product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Rat CD11b
catalog :
MCA275R
quantity :
0.25 mg
price :
406 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OX-42
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 71
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; rat; 1:500; loading ...; fig s2c
Nomura Komoike K, Saitoh F, Fujieda H. Phosphatidylserine recognition and Rac1 activation are required for Müller glia proliferation, gliosis and phagocytosis after retinal injury. Sci Rep. 2020;10:1488 pubmed publisher
  • immunocytochemistry; rat; 1:200; loading ...; fig s1l
Neumann B, Baror R, Zhao C, SEGEL M, Dietmann S, Rawji K, et al. Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells. Cell Stem Cell. 2019;25:473-485.e8 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:100; fig 3
Delbary Gossart S, Lee S, Baroni M, Lamarche I, Arnone M, Canolle B, et al. A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury. Brain. 2016;139:1762-82 pubmed publisher
  • immunohistochemistry - frozen section; rat; fig 2
  • western blot; rat; 1:3000; fig 2
Liu Z, Wang S, Liu J, Wang F, Liu Y, Zhao Y. Leukocyte Infiltration Triggers Seizure Recurrence in a Rat Model of Temporal Lobe Epilepsy. Inflammation. 2016;39:1090-8 pubmed publisher
  • flow cytometry; rat; fig s6e
Flach A, Litke T, Strauss J, Haberl M, Gómez C, Reindl M, et al. Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease. Proc Natl Acad Sci U S A. 2016;113:3323-8 pubmed publisher
  • flow cytometry; rat
Schläger C, Körner H, Krueger M, Vidoli S, Haberl M, Mielke D, et al. Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid. Nature. 2016;530:349-53 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:300; fig 5
Backes H, Walberer M, Ladwig A, Rueger M, Neumaier B, Endepols H, et al. Glucose consumption of inflammatory cells masks metabolic deficits in the brain. Neuroimage. 2016;128:54-62 pubmed publisher
  • immunohistochemistry; rat; 1:100
Zheng Y, Smithies H, Aitken P, Gliddon C, Stiles L, Darlington C, et al. Cell proliferation in the cochlear nucleus following acoustic trauma in rat. Neuroscience. 2015;303:524-34 pubmed publisher
  • immunohistochemistry; rat
Chen W, Chen C, Chen N, Sung C, Wen Z. Neuroprotective Effects of Direct Intrathecal Administration of Granulocyte Colony-Stimulating Factor in Rats with Spinal Cord Injury. CNS Neurosci Ther. 2015;21:698-707 pubmed publisher
  • immunocytochemistry; rat; 1:200
Greenlee J, Clawson S, Hill K, Wood B, Clardy S, Tsunoda I, et al. Anti-Yo antibody uptake and interaction with its intracellular target antigen causes Purkinje cell death in rat cerebellar slice cultures: a possible mechanism for paraneoplastic cerebellar degeneration in humans with gynecological or breast cancers. PLoS ONE. 2015;10:e0123446 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:1000; loading ...; fig 3e
Gaudet A, Sweet D, Polinski N, Guan Z, Popovich P. Galectin-1 in injured rat spinal cord: implications for macrophage phagocytosis and neural repair. Mol Cell Neurosci. 2015;64:84-94 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:400; loading ...; fig 1b
Emmrich J, Ejaz S, Neher J, Williamson D, Baron J. Regional distribution of selective neuronal loss and microglial activation across the MCA territory after transient focal ischemia: quantitative versus semiquantitative systematic immunohistochemical assessment. J Cereb Blood Flow Metab. 2015;35:20-7 pubmed publisher
  • immunocytochemistry; rat
Zhang J, Sun X, Zheng S, Liu X, Jin J, Ren Y, et al. Myelin basic protein induces neuron-specific toxicity by directly damaging the neuronal plasma membrane. PLoS ONE. 2014;9:e108646 pubmed publisher
  • flow cytometry; rat
Lehmann J, Härtig W, Seidel A, Füldner C, Hobohm C, Grosche J, et al. Inflammatory cell recruitment after experimental thromboembolic stroke in rats. Neuroscience. 2014;279:139-54 pubmed publisher
  • immunohistochemistry; rat
Codeluppi S, Fernández Zafra T, Sandor K, Kjell J, Liu Q, Abrams M, et al. Interleukin-6 secretion by astrocytes is dynamically regulated by PI3K-mTOR-calcium signaling. PLoS ONE. 2014;9:e92649 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:2000
Haastert Talini K, Geuna S, Dahlin L, Meyer C, Stenberg L, Freier T, et al. Chitosan tubes of varying degrees of acetylation for bridging peripheral nerve defects. Biomaterials. 2013;34:9886-904 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:1000
  • western blot; rat; 1:1000
Weinberg M, Blake B, McCown T. Opposing actions of hippocampus TNF? receptors on limbic seizure susceptibility. Exp Neurol. 2013;247:429-37 pubmed publisher
  • immunohistochemistry; rat
Oliva A, Kang Y, Furones C, Alonso O, Bruno O, Dietrich W, et al. Phosphodiesterase isoform-specific expression induced by traumatic brain injury. J Neurochem. 2012;123:1019-29 pubmed publisher
  • immunohistochemistry - frozen section; rat
  • immunohistochemistry - frozen section; mouse
Horky L, Galimi F, Gage F, Horner P. Fate of endogenous stem/progenitor cells following spinal cord injury. J Comp Neurol. 2006;498:525-38 pubmed
Baror R, Neumann B, SEGEL M, Chalut K, Fancy S, Schafer D, et al. Transforming growth factor-beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors. Glia. 2019;67:1374-1384 pubmed publisher
Stößel M, Metzen J, Wildhagen V, Helmecke O, Rehra L, Freier T, et al. Long-Term In Vivo Evaluation of Chitosan Nerve Guide Properties with respect to Two Different Sterilization Methods. Biomed Res Int. 2018;2018:6982738 pubmed publisher
Yin J, Li H, Feng C, Zuo Z. Inhibition of brain ischemia-caused notch activation in microglia may contribute to isoflurane postconditioning-induced neuroprotection in male rats. CNS Neurol Disord Drug Targets. 2014;13:718-32 pubmed
Walberer M, Jantzen S, Backes H, Rueger M, Keuters M, Neumaier B, et al. In-vivo detection of inflammation and neurodegeneration in the chronic phase after permanent embolic stroke in rats. Brain Res. 2014;1581:80-8 pubmed publisher
Ouk T, Gautier S, Pétrault M, Montaigne D, Marechal X, Masse I, et al. Effects of the PPAR-? agonist fenofibrate on acute and short-term consequences of brain ischemia. J Cereb Blood Flow Metab. 2014;34:542-51 pubmed publisher
Aouad M, Zell V, Juif P, Lacaud A, Goumon Y, Darbon P, et al. Etifoxine analgesia in experimental monoarthritis: a combined action that protects spinal inhibition and limits central inflammatory processes. Pain. 2014;155:403-12 pubmed publisher
Ejaz S, Anwar K, Ashraf M. MRI and neuropathological validations of the involvement of air pollutants in cortical selective neuronal loss. Environ Sci Pollut Res Int. 2014;21:3351-62 pubmed
Botfield H, Gonzalez A, Abdullah O, Skjolding A, Berry M, McAllister J, et al. Decorin prevents the development of juvenile communicating hydrocephalus. Brain. 2013;136:2842-58 pubmed publisher
Pérez Gómez A, Tasker R. Transient domoic acid excitotoxicity increases BDNF expression and activates both MEK- and PKA-dependent neurogenesis in organotypic hippocampal slices. BMC Neurosci. 2013;14:72 pubmed publisher
de Sousa E, Walter L, Higa G, Casado O, Kihara A. Developmental and functional expression of miRNA-stability related genes in the nervous system. PLoS ONE. 2013;8:e56908 pubmed publisher
Tseng F, Tsai M, Yu L, Fu Y, Huang W, Cheng H. Comparative effects of bone marrow mesenchymal stem cells on lipopolysaccharide-induced microglial activation. Oxid Med Cell Longev. 2013;2013:234179 pubmed publisher
Quirié A, Demougeot C, Bertrand N, Mossiat C, Garnier P, Marie C, et al. Effect of stroke on arginase expression and localization in the rat brain. Eur J Neurosci. 2013;37:1193-202 pubmed publisher
Ejaz S, Williamson D, Ahmed T, Sitnikov S, Hong Y, Sawiak S, et al. Characterizing infarction and selective neuronal loss following temporary focal cerebral ischemia in the rat: a multi-modality imaging study. Neurobiol Dis. 2013;51:120-32 pubmed publisher
Tai K, Quintino L, Isaksson C, Gussing F, Lundberg C. Destabilizing domains mediate reversible transgene expression in the brain. PLoS ONE. 2012;7:e46269 pubmed publisher
Okamura T, Katayama T, Obinata C, Iso Y, Chiba Y, Kobayashi H, et al. Neuronal injury induces microglial production of macrophage inflammatory protein-1? in rat corticostriatal slice cultures. J Neurosci Res. 2012;90:2127-33 pubmed publisher
Claus H, Walberer M, Simard M, Emig B, Muesken S, Rueger M, et al. NG2 and NG2-positive cells delineate focal cerebral infarct demarcation in rats. Neuropathology. 2013;33:30-8 pubmed publisher
Rueger M, Muesken S, Walberer M, Jantzen S, Schnakenburg K, Backes H, et al. Effects of minocycline on endogenous neural stem cells after experimental stroke. Neuroscience. 2012;215:174-83 pubmed publisher
Perez Gomez A, Tasker R. Enhanced neurogenesis in organotypic cultures of rat hippocampus after transient subfield-selective excitotoxic insult induced by domoic acid. Neuroscience. 2012;208:97-108 pubmed publisher
Juif P, Anton F, Hanesch U. Pain behavior and spinal cell activation due to carrageenan-induced inflammation in two inbred rat strains with differential hypothalamic-pituitary-adrenal axis reactivity. Physiol Behav. 2012;105:901-8 pubmed publisher
Hughes J, Jones P, Beech J, Wang D, Menon D, Aigbirhio F, et al. A microPET study of the regional distribution of [11C]-PK11195 binding following temporary focal cerebral ischemia in the rat. Correlation with post mortem mapping of microglia activation. Neuroimage. 2012;59:2007-16 pubmed publisher
Whittaker M, Zai L, Lee H, Pajoohesh Ganji A, Wu J, Sharp A, et al. GGF2 (Nrg1-?3) treatment enhances NG2+ cell response and improves functional recovery after spinal cord injury. Glia. 2012;60:281-94 pubmed publisher
Schnichels S, Heiduschka P, Julien S. RGMA and neogenin protein expression are influenced by lens injury following optic nerve crush in the rat retina. Graefes Arch Clin Exp Ophthalmol. 2012;250:39-50 pubmed publisher
Wohl S, Schmeer C, Friese T, Witte O, Isenmann S. In situ dividing and phagocytosing retinal microglia express nestin, vimentin, and NG2 in vivo. PLoS ONE. 2011;6:e22408 pubmed publisher
Subramanian P, Crawford S, Becerra S. Assays for the antiangiogenic and neurotrophic serpin pigment epithelium-derived factor. Methods Enzymol. 2011;499:183-204 pubmed publisher
Horrillo D, Sierra J, Arribas C, García San Frutos M, Carrascosa J, Lauzurica N, et al. Age-associated development of inflammation in Wistar rats: Effects of caloric restriction. Arch Physiol Biochem. 2011;117:140-50 pubmed publisher
Walberer M, Rueger M, Simard M, Emig B, Jander S, Fink G, et al. Dynamics of neuroinflammation in the macrosphere model of arterio-arterial embolic focal ischemia: an approximation to human stroke patterns. Exp Transl Stroke Med. 2010;2:22 pubmed publisher
Chocyk A, Dudys D, Przyborowska A, Majcher I, Mackowiak M, Wedzony K. Maternal separation affects the number, proliferation and apoptosis of glia cells in the substantia nigra and ventral tegmental area of juvenile rats. Neuroscience. 2011;173:1-18 pubmed publisher
Grace P, Hutchinson M, Manavis J, Somogyi A, Rolan P. A novel animal model of graded neuropathic pain: utility to investigate mechanisms of population heterogeneity. J Neurosci Methods. 2010;193:47-53 pubmed publisher
Moro N, Sutton R. Beneficial effects of sodium or ethyl pyruvate after traumatic brain injury in the rat. Exp Neurol. 2010;225:391-401 pubmed publisher
Katayama T, Sakaguchi E, Komatsu Y, Oguma T, Uehara T, Minami M. Sustained activation of ERK signaling in astrocytes is critical for neuronal injury-induced monocyte chemoattractant protein-1 production in rat corticostriatal slice cultures. Eur J Neurosci. 2010;31:1359-67 pubmed publisher
Ambrosi G, Armentero M, Levandis G, Bramanti P, Nappi G, Blandini F. Effects of early and delayed treatment with an mGluR5 antagonist on motor impairment, nigrostriatal damage and neuroinflammation in a rodent model of Parkinson's disease. Brain Res Bull. 2010;82:29-38 pubmed publisher
Ouk T, Laprais M, Bastide M, Mostafa K, Gautier S, Bordet R. Withdrawal of fenofibrate treatment partially abrogates preventive neuroprotection in stroke via loss of vascular protection. Vascul Pharmacol. 2009;51:323-30 pubmed publisher
Hughes J, Beech J, Jones P, Wang D, Menon D, Baron J. Mapping selective neuronal loss and microglial activation in the salvaged neocortical penumbra in the rat. Neuroimage. 2010;49:19-31 pubmed publisher
Carlsson Y, Leverin A, Hedtjarn M, Wang X, Mallard C, Hagberg H. Role of mixed lineage kinase inhibition in neonatal hypoxia-ischemia. Dev Neurosci. 2009;31:420-6 pubmed publisher
Wang Q, van Hoecke M, Tang X, Lee H, Zheng Z, Swanson R, et al. Pyruvate protects against experimental stroke via an anti-inflammatory mechanism. Neurobiol Dis. 2009;36:223-31 pubmed publisher
Lin H, Huang C, Chang K. Lipopolysaccharide preconditioning reduces neuroinflammation against hypoxic ischemia and provides long-term outcome of neuroprotection in neonatal rat. Pediatr Res. 2009;66:254-9 pubmed publisher
Moreira T, Pierre K, Maekawa F, Repond C, Cebere A, Liljequist S, et al. Enhanced cerebral expression of MCT1 and MCT2 in a rat ischemia model occurs in activated microglial cells. J Cereb Blood Flow Metab. 2009;29:1273-83 pubmed publisher
Schroeter M, Dennin M, Walberer M, Backes H, Neumaier B, Fink G, et al. Neuroinflammation extends brain tissue at risk to vital peri-infarct tissue: a double tracer [11C]PK11195- and [18F]FDG-PET study. J Cereb Blood Flow Metab. 2009;29:1216-25 pubmed publisher
Schmid H, Herrmann T, Kohler K, Stett A. Neuroprotective effect of transretinal electrical stimulation on neurons in the inner nuclear layer of the degenerated retina. Brain Res Bull. 2009;79:15-25 pubmed publisher
Yang L, Sun H, Wu L, Guo X, Dou H, Tso M, et al. Baicalein reduces inflammatory process in a rodent model of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2009;50:2319-27 pubmed publisher
Lau P, Verrier J, Nielsen J, Johnson K, Notterpek L, Hudson L. Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytes. J Neurosci. 2008;28:11720-30 pubmed publisher
Kim D, Kim J, Kwak S, Choi K, Kim D, Kwon O, et al. Spatiotemporal characteristics of astroglial death in the rat hippocampo-entorhinal complex following pilocarpine-induced status epilepticus. J Comp Neurol. 2008;511:581-98 pubmed publisher
Norsted E, Gömüç B, Meister B. Protein components of the blood-brain barrier (BBB) in the mediobasal hypothalamus. J Chem Neuroanat. 2008;36:107-21 pubmed publisher
Reimsnider S, Manfredsson F, Muzyczka N, Mandel R. Time course of transgene expression after intrastriatal pseudotyped rAAV2/1, rAAV2/2, rAAV2/5, and rAAV2/8 transduction in the rat. Mol Ther. 2007;15:1504-11 pubmed
Moreira T, Cebere A, Cebers G, Ostenson C, Efendic S, Liljequist S. Reduced HO-1 protein expression is associated with more severe neurodegeneration after transient ischemia induced by cortical compression in diabetic Goto-Kakizaki rats. J Cereb Blood Flow Metab. 2007;27:1710-23 pubmed
Campos M, Amaral J, Becerra S, Fariss R. A novel imaging technique for experimental choroidal neovascularization. Invest Ophthalmol Vis Sci. 2006;47:5163-70 pubmed
Chang M, Wu C, Chien H, Jiang Shieh Y, Shieh J, Wen C. Microglia/macrophages responses to kainate-induced injury in the rat retina. Neurosci Res. 2006;54:202-12 pubmed
Huuskonen J, Suuronen T, Miettinen R, van Groen T, Salminen A. A refined in vitro model to study inflammatory responses in organotypic membrane culture of postnatal rat hippocampal slices. J Neuroinflammation. 2005;2:25 pubmed
Jiang Shieh Y, Yeh K, Wei I, Chang C, Chien H, Tsai R, et al. Responses of microglia in vitro to the gram-positive bacterial component, lipoteichoic acid. J Neurosci Res. 2005;82:515-24 pubmed
Brambilla R, Bracchi Ricard V, Hu W, Frydel B, Bramwell A, Karmally S, et al. Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury. J Exp Med. 2005;202:145-56 pubmed
Jiang Shieh Y, Wu C, Chien H, Wei I, Chang M, Shieh J, et al. Reactive changes of interstitial glia and pinealocytes in the rat pineal gland challenged with cell wall components from gram-positive and -negative bacteria. J Pineal Res. 2005;38:17-26 pubmed
Villa P, Bigini P, Mennini T, Agnello D, Laragione T, Cagnotto A, et al. Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis. J Exp Med. 2003;198:971-5 pubmed
image
image 1 :
Bio-Rad MCA275R image 1
Immunoperoxidase staining of rat lymph node cryosection with Mouse anti Rat CD11b antibody ( MCA275R ) followed by horseradish peroxidase conjugated Goat anti Mouse IgG2a ( STAR133P ) as a detection reagent. Low power
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA275R
Description :
Mouse anti Rat CD11b
Specificity :
CD11b
TargetSpecies :
Rat
Host :
Mouse
Format :
Purified
Isotypes :
IgG2a
Applications :
IP,F,C,IF
ApplicationTypes :
Immunoprecipitation,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
Clone :
OX-42
Quantity :
0.25 mg
Quantity Value :
0.25
Quantity Type :
mg
Published Synonyms :
Integrin Alpha M Chain,MAC-1
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,Biotin,FITC,Pacific Blue®,Purified,RPE,Alexa Fluor® 700
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
290
PriceEUR :
406
PriceUSD :
406 USD
PriceCHF :
442
PriceSEK :
4628
PriceNOK :
4622
PriceDKK :
3028
more info or order :
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.