product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Huntingtin
catalog :
MCA2051
quantity :
0.1 mg
price :
406 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HDC8A4
reactivity :
human
application :
western blot, immunoprecipitation
more info or order :
Bio-Rad product webpage
citations: 4
Reference
Liu H, Zhang C, Xu J, Jin J, Cheng L, Miao X, et al. Huntingtin silencing delays onset and slows progression of Huntington's disease: a biomarker study. Brain. 2021;: pubmed publisher
Yao Y, Cui X, Al Ramahi I, Sun X, Li B, Hou J, et al. A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity. elife. 2015;4: pubmed publisher
Lazzeroni G, Benicchi T, Heitz F, Magnoni L, Diamanti D, Rossini L, et al. A phenotypic screening assay for modulators of huntingtin-induced transcriptional dysregulation. J Biomol Screen. 2013;18:984-96 pubmed publisher
Li X, Sapp E, Valencia A, Kegel K, Qin Z, Alexander J, et al. A function of huntingtin in guanine nucleotide exchange on Rab11. Neuroreport. 2008;19:1643-7 pubmed publisher
image
image 1 :
Bio-Rad MCA2051 image 1
Total protein extract of normal human cerebral cortex separated as a strip on a 3-12.5% gradient SDS-PAGE gel and Western blotted. The blot was probed with MCA2051
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA2051
Description :
Mouse anti Huntingtin
Specificity :
Huntingtin
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
WB,C,IP
ApplicationTypes :
Western Blotting,Immunohistology - Frozen,Immunoprecipitation
Cross Reactivities :
Mouse,Rabbit,Human
Clone :
HDC8A4
Quantity :
0.1 mg
Quantity Value :
0.1
Quantity Type :
mg
GO Accessions :
GO:0000132,GO:0002039,GO:0005829,GO:0005783,GO:0005624,GO:0005634,GO:0005770,GO:0005776,GO:0005794,GO:0006890,GO:0007030,GO:0030424,GO:0030425,GO:0030659,GO:0034452,GO:0043234,GO:0045505,GO:0047496
GOTerms :
establishment of mitotic spindle orientation,p53 binding,cytosol,endoplasmic reticulum,membrane fraction,nucleus,late endosome,autophagic vacuole,Golgi apparatus,retrograde vesicle-mediated transport, Golgi to ER,Golgi organization,axon,dendrite,cytoplasmic vesicle membrane,dynactin binding,protein complex,dynein intermediate chain binding,vesicle transport along microtubule
Uniprot Accessions :
P42858
Gene :
HTT
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3064
Entity Formats :
Purified
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
290
PriceEUR :
406
PriceUSD :
406 USD
PriceCHF :
442
PriceSEK :
4628
PriceNOK :
4622
PriceDKK :
3028
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.