product summary
Loading...
company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Bovine Interleukin-10
catalog :
MCA2110
quantity :
0.5 mg
price :
515 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CC318
reactivity :
bovine, domestic sheep
application :
ELISA, flow cytometry
more info or order :
Bio-Rad product webpage
citations: 15
Published Application/Species/Sample/DilutionReference
  • ELISA; domestic sheep; loading ...; fig 3
Melville J, McDonald C, Bischof R, Polglase G, Lim R, Wallace E, et al. Human amnion epithelial cells modulate the inflammatory response to ventilation in preterm lambs. PLoS ONE. 2017;12:e0173572 pubmed publisher
  • ELISA; bovine; loading ...; fig 3
Cassady Cain R, Blackburn E, Bell C, Elshina E, Hope J, Stevens M. Inhibition of Antigen-Specific and Nonspecific Stimulation of Bovine T and B Cells by Lymphostatin from Attaching and Effacing Escherichia coli. Infect Immun. 2017;85: pubmed publisher
  • ELISA; domestic sheep; 0.5 ug/ml
Jimbo S, Griebel P, Babiuk L, Mutwiri G. IL-10 secreting CD21? B cells are present in jejunal Peyer's patches of sheep during fetal development. Cell Tissue Res. 2014;356:417-25 pubmed publisher
Livingstone M, Wattegedera S, Palarea Albaladejo J, Aitchison K, Corbett C, Sait M, et al. Efficacy of Two Chlamydia abortus Subcellular Vaccines in a Pregnant Ewe Challenge Model for Ovine Enzootic Abortion. Vaccines (Basel). 2021;9: pubmed publisher
Jensen K, Gallagher I, Johnston N, Welsh M, Skuce R, Williams J, et al. Variation in the Early Host-Pathogen Interaction of Bovine Macrophages with Divergent Mycobacterium bovis Strains in the United Kingdom. Infect Immun. 2018;86: pubmed publisher
Redondo E, Gazquez A, Vadillo S, Garcia A, Franco A, Masot A. Induction of interleukin-8 and interleukin-12 in neonatal ovine lung following experimental inoculation of bovine respiratory syncytial virus. J Comp Pathol. 2014;150:434-48 pubmed publisher
Eberle K, Waters T, Jensen E, Venn Watson S, Sacco R. Development and application of specific cytokine assays in tissue samples from a bottlenose dolphin with hyperinsulinemia. Front Endocrinol (Lausanne). 2013;4:134 pubmed publisher
Stabel J, Waters W, Bannantine J, Palmer M. Disparate host immunity to Mycobacterium avium subsp. paratuberculosis antigens in calves inoculated with M. avium subsp. paratuberculosis, M. avium subsp. avium, M. kansasii, and M. bovis. Clin Vaccine Immunol. 2013;20:848-57 pubmed publisher
Mikkelsen H, Aagaard C, Nielsen S, Jungersen G. Correlation of antigen-specific IFN-? responses of fresh blood samples from Mycobacterium avium subsp. paratuberculosis infected heifers with responses of day-old samples co-cultured with IL-12 or anti-IL-10 antibodies. Vet Immunol Immunopathol. 2012;147:69-76 pubmed publisher
Stabel J, Waters W, Bannantine J, Lyashchenko K. Mediation of host immune responses after immunization of neonatal calves with a heat-killed Mycobacterium avium subsp. paratuberculosis vaccine. Clin Vaccine Immunol. 2011;18:2079-89 pubmed publisher
Vordermeier M, Ameni G, Glass E. Cytokine responses of Holstein and Sahiwal zebu derived monocytes after mycobacterial infection. Trop Anim Health Prod. 2012;44:651-5 pubmed publisher
den Hartog G, Savelkoul H, Schoemaker R, Tijhaar E, Westphal A, de Ruiter T, et al. Modulation of human immune responses by bovine interleukin-10. PLoS ONE. 2011;6:e18188 pubmed publisher
Stabel J, Robbe Austerman S. Early immune markers associated with Mycobacterium avium subsp. paratuberculosis infection in a neonatal calf model. Clin Vaccine Immunol. 2011;18:393-405 pubmed publisher
Suraud V, Jacques I, Olivier M, Guilloteau L. Acute infection by conjunctival route with Brucella melitensis induces IgG+ cells and IFN-gamma producing cells in peripheral and mucosal lymph nodes in sheep. Microbes Infect. 2008;10:1370-8 pubmed publisher
Karcher E, Bayles D, Bannantine J, Beitz D, Stabel J. Osteopontin: a novel cytokine involved in the regulation of Mycobacterium avium subspecies paratuberculosis infection in periparturient dairy cattle. J Dairy Sci. 2008;91:3079-91 pubmed publisher
image
image 1 :
Bio-Rad MCA2110 image 1
Published customer image: . Mouse anti Bovine interleukin-10 antibody, clone CC318 ( MCA2110 ) used as a capture reagent for the determination of IL-10 levels in ovine plasma by ELISA. Image caption: . Comparison of plasma concentrations of (A) IL-10 and (B) IL-6 measured over time in arthritic sheep treated and untreated with mesenchymal precursor cells (MPC). Each point represents the mean SEM of 7–8 sheep.**** Indicates a statistically significant difference between groups at that time point, p 0.0001. From: Dooley LM, Abdalmula A, Washington EA, Kaufman C, Tudor EM, Ghosh P, et al . (2015). Effect of Mesenchymal Precursor Cells on the Systemic Inflammatory Response and Endothelial Dysfunction in an Ovine Model of Collagen-Induced Arthritis. PLoS ONE 10(5): e0124144 .
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA2110
Description :
Mouse anti Bovine Interleukin-10
Specificity :
IL-10
TargetSpecies :
Bovine
Host :
Mouse
Format :
Purified
Isotypes :
IgG2b
Applications :
F,E,ES
ApplicationTypes :
Flow Cytometry,ELISA,ELISpot
Cross Reactivities :
Horse,Sheep
Clone :
CC318
Quantity :
0.5 mg
Quantity Value :
0.5
Quantity Type :
mg
GO Accessions :
GO:0002237,GO:0002740,GO:0002904,GO:0005125,GO:0005615,GO:0006954,GO:0006955,GO:0030889,GO:0032715,GO:0032800,GO:0042095,GO:0043193,GO:0045019,GO:0045077,GO:0050715,GO:0051045,GO:0051091,GO:0051384
GOTerms :
response to molecule of bacterial origin,negative regulation of cytokine secretion involved in immune response,positive regulation of B cell apoptosis,cytokine activity,extracellular space,inflammatory response,immune response,negative regulation of B cell proliferation,negative regulation of interleukin-6 production,receptor biosynthetic process,interferon-gamma biosynthetic process,positive regulation of gene-specific transcription,negative regulation of nitric oxide biosynthetic process,negative regulation of interferon-gamma biosynthetic process,positive regulation of cytokine secretion,negative regulation of membrane protein ectodomain proteolysis,positive regulation of transcription factor activity,response to glucocorticoid stimulus
Uniprot Accessions :
P43480
Gene :
IL10
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=281246
Entity Formats :
Purified
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
367
PriceEUR :
515
PriceUSD :
515 USD
PriceCHF :
560
PriceSEK :
5614
PriceNOK :
5641
PriceDKK :
3840
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.