunol. 2015;194:2539-50 pubmed publisher
  • immunohistochemistry - paraffin section; rat; loading ...; fig 2e
Aharon Hananel G, Jörns A, Lenzen S, Raz I, Weksler Zangen S. Antidiabetic Effect of Interleukin-1β Antibody Therapy Through β-Cell Protection in the Cohen Diabetes-Sensitive Rat. Diabetes. 2015;64:1780-5 pubmed publisher
  • immunohistochemistry; rat; 1:100; loading ...; fig 6a
Mata K, Tefé Silva C, Floriano E, Fernandes C, Rizzi E, Gerlach R, et al. Interference of doxycycline pretreatment in a model of abdominal aortic aneurysms. Cardiovasc Pathol. 2015;24:110-20 pubmed publisher
  • immunohistochemistry; rat; 1:600; fig 2
He D, Kou X, Luo Q, Yang R, Liu D, Wang X, et al. Enhanced M1/M2 macrophage ratio promotes orthodontic root resorption. J Dent Res. 2015;94:129-39 pubmed publisher
  • immunohistochemistry; rat; 1:50
Schlaubitz S, Derkaoui S, Marosa L, Miraux S, Renard M, Catros S, et al. Pullulan/dextran/nHA macroporous composite beads for bone repair in a femoral condyle defect in rats. PLoS ONE. 2014;9:e110251 pubmed publisher
  • immunohistochemistry - paraffin section; rat; fig 1
Wang Y, Alexander S. DNA vaccination as a treatment for chronic kidney disease. Methods Mol Biol. 2014;1143:297-303 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:100
Prins M, Eriksson C, Wierinckx A, Bol J, Binnekade R, Tilders F, et al. Interleukin-1β and interleukin-1 receptor antagonist appear in grey matter additionally to white matter lesions during experimental multiple sclerosis. PLoS ONE. 2013;8:e83835 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:500
Tour G, Wendel M, Tcacencu I. Bone marrow stromal cells enhance the osteogenic properties of hydroxyapatite scaffolds by modulating the foreign body reaction. J Tissue Eng Regen Med. 2014;8:841-9 pubmed publisher
Chien J, Chou Y, Ciou J, Liu F, Huang S. The Effects of Two Nrf2 Activators, Bardoxolone Methyl and Omaveloxolone, on Retinal Ganglion Cell Survival during Ischemic Optic Neuropathy. Antioxidants (Basel). 2021;10: pubmed publisher
Novoyatleva T, Rai N, Kojonazarov B, Veeroju S, Ben Batalla I, Caruso P, et al. Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2. Commun Biol. 2021;4:1002 pubmed publisher
Goulao M, Ghosh B, Urban M, Sahu M, Mercogliano C, Charsar B, et al. Astrocyte progenitor transplantation promotes regeneration of bulbospinal respiratory axons, recovery of diaphragm function, and a reduced macrophage response following cervical spinal cord injury. Glia. 2019;67:452-466 pubmed publisher
Kühne L, Jung B, Poth H, Schuster A, Wurm S, Ruemmele P, et al. Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy. BMC Immunol. 2017;18:52 pubmed publisher
Mokarram N, Dymanus K, Srinivasan A, Lyon J, Tipton J, Chu J, et al. Immunoengineering nerve repair. Proc Natl Acad Sci U S A. 2017;114:E5077-E5084 pubmed publisher
Seemann S, Lupp A. Administration of AMD3100 in endotoxemia is associated with pro-inflammatory, pro-oxidative, and pro-apoptotic effects in vivo. J Biomed Sci. 2016;23:68 pubmed
Jung M, Brüne B, Hotter G, Sola A. Macrophage-derived Lipocalin-2 contributes to ischemic resistance mechanisms by protecting from renal injury. Sci Rep. 2016;6:21950 pubmed publisher
Ko Y, Tsai M, Chang R, Chang C, Wang C, Wu M, et al. Methylprednisolone Protects Cardiac Pumping Mechanics from Deteriorating in Lipopolysaccharide-Treated Rats. Front Physiol. 2015;6:348 pubmed publisher
Frenay A, Yazdani S, Boersema M, van der Graaf A, Waanders F, van den Born J, et al. Incomplete Restoration of Angiotensin II-Induced Renal Extracellular Matrix Deposition and Inflammation Despite Complete Functional Recovery in Rats. PLoS ONE. 2015;10:e0129732 pubmed publisher
Srodulski S, Sharma S, Bachstetter A, Brelsfoard J, Pascual C, Xie X, et al. Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin. Mol Neurodegener. 2014;9:30 pubmed publisher
Sánchez E, Nieto J, Boullosa A, Vidal S, Sancho F, Rossi G, et al. VSL#3 probiotic treatment decreases bacterial translocation in rats with carbon tetrachloride-induced cirrhosis. Liver Int. 2015;35:735-45 pubmed publisher
Delghingaro Augusto V, Madad L, Chandra A, Simeonovic C, Dahlstrom J, Nolan C. Islet inflammation, hemosiderosis, and fibrosis in intrauterine growth-restricted and high fat-fed Sprague-Dawley rats. Am J Pathol. 2014;184:1446-57 pubmed publisher
Schuh C, Wimmer I, Hametner S, Haider L, van Dam A, Liblau R, et al. Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models. Acta Neuropathol. 2014;128:247-66 pubmed publisher
Fuchs F, Damm J, Gerstberger R, Roth J, Rummel C. Activation of the inflammatory transcription factor nuclear factor interleukin-6 during inflammatory and psychological stress in the brain. J Neuroinflammation. 2013;10:140 pubmed publisher
Solbrig M, Fan Y, Hazelton P. Prospects for cannabinoid therapies in viral encephalitis. Brain Res. 2013;1537:273-82 pubmed publisher
Gu L, Xiong X, Ito T, Lee J, Xu B, KRAMS S, et al. Moderate hypothermia inhibits brain inflammation and attenuates stroke-induced immunodepression in rats. CNS Neurosci Ther. 2014;20:67-75 pubmed publisher
Phan O, Maillard M, Peregaux C, Mordasini D, Stehle J, Funk F, et al. PA21, a new iron-based noncalcium phosphate binder, prevents vascular calcification in chronic renal failure rats. J Pharmacol Exp Ther. 2013;346:281-9 pubmed publisher
Gu L, Xiong X, Wei D, Gao X, KRAMS S, Zhao H. T cells contribute to stroke-induced lymphopenia in rats. PLoS ONE. 2013;8:e59602 pubmed publisher
Tour G, Wendel M, Tcacencu I. Human fibroblast-derived extracellular matrix constructs for bone tissue engineering applications. J Biomed Mater Res A. 2013;101:2826-37 pubmed publisher
Amaral J, Lee J, Chou J, Campos M, Rodriguez I. 7-Ketocholesterol induces inflammation and angiogenesis in vivo: a novel rat model. PLoS ONE. 2013;8:e56099 pubmed publisher
Hoffmann U, Bergler T, Jung B, Steege A, Pace C, Rümmele P, et al. Comprehensive morphometric analysis of mononuclear cell infiltration during experimental renal allograft rejection. Transpl Immunol. 2013;28:24-31 pubmed publisher
Marcus Y, Shefer G, Sasson K, Kohen F, Limor R, Pappo O, et al. Angiotensin 1-7 as means to prevent the metabolic syndrome: lessons from the fructose-fed rat model. Diabetes. 2013;62:1121-30 pubmed publisher
Xiong X, Gu L, Zhang H, Xu B, Zhu S, Zhao H. The protective effects of T cell deficiency against brain injury are ischemic model-dependent in rats. Neurochem Int. 2013;62:265-70 pubmed publisher
Shen Y, Sun A, Wang Y, Cha D, Wang H, Wang F, et al. Upregulation of mesencephalic astrocyte-derived neurotrophic factor in glial cells is associated with ischemia-induced glial activation. J Neuroinflammation. 2012;9:254 pubmed publisher
Denecke C, Yuan X, Ge X, Kim I, Bedi D, Boenisch O, et al. Synergistic effects of prolonged warm ischemia and donor age on the immune response following donation after cardiac death kidney transplantation. Surgery. 2013;153:249-61 pubmed publisher
Hinwood M, Tynan R, Charnley J, Beynon S, Day T, Walker F. Chronic stress induced remodeling of the prefrontal cortex: structural re-organization of microglia and the inhibitory effect of minocycline. Cereb Cortex. 2013;23:1784-97 pubmed publisher
Sosunov A, Wu X, McGovern R, Coughlin D, Mikell C, Goodman R, et al. The mTOR pathway is activated in glial cells in mesial temporal sclerosis. Epilepsia. 2012;53 Suppl 1:78-86 pubmed publisher
Huang J, Ma W, Yokoyama S. Expression and immunolocalization of Gpnmb, a glioma-associated glycoprotein, in normal and inflamed central nervous systems of adult rats. Brain Behav. 2012;2:85-96 pubmed publisher
Huang C, Han X, Li X, Lam E, Peng W, Lou N, et al. Critical role of connexin 43 in secondary expansion of traumatic spinal cord injury. J Neurosci. 2012;32:3333-8 pubmed publisher
Hinwood M, Morandini J, Day T, Walker F. Evidence that microglia mediate the neurobiological effects of chronic psychological stress on the medial prefrontal cortex. Cereb Cortex. 2012;22:1442-54 pubmed publisher
Del Rio R, Moya E, Iturriaga R. Differential expression of pro-inflammatory cytokines, endothelin-1 and nitric oxide synthases in the rat carotid body exposed to intermittent hypoxia. Brain Res. 2011;1395:74-85 pubmed publisher
Kawarazaki H, Ando K, Fujita M, Matsui H, Nagae A, Muraoka K, et al. Mineralocorticoid receptor activation: a major contributor to salt-induced renal injury and hypertension in young rats. Am J Physiol Renal Physiol. 2011;300:F1402-9 pubmed publisher
Li X, Zhang X, Cmarik J, Ruscetti S. Importance of macrophage inflammatory protein-1α and splenic macrophages in neurodegeneration induced by PVC-211 murine leukemia virus. Virology. 2011;409:198-203 pubmed publisher
Kawarazaki H, Ando K, Nagae A, Fujita M, Matsui H, Fujita T. Mineralocorticoid receptor activation contributes to salt-induced hypertension and renal injury in prepubertal Dahl salt-sensitive rats. Nephrol Dial Transplant. 2010;25:2879-89 pubmed publisher
Seki K, Sanada S, Kudinova A, Steinhauser M, Handa V, Gannon J, et al. Interleukin-33 prevents apoptosis and improves survival after experimental myocardial infarction through ST2 signaling. Circ Heart Fail. 2009;2:684-91 pubmed publisher
Ujula T, Salomäki S, Autio A, Luoto P, Tolvanen T, Lehikoinen P, et al. 68Ga-chloride PET reveals human pancreatic adenocarcinoma xenografts in rats--comparison with FDG. Mol Imaging Biol. 2010;12:259-68 pubmed publisher
Li X, Hanson C, Cmarik J, Ruscetti S. Neurodegeneration induced by PVC-211 murine leukemia virus is associated with increased levels of vascular endothelial growth factor and macrophage inflammatory protein 1 alpha and is inhibited by blocking activation of microglia. J Virol. 2009;83:4912-22 pubmed publisher
Zhang W, Chen X, Zhang W, Zhang F, Xiang S, Dong H, et al. Hepatic non-parenchymal cells and extracellular matrix participate in oval cell-mediated liver regeneration. World J Gastroenterol. 2009;15:552-60 pubmed
Mathey E, Derfuss T, Storch M, Williams K, Hales K, Woolley D, et al. Neurofascin as a novel target for autoantibody-mediated axonal injury. J Exp Med. 2007;204:2363-72 pubmed
Ghiringhelli F, Puig P, Roux S, Parcellier A, Schmitt E, Solary E, et al. Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation. J Exp Med. 2005;202:919-29 pubmed
Hendriks J, Alblas J, van der Pol S, van Tol E, Dijkstra C, de Vries H. Flavonoids influence monocytic GTPase activity and are protective in experimental allergic encephalitis. J Exp Med. 2004;200:1667-72 pubmed
Kerschensteiner M, Bareyre F, Buddeberg B, Merkler D, Stadelmann C, Bruck W, et al. Remodeling of axonal connections contributes to recovery in an animal model of multiple sclerosis. J Exp Med. 2004;200:1027-38 pubmed
image
image 1 :
Bio-Rad MCA341GA image 1
Staining of rat liver, with induced hepatocellular damage, with Mouse anti Rat CD68, clone ED1 ( MCA341GA )
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA341GA
Description :
Mouse anti Rat CD68
Specificity :
CD68
TargetSpecies :
Rat
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
WB,P,IP,F,C,IF
ApplicationTypes :
Western Blotting,Immunohistology - Paraffin,Immunoprecipitation,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
Cross Reactivities :
Bovine,Horse
Clone :
ED1
Quantity :
0.1 mg
Quantity Value :
0.1
Quantity Type :
mg
Uniprot Accessions :
Q4FZY1
Published Synonyms :
ED1
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,Biotin,FITC,Purified,RPE,Alexa Fluor® 700
UNSPSC :
41116161
Concentration :
IgG concentration 0.5 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
212
PriceEUR :
298
PriceUSD :
298 USD
PriceCHF :
324
PriceSEK :
3248
PriceNOK :
3264
PriceDKK :
2222
more info or order :
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.