product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Granzyme B
catalog :
MCA2120
quantity :
0.1 mg
price :
249 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GB11
reactivity :
human
application :
ELISA, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
Bio-Rad product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Prinz P, Mendler A, Brech D, Masouris I, Oberneder R, Noessner E. NK-cell dysfunction in human renal carcinoma reveals diacylglycerol kinase as key regulator and target for therapeutic intervention. Int J Cancer. 2014;135:1832-41 pubmed publisher
Wang Q, Che N, Lu C, Sun X, Wang Y, Wang Q, et al. Correlation of peripheral CD4+GranzB+CTLs with disease severity in patients with primary Sjögren's syndrome. Arthritis Res Ther. 2021;23:257 pubmed publisher
image
image 1 :
Bio-Rad MCA2120 image 1
Sandwich ELISA analysis of human granzyme B using Mouse anti Human granzyme B ( MCA2120 ) as a capture reagent and biotinylated Mouse anti Human granzyme B ( MCA2119B ) as a detection reagent with recombinant human granzyme B as antigen. Detection is by HRP conjugated streptavidin and substrate. Microtitre plate is read at O.D. 450 nm on the Bio-Rad iMark Microplate Absorbance Reader ( Bio-Rad Catalog 168-1135 ). Human plasma samples are diluted i:2 (green) and 1:4 (blue)
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA2120
Description :
Mouse anti Granzyme B
Specificity :
Granzyme B
TargetSpecies :
Human
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
F,E,C,IP,IF
ApplicationTypes :
Flow Cytometry,ELISA,Immunohistology - Frozen,Immunoprecipitation,Immunofluorescence
Cross Reactivities :
Chimpanzee,Monkey,Rhesus Monkey
Clone :
GB11
Quantity :
0.1 mg
Quantity Value :
0.1
Quantity Type :
mg
GO Accessions :
GO:0005515,GO:0001772,GO:0004252,GO:0005829,GO:0005634,GO:0006922,GO:0019835,GO:0008629,GO:0008633
GOTerms :
protein binding,immunological synapse,serine-type endopeptidase activity,cytosol,nucleus,cleavage of lamin,cytolysis,induction of apoptosis by intracellular signals,activation of pro-apoptotic gene products
Uniprot Accessions :
P10144
Gene :
GZMB
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3002
Entity Formats :
Purified
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
178
PriceEUR :
249
PriceUSD :
249 USD
PriceCHF :
271
PriceSEK :
2714
PriceNOK :
2728
PriceDKK :
1856
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.