product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Rat CD11b
catalog :
MCA275G
quantity :
1 mg
price :
680 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OX-42
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
Bio-Rad product webpage
citations: 60
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; rat; 1:250; loading ...; fig s3a
Jones I, Novikova L, Wiberg M, Carlsson L, Novikov L. Human Embryonic Stem Cell-derived Neural Crest Cells Promote Sprouting and Motor Recovery Following Spinal Cord Injury in Adult Rats. Cell Transplant. 2021;30:963689720988245 pubmed publisher
  • immunocytochemistry; rat; 1:1000; loading ...; fig 7a
Mecha M, Yanguas Casás N, Feliú A, Mestre L, Carrillo Salinas F, Riecken K, et al. Involvement of Wnt7a in the role of M2c microglia in neural stem cell oligodendrogenesis. J Neuroinflammation. 2020;17:88 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:1000; loading ...; fig 7c
Liu J, Liu Z, Liu G, Gao K, Zhou H, Zhao Y, et al. Spinal cord injury and its underlying mechanism in rats with temporal lobe epilepsy. Exp Ther Med. 2020;19:2103-2112 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:500; loading ...; fig 1h
Beazley Long N, Moss C, Ashby W, Bestall S, Almahasneh F, Durrant A, et al. VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis. Brain Behav Immun. 2018;74:49-67 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 6c
Cho K, Yoon D, Qiu S, Danziger Z, Grill W, Wetsel W, et al. Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes. Dis Model Mech. 2017;10:559-579 pubmed publisher
  • immunohistochemistry - frozen section; rat; fig 3
Bednarczyk J, Dębski K, Bot A, Lukasiuk K. MBD3 expression and DNA binding patterns are altered in a rat model of temporal lobe epilepsy. Sci Rep. 2016;6:33736 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:100; fig 2
Xu Y, Liu J, He M, Liu R, Belegu V, Dai P, et al. Mechanisms of PDGF siRNA-mediated inhibition of bone cancer pain in the spinal cord. Sci Rep. 2016;6:27512 pubmed publisher
  • immunohistochemistry; rat; 1:1000; fig 4
Heuer A, Kirkeby A, Pfisterer U, Jönsson M, Parmar M. hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation. Exp Neurol. 2016;282:78-85 pubmed publisher
  • flow cytometry; rat; fig s6e
Flach A, Litke T, Strauss J, Haberl M, Gómez C, Reindl M, et al. Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease. Proc Natl Acad Sci U S A. 2016;113:3323-8 pubmed publisher
  • flow cytometry; rat
Schläger C, Körner H, Krueger M, Vidoli S, Haberl M, Mielke D, et al. Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid. Nature. 2016;530:349-53 pubmed publisher
  • immunohistochemistry; rat; 1:1000; loading ...; tbl 1
Ang S, Lee A, Foo F, Ng L, Low C, Khanna S. GABAergic neurons of the medial septum play a nodal role in facilitation of nociception-induced affect. Sci Rep. 2015;5:15419 pubmed publisher
  • immunohistochemistry; rat
Chen W, Chen C, Chen N, Sung C, Wen Z. Neuroprotective Effects of Direct Intrathecal Administration of Granulocyte Colony-Stimulating Factor in Rats with Spinal Cord Injury. CNS Neurosci Ther. 2015;21:698-707 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:1000; loading ...; fig 3e
Gaudet A, Sweet D, Polinski N, Guan Z, Popovich P. Galectin-1 in injured rat spinal cord: implications for macrophage phagocytosis and neural repair. Mol Cell Neurosci. 2015;64:84-94 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:100
Fuentes Santamaría V, Alvarado J, López Muñoz D, Melgar Rojas P, Gabaldón Ull M, Juiz J. Glia-related mechanisms in the anteroventral cochlear nucleus of the adult rat in response to unilateral conductive hearing loss. Front Neurosci. 2014;8:319 pubmed publisher
  • flow cytometry; rat
Lehmann J, Härtig W, Seidel A, Füldner C, Hobohm C, Grosche J, et al. Inflammatory cell recruitment after experimental thromboembolic stroke in rats. Neuroscience. 2014;279:139-54 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:500; fig 5
D cs K, Hegyi Z, Holl K, Kis G, Heged s K, Antal M. Selective axonal and glial distribution of monoacylglycerol lipase immunoreactivity in the superficial spinal dorsal horn of rodents. Brain Struct Funct. 2015;220:2625-37 pubmed publisher
  • immunocytochemistry; human
  • immunocytochemistry; rat
Muirhead G, Dev K. The expression of neuronal sorting nexin 8 (SNX8) exacerbates abnormal cholesterol levels. J Mol Neurosci. 2014;53:125-34 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:1000
  • western blot; rat; 1:1000
Weinberg M, Blake B, McCown T. Opposing actions of hippocampus TNF? receptors on limbic seizure susceptibility. Exp Neurol. 2013;247:429-37 pubmed publisher
Su R, Sun M, Wang W, Zhang J, Zhang L, Zhen J, et al. A Novel Immunosuppressor, (5R)-5-Hydroxytriptolide, Alleviates Movement Disorder and Neuroinflammation in a 6-OHDA Hemiparkinsonian Rat Model. Aging Dis. 2017;8:31-43 pubmed publisher
Breger L, Kienle K, Smith G, Dunnett S, Lane E. Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson's disease. Brain Behav Immun. 2017;61:155-164 pubmed publisher
Wójcik S, Spodnik J, Dziewiątkowski J, Spodnik E, Moryś J. Morphological Changes within the Rat Lateral Ventricle after the Administration of Proteasome Inhibitors. PLoS ONE. 2015;10:e0140536 pubmed publisher
Sanada L, Sato K, Machado N, Carmo E, Sluka K, Fazan V. Cortex glial cells activation, associated with lowered mechanical thresholds and motor dysfunction, persists into adulthood after neonatal pain. Int J Dev Neurosci. 2014;35:55-63 pubmed publisher
Jeong H, Ji K, Kim J, Jou I, Joe E. Repair of astrocytes, blood vessels, and myelin in the injured brain: possible roles of blood monocytes. Mol Brain. 2013;6:28 pubmed publisher
Gauthier M, Kosciuczyk K, Tapley L, Karimi Abdolrezaee S. Dysregulation of the neuregulin-1-ErbB network modulates endogenous oligodendrocyte differentiation and preservation after spinal cord injury. Eur J Neurosci. 2013;38:2693-715 pubmed publisher
Fuentes Santamaria V, Alvarado J, Gabaldón Ull M, Manuel Juiz J. Upregulation of insulin-like growth factor and interleukin 1? occurs in neurons but not in glial cells in the cochlear nucleus following cochlear ablation. J Comp Neurol. 2013;521:3478-99 pubmed publisher
Bali N, Arimoto J, Morgan T, Finch C. Progesterone antagonism of neurite outgrowth depends on microglial activation via Pgrmc1/S2R. Endocrinology. 2013;154:2468-80 pubmed publisher
Wettergren E, Gussing F, Quintino L, Lundberg C. Novel disease-specific promoters for use in gene therapy for Parkinson's disease. Neurosci Lett. 2012;530:29-34 pubmed publisher
Tai K, Quintino L, Isaksson C, Gussing F, Lundberg C. Destabilizing domains mediate reversible transgene expression in the brain. PLoS ONE. 2012;7:e46269 pubmed publisher
Drexel M, Preidt A, Sperk G. Sequel of spontaneous seizures after kainic acid-induced status epilepticus and associated neuropathological changes in the subiculum and entorhinal cortex. Neuropharmacology. 2012;63:806-17 pubmed publisher
Karimi Abdolrezaee S, Schut D, Wang J, Fehlings M. Chondroitinase and growth factors enhance activation and oligodendrocyte differentiation of endogenous neural precursor cells after spinal cord injury. PLoS ONE. 2012;7:e37589 pubmed publisher
Hegyi Z, Holló K, Kis G, Mackie K, Antal M. Differential distribution of diacylglycerol lipase-alpha and N-acylphosphatidylethanolamine-specific phospholipase d immunoreactivity in the superficial spinal dorsal horn of rats. Glia. 2012;60:1316-29 pubmed publisher
Estrada F, Hernandez V, López Hernández E, Corona Morales A, Solís H, Escobar A, et al. Glial activation in a pilocarpine rat model for epileptogenesis: a morphometric and quantitative analysis. Neurosci Lett. 2012;514:51-6 pubmed publisher
Crown E, Gwak Y, Ye Z, Yu Tan H, Johnson K, Xu G, et al. Calcium/calmodulin dependent kinase II contributes to persistent central neuropathic pain following spinal cord injury. Pain. 2012;153:710-21 pubmed publisher
Viscomi M, D Amelio M, Cavallucci V, Latini L, Bisicchia E, Nazio F, et al. Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage. Autophagy. 2012;8:222-35 pubmed publisher
Sheridan G, Dev K. S1P1 receptor subtype inhibits demyelination and regulates chemokine release in cerebellar slice cultures. Glia. 2012;60:382-92 pubmed publisher
Peluffo H, Alí Ruiz D, Ejarque Ortiz A, Heras Alvarez V, Comas Casellas E, Martinez Barriocanal A, et al. Overexpression of the immunoreceptor CD300f has a neuroprotective role in a model of acute brain injury. Brain Pathol. 2012;22:318-28 pubmed publisher
Knerlich Lukoschus F, Noack M, von der Ropp Brenner B, Lucius R, Mehdorn H, Held Feindt J. Spinal cord injuries induce changes in CB1 cannabinoid receptor and C-C chemokine expression in brain areas underlying circuitry of chronic pain conditions. J Neurotrauma. 2011;28:619-34 pubmed publisher
Smith S, Prosser Loose E, Colbourne F, Paterson P. Protein-energy malnutrition alters thermoregulatory homeostasis and the response to brain ischemia. Curr Neurovasc Res. 2011;8:64-74 pubmed
Zhang X, Li L, Chen S, Yang D, Wang Y, Zhang X, et al. Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Autophagy. 2011;7:412-25 pubmed
Knerlich Lukoschus F, von der Ropp Brenner B, Lucius R, Mehdorn H, Held Feindt J. Chemokine expression in the white matter spinal cord precursor niche after force-defined spinal cord contusion injuries in adult rats. Glia. 2010;58:916-31 pubmed publisher
Xue Q, Yang C, Hoffman P, Streit W. Microglial response to murine leukemia virus-induced encephalopathy is a good indicator of neuronal perturbations. Brain Res. 2010;1319:131-41 pubmed publisher
Pettersson J, Lobov S, Novikova L. Labeling of olfactory ensheathing glial cells with fluorescent tracers for neurotransplantation. Brain Res Bull. 2010;81:125-32 pubmed publisher
Rhodes J, Sharkey J, Andrews P. The temporal expression, cellular localization, and inhibition of the chemokines MIP-2 and MCP-1 after traumatic brain injury in the rat. J Neurotrauma. 2009;26:507-25 pubmed publisher
Langdon K, Granter Button S, Corbett D. Persistent behavioral impairments and neuroinflammation following global ischemia in the rat. Eur J Neurosci. 2008;28:2310-8 pubmed publisher
Crown E, Gwak Y, Ye Z, Johnson K, Hulsebosch C. Activation of p38 MAP kinase is involved in central neuropathic pain following spinal cord injury. Exp Neurol. 2008;213:257-67 pubmed publisher
Manning S, Talos D, Zhou C, Selip D, Park H, Park C, et al. NMDA receptor blockade with memantine attenuates white matter injury in a rat model of periventricular leukomalacia. J Neurosci. 2008;28:6670-8 pubmed publisher
Tapia Gonzalez S, Carrero P, Pernia O, Garcia Segura L, Diz Chaves Y. Selective oestrogen receptor (ER) modulators reduce microglia reactivity in vivo after peripheral inflammation: potential role of microglial ERs. J Endocrinol. 2008;198:219-30 pubmed publisher
Immonen R, Kharatishvili I, Sierra A, Einula C, Pitkanen A, Gröhn O. Manganese enhanced MRI detects mossy fiber sprouting rather than neurodegeneration, gliosis or seizure-activity in the epileptic rat hippocampus. Neuroimage. 2008;40:1718-30 pubmed publisher
Casanovas A, Hernandez S, Tarabal O, Rosselló J, Esquerda J. Strong P2X4 purinergic receptor-like immunoreactivity is selectively associated with degenerating neurons in transgenic rodent models of amyotrophic lateral sclerosis. J Comp Neurol. 2008;506:75-92 pubmed
Kim E, Oh C, Kim J, Kim W, Chung Y, Shin D. Reactive astrocytes expressing intense estrogen receptor-alpha immunoreactivities have much elongated cytoplasmic processes: an autopsy case of human cerebellar tissue with multiple genitourinary and gastrointestinal anomalies. J Korean Med Sci. 2007;22:936-41 pubmed
Wong D, Hollister S, Krebsbach P, Nosrat C. Poly(epsilon-caprolactone) and poly (L-lactic-co-glycolic acid) degradable polymer sponges attenuate astrocyte response and lesion growth in acute traumatic brain injury. Tissue Eng. 2007;13:2515-23 pubmed
Gorina R, Sanfeliu C, Galitó A, Messeguer A, Planas A. Exposure of glia to pro-oxidant agents revealed selective Stat1 activation by H2O2 and Jak2-independent antioxidant features of the Jak2 inhibitor AG490. Glia. 2007;55:1313-24 pubmed
Ackman J, Siddiqi F, Walikonis R, LoTurco J. Fusion of microglia with pyramidal neurons after retroviral infection. J Neurosci. 2006;26:11413-22 pubmed
Karwacki Z, Kowiański P, Dziewiatkowski J, Domaradzka Pytel B, Ludkiewicz B, Wojcik S, et al. Quantitative analysis of influence of sevoflurane on the reactivity of microglial cells in the course of the experimental model of intracerebral haemorrhage. Eur J Anaesthesiol. 2006;23:874-81 pubmed
Rojas S, Martin A, Justicia C, Falcon C, Bargallo N, Chamorro A, et al. Modest MRI signal intensity changes precede delayed cortical necrosis after transient focal ischemia in the rat. Stroke. 2006;37:1525-32 pubmed
Karwacki Z, Kowiański P, Dziewiatowski J, Domaradzka Pytel B, Ludkiewicz B, Wójcik S, et al. The effect of propofol on astro- and microglial reactivity in the course of experimental intracerebral haemorrhage in rats. Folia Neuropathol. 2006;44:50-8 pubmed
Mun G, Kim M, Lee J, Kim H, Chung Y, Chung Y, et al. Immunohistochemical study of the distribution of sodium-dependent vitamin C transporters in adult rat brain. J Neurosci Res. 2006;83:919-28 pubmed
Pirttilä T, Lukasiuk K, Hakansson K, Grubb A, Abrahamson M, Pitkanen A. Cystatin C modulates neurodegeneration and neurogenesis following status epilepticus in mouse. Neurobiol Dis. 2005;20:241-53 pubmed
Brambilla R, Bracchi Ricard V, Hu W, Frydel B, Bramwell A, Karmally S, et al. Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury. J Exp Med. 2005;202:145-56 pubmed
Villa P, Bigini P, Mennini T, Agnello D, Laragione T, Cagnotto A, et al. Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis. J Exp Med. 2003;198:971-5 pubmed
image
image 1 :
Bio-Rad MCA275G image 1
Immunoperoxidase staining of rat lymph node cryosection with Mouse anti Rat CD11b antibody ( MCA275R ) followed by horseradish peroxidase conjugated Goat anti Mouse IgG2a ( STAR133P ) as a detection reagent. Low power
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA275G
Description :
Mouse anti Rat CD11b
Specificity :
CD11b
TargetSpecies :
Rat
Host :
Mouse
Format :
Purified
Isotypes :
IgG2a
Applications :
IP,F,C,IF
ApplicationTypes :
Immunoprecipitation,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
Clone :
OX-42
Quantity :
1 mg
Quantity Value :
1
Quantity Type :
mg
Published Synonyms :
Integrin Alpha M Chain,MAC-1
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,Biotin,FITC,Pacific Blue®,Purified,RPE,Alexa Fluor® 700
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
486
PriceEUR :
680
PriceUSD :
680 USD
PriceCHF :
740
PriceSEK :
7752
PriceNOK :
7741
PriceDKK :
5072
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.