product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Chimeric Human IgE anti NP
catalog :
MCA333S
quantity :
2 ml
price :
702 USD
clonality :
monoclonal
host :
human
conjugate :
nonconjugated
clone name :
JW8/1
application :
ELISA
more info or order :
citations: 2
Reference
Blatner N, Tsai F, Khazaie K. Methods for the study of mast cells in cancer. Methods Mol Biol. 2015;1220:443-60 pubmed publisher
Zhao W, Kepley C, Morel P, Okumoto L, Fukuoka Y, Schwartz L. Fc gamma RIIa, not Fc gamma RIIb, is constitutively and functionally expressed on skin-derived human mast cells. J Immunol. 2006;177:694-701 pubmed
image
image 1 :
Bio-Rad MCA333S image 1
Published customer image: . Chimeric Human IgE anti NP antibody clone JW8/1 ( MCA333S ) used for stimulation of LAD2 cells- in vitro followed by evaluation of -hexosaminidase activity. Image caption: . FcR-dependent functional activity in primary human immune cells is inhibited by CC-509. When stimulated through the indicated FcR, CC-509 inhibits functional activity in (A) primary human macrophage, (B) primary human B-cells and (C) the LAD2 human mast cell line. (D) Left panel: CC-509 inhibits CD63 upregulation on basophils stimulated through indicated FcR in human whole blood. Right panel: Representative flow-cytometry plot showing the number of events and CD63 mean fluorescence intensity (MFI) on unstimulated (brown trace) or stimulated basophils in the presence of 0.1 μM (blue trace), 1.0 uM (green trace), or 10.0 uM (red trace) CC-509. IC50 values (uM) are indicated in upper-right portion of each panel. All data expressed as percent of DMSO-treated control, mean ± SD. From: Ferguson GD, Delgado M, Plantevin-Krenitsky V, Jensen-Pergakes K, Bates RJ, Torres S, et al . (2016). A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation. PLoS ONE 11(1): e0145705 .
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA333S
Description :
Chimeric Human IgE anti NP
Specificity :
Chimeric Human IgE anti NP
TargetSpecies :
Human
Host :
Human
Format :
S/N
Isotypes :
IgE
Applications :
E,FN
ApplicationTypes :
ELISA,Functional Assays
Clone :
JW8/1
Quantity :
2 ml
Quantity Value :
2
Quantity Type :
ml
Entity Formats :
S/N
UNSPSC :
41116161
Product Form :
Tissue Culture Supernatant - liquid
PriceGBP :
502
PriceEUR :
702
PriceUSD :
702 USD
PriceCHF :
764
PriceSEK :
7652
PriceNOK :
7690
PriceDKK :
5234
NotForSaleInCountries :
AU
more info or order :
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.