product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Hamster anti Mouse CD3
catalog :
MCA2690
quantity :
0.25 mg
price :
372 USD
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
145-2C11
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - free floating section
more info or order :
Bio-Rad product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:500; loading ...; fig s2b
Parang B, Bradley A, Mittal M, Short S, Thompson J, Barrett C, et al. Myeloid translocation genes differentially regulate colorectal cancer programs. Oncogene. 2016;35:6341-6349 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500
Villacampa N, Almolda B, Vilella A, Campbell I, González B, Castellano B. Astrocyte-targeted production of IL-10 induces changes in microglial reactivity and reduces motor neuron death after facial nerve axotomy. Glia. 2015;63:1166-84 pubmed publisher
Muraoka D, Seo N, Hayashi T, Tahara Y, Fujii K, Tawara I, et al. Antigen delivery targeted to tumor-associated macrophages overcomes tumor immune resistance. J Clin Invest. 2019;129:1278-1294 pubmed publisher
Yang F, Dong A, Ahamed J, Sunkara M, Smyth S. Granule cargo release from bone marrow-derived cells sustains cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2014;307:H1529-38 pubmed publisher
Shrivastava K, Chertoff M, Llovera G, Recasens M, Acarin L. Short and long-term analysis and comparison of neurodegeneration and inflammatory cell response in the ipsilateral and contralateral hemisphere of the neonatal mouse brain after hypoxia/ischemia. Neurol Res Int. 2012;2012:781512 pubmed publisher
McDole J, Danzer S, Pun R, Chen Y, Johnson H, Pirko I, et al. Rapid formation of extended processes and engagement of Theiler's virus-infected neurons by CNS-infiltrating CD8 T cells. Am J Pathol. 2010;177:1823-33 pubmed publisher
Kim D, Mebius R, MacMicking J, Jung S, Cupedo T, Castellanos Y, et al. Regulation of peripheral lymph node genesis by the tumor necrosis factor family member TRANCE. J Exp Med. 2000;192:1467-78 pubmed
image
image 1 :
Bio-Rad MCA2690 image 1
Published customer image: . Hamster anti Mouse CD3 antibody, clone 145-2C11 ( MCA2690 ) used for the identification of murine colonic lymphocytes by immunofluorescence. Image caption: . Intestinal Myeloid Cells Respond Directly to Hh Signalling during Homeostasis and Inflammation (A–C) No DSS treatment. (D–F) 4 d of 3% DSS. (A, D) Few CD3+ T lymphocytes respond to Hh signalling during colonic homeostasis. Infiltrating T cells in DSS-induced ulcers do not express Gli1 or respond to Hh signalling. (B, E) Many but not all CD11b+ myeloid cells respond to Hh signalling and express LacZ. After 4 d of DSS, ulcers in Gli1+/lacZ animals are filled with myeloid cells, many of which respond to Hh signals. (C, F) CD11c+ dendritic cells respond directly to Hh signals during homeostasis and inflammation. Nuclear DAPI staining was performed but has been omitted to allow clear visualization of co-expression of nuclear LacZ and cell surface markers. From: Lees CW, Zacharias WJ, Tremelling M, Noble CL, Nimmo ER, Tenesa A, et al . (2008). Analysis of Germline GLI1 Variation Implicates Hedgehog Signalling in the Regulation of Intestinal Inflammatory Pathways. PLoS Med 5(12): e239 .
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA2690
Description :
Hamster anti Mouse CD3
Specificity :
CD3
TargetSpecies :
Mouse
Host :
Hamster
Format :
Purified
Isotypes :
IgG
Applications :
WB,IP,F,C,IF
ApplicationTypes :
Western Blotting,Immunoprecipitation,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
Clone :
145-2C11
Quantity :
0.25 mg
Quantity Value :
0.25
Quantity Type :
mg
GO Accessions :
GO:0001772,GO:0002669,GO:0016021,GO:0004888,GO:0008624,GO:0009897,GO:0032729,GO:0032753,GO:0042105,GO:0045060,GO:0045086,GO:0045879,GO:0046641,GO:0050731,GO:0050850,GO:0050852
GOTerms :
immunological synapse,positive regulation of T cell anergy,integral to membrane,transmembrane receptor activity,induction of apoptosis by extracellular signals,external side of plasma membrane,positive regulation of interferon-gamma production,positive regulation of interleukin-4 production,alpha-beta T cell receptor complex,negative thymic T cell selection,positive regulation of interleukin-2 biosynthetic process,negative regulation of smoothened signaling pathway,positive regulation of alpha-beta T cell proliferation,positive regulation of peptidyl-tyrosine phosphorylation,positive regulation of calcium-mediated signaling,T cell receptor signaling pathway
Uniprot Accessions :
P22646
Gene :
Cd3e
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=12501
Entity Formats :
Purified
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
266
PriceEUR :
372
PriceUSD :
372 USD
PriceCHF :
405
PriceSEK :
4055
PriceNOK :
4075
PriceDKK :
2774
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.