product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Mouse CD68
catalog :
MCA1957
quantity :
0.25 mg
price :
372 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
FA-11
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
citations: 265
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig s10d
O Shea T, Ao Y, Wang S, Wollenberg A, Kim J, Ramos Espinoza R, et al. Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype in mice. Nat Commun. 2022;13:5702 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 6c
Kaufmann J, Brangsch J, Kader A, Saatz J, Mangarova D, Zacharias M, et al. ADAMTS4-specific MR probe to assess aortic aneurysms in vivo using synthetic peptide libraries. Nat Commun. 2022;13:2867 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s8b
Chou P, Luo C, Wali N, Lin W, Ng S, Wang C, et al. A chemical probe inhibitor targeting STAT1 restricts cancer stem cell traits and angiogenesis in colorectal cancer. J Biomed Sci. 2022;29:20 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4b, 4g
Niemi J, DeFrancesco Oranburg T, Cox A, Lindborg J, Echevarria F, McCluskey J, et al. The Conditioning Lesion Response in Dorsal Root Ganglion Neurons Is Inhibited in Oncomodulin Knock-Out Mice. Eneuro. 2022;9: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 3
Li Y, Acosta F, Quan Y, Li Z, Gu S, Jiang J. Studying macrophage activation in immune-privileged lens through CSF-1 protein intravitreal injection in mouse model. STAR Protoc. 2022;3:101060 pubmed publisher
  • immunohistochemistry; mouse; 1:800; loading ...; fig 1b
Kiepura A, Stachyra K, Wisniewska A, Kus K, Czepiel K, Suski M, et al. The Anti-Atherosclerotic Action of FFAR4 Agonist TUG-891 in ApoE-Knockout Mice Is Associated with Increased Macrophage Polarization towards M2 Phenotype. Int J Mol Sci. 2021;22: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3b
Zhang P, Ohkawa Y, Yamamoto S, Momota H, Kato A, Kaneko K, et al. St8sia1-deficiency in mice alters tumor environments of gliomas, leading to reduced disease severity. Nagoya J Med Sci. 2021;83:535-549 pubmed publisher
  • immunohistochemistry; mouse; 1:250; loading ...; fig s1j
Solano Fonseca R, Metang P, Egge N, Liu Y, Zuurbier K, Sivaprakasam K, et al. Glycolytic preconditioning in astrocytes mitigates trauma-induced neurodegeneration. elife. 2021;10: pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig 5c
Hu Y, Li C, Wang X, Chen W, Qian Y, Dai X. TREM2, Driving the Microglial Polarization, Has a TLR4 Sensitivity Profile After Subarachnoid Hemorrhage. Front Cell Dev Biol. 2021;9:693342 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 1i
Guo D, Yamamoto M, Hernandez C, Khodadadi H, Baban B, Stranahan A. Beige adipocytes mediate the neuroprotective and anti-inflammatory effects of subcutaneous fat in obese mice. Nat Commun. 2021;12:4623 pubmed publisher
  • immunohistochemistry; mouse; 1:400; loading ...; fig 5a
Babcock M, Mikulka C, Wang B, Chandriani S, Chandra S, Xu Y, et al. Substrate reduction therapy for Krabbe disease and metachromatic leukodystrophy using a novel ceramide galactosyltransferase inhibitor. Sci Rep. 2021;11:14486 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s3a
Lin K, Bieri G, Gontier G, Müller S, Smith L, Snethlage C, et al. MHC class I H2-Kb negatively regulates neural progenitor cell proliferation by inhibiting FGFR signaling. PLoS Biol. 2021;19:e3001311 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 3d
Ryu S, Shchukina I, Youm Y, Qing H, Hilliard B, Dlugos T, et al. Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice. elife. 2021;10: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2g
Liu Y, Li Y, Loh Y, Singer J, Zhu W, Macia L, et al. Fiber Derived Microbial Metabolites Prevent Acute Kidney Injury Through G-Protein Coupled Receptors and HDAC Inhibition. Front Cell Dev Biol. 2021;9:648639 pubmed publisher
  • immunohistochemistry; human; 1:200; loading ...
Huang Y, Happonen K, Burrola P, O Connor C, Hah N, Huang L, et al. Microglia use TAM receptors to detect and engulf amyloid β plaques. Nat Immunol. 2021;22:586-594 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 4f
Colombo A, Sadler R, Llovera G, Singh V, Roth S, Heindl S, et al. Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition. elife. 2021;10: pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 2g
Bassal M, Liu J, Jankowiak W, Saftig P, Bartsch U. Rapid and Progressive Loss of Multiple Retinal Cell Types in Cathepsin D-Deficient Mice-An Animal Model of CLN10 Disease. Cells. 2021;10: pubmed publisher
  • immunohistochemistry; mouse; 1:250; loading ...; fig 2b
Voisin M, Shrestha E, Rollet C, Nikain C, Josefs T, Mahe M, et al. Inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in mice. Commun Biol. 2021;4:420 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:600; loading ...; fig 2c
Zarb Y, Sridhar S, Nassiri S, Utz S, Schaffenrath J, Maheshwari U, et al. Microglia control small vessel calcification via TREM2. Sci Adv. 2021;7: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 5h
Safaiyan S, Besson Girard S, Kaya T, Cantuti Castelvetri L, Liu L, Ji H, et al. White matter aging drives microglial diversity. Neuron. 2021;109:1100-1117.e10 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:10; loading ...; fig s1c
Gajeton J, Krukovets I, Yendamuri R, Verbovetskiy D, Vasanji A, Sul L, et al. miR-467 regulates inflammation and blood insulin and glucose. J Cell Mol Med. 2021;25:2549-2562 pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...; fig s2h
Zheng Q, Li G, Wang S, Zhou Y, Liu K, Gao Y, et al. Trisomy 21-induced dysregulation of microglial homeostasis in Alzheimer's brains is mediated by USP25. Sci Adv. 2021;7: pubmed publisher
  • immunohistochemistry - free floating section; mouse; loading ...; fig 2c
Ma C, Hunt J, Selenica M, Sanneh A, Sandusky Beltran L, Watler M, et al. Arginase 1 Insufficiency Precipitates Amyloid-β Deposition and Hastens Behavioral Impairment in a Mouse Model of Amyloidosis. Front Immunol. 2020;11:582998 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1e
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1f
Lv J, Wang H, Cui H, Liu Z, Zhang R, Lu M, et al. Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis. Front Cell Dev Biol. 2020;8:609090 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 6
Varasteh Z, De Rose F, Mohanta S, Li Y, Zhang X, Miritsch B, et al. Imaging atherosclerotic plaques by targeting Galectin-3 and activated macrophages using (89Zr)-DFO- Galectin3-F(ab')2 mAb. Theranostics. 2021;11:1864-1876 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5c
Sharma A, Choi J, Stefanovic N, Al Sharea A, Simpson D, Mukhamedova N, et al. Specific NLRP3 Inhibition Protects Against Diabetes-Associated Atherosclerosis. Diabetes. 2021;70:772-787 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 2
Biechele G, Franzmeier N, Blume T, Ewers M, Luque J, Eckenweber F, et al. Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases. J Neuroinflammation. 2020;17:374 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig s4b
Nakayama A, Albarrán Juárez J, Liang G, Roquid K, Iring A, Tonack S, et al. Disturbed flow-induced Gs-mediated signaling protects against endothelial inflammation and atherosclerosis. JCI Insight. 2020;5: pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 7c
Mia M, Cibi D, Abdul Ghani S, Song W, Tee N, Ghosh S, et al. YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction. PLoS Biol. 2020;18:e3000941 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:250; loading ...; fig 2b
Griffin P, Sheehan P, Dimitry J, Guo C, Kanan M, Lee J, et al. REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis. elife. 2020;9: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 4b
Grubisic V, McClain J, Fried D, Grants I, Rajasekhar P, Csizmadia E, et al. Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation. Cell Rep. 2020;32:108100 pubmed publisher
  • immunohistochemistry; mouse; 1:900; loading ...; fig 3a
Tang S, Fesharaki Zadeh A, Takahashi H, Nies S, Smith L, Luo A, et al. Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy. Acta Neuropathol Commun. 2020;8:96 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500; loading ...; fig 9d
  • western blot; mouse; 1:1000; loading ...; fig 4c
Sebastian Monasor L, Müller S, Colombo A, Tanrioever G, König J, Roth S, et al. Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models. elife. 2020;9: pubmed publisher
  • immunohistochemistry; mouse; 1:300; loading ...; fig 2s2a
Smith R, Ninchoji T, Gordon E, André H, Dejana E, Vestweber D, et al. Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin. elife. 2020;9: pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4f
Chan K, Nestor J, Huerta T, Certain N, Moody G, Kowal C, et al. Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory. Nat Commun. 2020;11:1403 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 4c
Pereira J, Gerber J, Ghidinelli M, Gerber D, Tortola L, Ommer A, et al. Mice carrying an analogous heterozygous dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy. Hum Mol Genet. 2020;29:1253-1273 pubmed publisher
  • immunohistochemistry; mouse; 1:400; loading ...; fig 1e, 2c
Lu H, Kim S, Steelman A, Tracy K, Zhou B, Michaud D, et al. STAT3 signaling in myeloid cells promotes pathogenic myelin-specific T cell differentiation and autoimmune demyelination. Proc Natl Acad Sci U S A. 2020;117:5430-5441 pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig s3f
Rodriguez Ortiz C, Prieto G, Martini A, Forner S, Trujillo Estrada L, LaFerla F, et al. miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease. Aging Cell. 2020;19:e13118 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig 4d
Yang Y, He Z, Xing Z, Zuo Z, Yuan L, Wu Y, et al. Influenza vaccination in early Alzheimer's disease rescues amyloidosis and ameliorates cognitive deficits in APP/PS1 mice by inhibiting regulatory T cells. J Neuroinflammation. 2020;17:65 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s3
Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur R, et al. ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020;11:198 pubmed publisher
  • immunocytochemistry; mouse; 1:200; loading ...; fig 1
El Gaamouch F, Audrain M, Lin W, Beckmann N, Jiang C, Hariharan S, et al. VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice. Mol Neurodegener. 2020;15:4 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 6i
Robison L, Albert N, Camargo L, Anderson B, Salinero A, Riccio D, et al. High-Fat Diet-Induced Obesity Causes Sex-Specific Deficits in Adult Hippocampal Neurogenesis in Mice. Eneuro. 2020;7: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 2a
Kobayakawa K, Ohkawa Y, Yoshizaki S, Tamaru T, Saito T, Kijima K, et al. Macrophage centripetal migration drives spontaneous healing process after spinal cord injury. Sci Adv. 2019;5:eaav5086 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 1d
Ben J, Jiang B, Wang D, Liu Q, Zhang Y, Qi Y, et al. Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation. Nat Commun. 2019;10:1801 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 3a
Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, et al. Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model. Nat Commun. 2019;10:1365 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5a
  • immunohistochemistry; mouse; loading ...; fig 5b
Chakarov S, Lim H, Tan L, Lim S, See P, Lum J, et al. Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches. Science. 2019;363: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 3e
Zhu C, Li B, Frontzek K, Liu Y, Aguzzi A. SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease. J Exp Med. 2019;216:743-756 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5c
Ma W, Silverman S, Zhao L, Villasmil R, Campos M, Amaral J, et al. Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization. elife. 2019;8: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...
Gerber D, Ghidinelli M, Tinelli E, Somandin C, Gerber J, Pereira J, et al. Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function. elife. 2019;8: pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:100; loading ...; fig 1d
Massaro G, Mattar C, Wong A, Sirka E, Buckley S, Herbert B, et al. Fetal gene therapy for neurodegenerative disease of infants. Nat Med. 2018;24:1317-1323 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1h
Saja M, Cook H, Ruseva M, Szajna M, Pickering M, Woollard K, et al. A triglyceride-rich lipoprotein environment exacerbates renal injury in the accelerated nephrotoxic nephritis model. Clin Exp Immunol. 2018;192:337-347 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 7d
Ziegler Waldkirch S, d Errico P, Sauer J, Erny D, Savanthrapadian S, Loreth D, et al. Seed-induced Aβ deposition is modulated by microglia under environmental enrichment in a mouse model of Alzheimer's disease. EMBO J. 2018;37:167-182 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:100; loading ...; fig 2c
Kojima M, Gimenes Júnior J, Chan T, Eliceiri B, Baird A, Costantini T, et al. Exosomes in postshock mesenteric lymph are key mediators of acute lung injury triggering the macrophage activation via Toll-like receptor 4. FASEB J. 2018;32:97-110 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:600; loading ...; fig s2c
Castellano J, Mosher K, Abbey R, McBride A, James M, Berdnik D, et al. Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. Nature. 2017;544:488-492 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 9a
Gawlik K, Holmberg J, Svensson M, Einerborg M, Oliveira B, Deierborg T, et al. Potent pro-inflammatory and pro-fibrotic molecules, osteopontin and galectin-3, are not major disease modulators of laminin α2 chain-deficient muscular dystrophy. Sci Rep. 2017;7:44059 pubmed publisher
  • immunohistochemistry; human; loading ...; fig s2d
Carmona Fontaine C, Deforet M, Akkari L, Thompson C, Joyce J, Xavier J. Metabolic origins of spatial organization in the tumor microenvironment. Proc Natl Acad Sci U S A. 2017;114:2934-2939 pubmed publisher
  • immunohistochemistry; mouse; 1:250; loading ...; fig s4a
He Y, Wang X, Zhang J, Liu Z, Pan W, Shen Y, et al. Association of Serum HMGB2 Levels With In-Stent Restenosis: HMGB2 Promotes Neointimal Hyperplasia in Mice With Femoral Artery Injury and Proliferation and Migration of VSMCs. Arterioscler Thromb Vasc Biol. 2017;37:717-729 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:200; loading ...; fig 1f
Tufail Y, Cook D, Fourgeaud L, Powers C, Merten K, Clark C, et al. Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia. Neuron. 2017;93:574-586.e8 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s7c
Fuster J, MacLauchlan S, Zuriaga M, Polackal M, Ostriker A, Chakraborty R, et al. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice. Science. 2017;355:842-847 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2p
Zhu J, Cifuentes H, Reynolds J, Lamba D. Immunosuppression via Loss of IL2rγ Enhances Long-Term Functional Integration of hESC-Derived Photoreceptors in the Mouse Retina. Cell Stem Cell. 2017;20:374-384.e5 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 3a
Takahashi H, Klein Z, Bhagat S, Kaufman A, Kostylev M, Ikezu T, et al. Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network. Acta Neuropathol. 2017;133:785-807 pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...; fig 1c
  • immunohistochemistry; mouse; 1:100; loading ...; fig 1d
Chao M, Guo J, Cheng W, Zhu X, She Z, Huang Z, et al. Loss of Caspase-Activated DNase Protects Against Atherosclerosis in Apolipoprotein E-Deficient Mice. J Am Heart Assoc. 2016;5: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s1c
Nakaya M, Watari K, Tajima M, Nakaya T, Matsuda S, Ohara H, et al. Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction. J Clin Invest. 2017;127:383-401 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 5c
Sakata K, Araki K, Nakano H, Nishina T, Komazawa Sakon S, Murai S, et al. Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome. Sci Rep. 2016;6:37200 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 6e
Foerster F, Bamberger D, Schupp J, Weilbächer M, Kaps L, Strobl S, et al. Dextran-based therapeutic nanoparticles for hepatic drug delivery. Nanomedicine (Lond). 2016;11:2663-2677 pubmed
  • immunohistochemistry; mouse; loading ...; fig 5
Liu R, Jin J. Deletion of calponin 2 in macrophages alters cytoskeleton-based functions and attenuates the development of atherosclerosis. J Mol Cell Cardiol. 2016;99:87-99 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 7a
Badea A, Kane L, Anderson R, Qi Y, Foster M, Cofer G, et al. The fornix provides multiple biomarkers to characterize circuit disruption in a mouse model of Alzheimer's disease. Neuroimage. 2016;142:498-511 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500; loading ...; fig 6e
Wolf H, Damme M, Stroobants S, D Hooge R, Beck H, Hermans Borgmeyer I, et al. A mouse model for fucosidosis recapitulates storage pathology and neurological features of the milder form of the human disease. Dis Model Mech. 2016;9:1015-28 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:800; loading ...; fig s6a
Lee S, Le Pichon C, Adolfsson O, Gafner V, Pihlgren M, Lin H, et al. Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement. Cell Rep. 2016;16:1690-1700 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 4
Alves S, Marais T, Biferi M, Furling D, Marinello M, El Hachimi K, et al. Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins. Mol Neurodegener. 2016;11:58 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 1e
Aryal B, Rotllan N, Araldi E, Ramírez C, He S, Chousterman B, et al. ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression. Nat Commun. 2016;7:12313 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2c
Parsa R, Lund H, Georgoudaki A, Zhang X, Ortlieb Guerreiro Cacais A, Grommisch D, et al. BAFF-secreting neutrophils drive plasma cell responses during emergency granulopoiesis. J Exp Med. 2016;213:1537-53 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig s6
Neves J, Zhu J, Sousa Victor P, Konjikusic M, Riley R, Chew S, et al. Immune modulation by MANF promotes tissue repair and regenerative success in the retina. Science. 2016;353:aaf3646 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig s2
Evrard S, Lecce L, Michelis K, Nomura Kitabayashi A, Pandey G, Purushothaman K, et al. Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability. Nat Commun. 2016;7:11853 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig 1
Vasek M, Garber C, Dorsey D, Durrant D, Bollman B, Soung A, et al. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. 2016;534:538-43 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 4
Deveza L, Choi J, Lee J, HUANG N, Cooke J, Yang F. Polymer-DNA Nanoparticle-Induced CXCR4 Overexpression Improves Stem Cell Engraftment and Tissue Regeneration in a Mouse Hindlimb Ischemia Model. Theranostics. 2016;6:1176-89 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 2
Shiraishi M, Shintani Y, Shintani Y, Ishida H, Saba R, Yamaguchi A, et al. Alternatively activated macrophages determine repair of the infarcted adult murine heart. J Clin Invest. 2016;126:2151-66 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2c
Hong S, Beja Glasser V, Nfonoyim B, Frouin A, Li S, Ramakrishnan S, et al. Complement and microglia mediate early synapse loss in Alzheimer mouse models. Science. 2016;352:712-716 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 4
Chattopadhyay A, Navab M, Hough G, Grijalva V, Mukherjee P, Fogelman H, et al. Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD. J Lipid Res. 2016;57:832-47 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 6
Tan S, Krasnow M. Developmental origin of lung macrophage diversity. Development. 2016;143:1318-27 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 4 ug/ml; loading ...; fig 1g
Gabunia K, Ellison S, Kelemen S, Kako F, Cornwell W, Rogers T, et al. IL-19 Halts Progression of Atherosclerotic Plaque, Polarizes, and Increases Cholesterol Uptake and Efflux in Macrophages. Am J Pathol. 2016;186:1361-74 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 3d
Bulla R, Tripodo C, Rami D, Ling G, Agostinis C, Guarnotta C, et al. C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation. Nat Commun. 2016;7:10346 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 2e
Sloboda D, Brooks S. Treatment with selectin blocking antibodies after lengthening contractions of mouse muscle blunts neutrophil accumulation but does not reduce damage. Physiol Rep. 2016;4: pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 8
Bennett B, Davis R, Civelek M, Orozco L, Wu J, Qi H, et al. Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. PLoS Genet. 2015;11:e1005711 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 2j
Roth Flach R, Skoura A, Matevossian A, Danai L, Zheng W, Cortes C, et al. Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis. Nat Commun. 2015;6:8995 pubmed publisher
  • immunocytochemistry; mouse; fig 3d
Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, et al. Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth. Nat Immunol. 2016;17:159-68 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 3
Sikora J, Leddy J, Gulinello M, Walkley S. X-linked Christianson syndrome: heterozygous female Slc9a6 knockout mice develop mosaic neuropathological changes and related behavioral abnormalities. Dis Model Mech. 2016;9:13-23 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2h
Loyer X, Paradis V, Hénique C, Vion A, Colnot N, Guerin C, et al. Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression. Gut. 2016;65:1882-1894 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 4
Harney A, Arwert E, Entenberg D, Wang Y, Guo P, Qian B, et al. Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA. Cancer Discov. 2015;5:932-43 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500
Chugh D, Ali I, Bakochi A, Bahonjic E, Etholm L, Ekdahl C. Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2. PLoS ONE. 2015;10:e0132366 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 2
Zhao L, Zabel M, Wang X, Ma W, Shah P, Fariss R, et al. Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration. EMBO Mol Med. 2015;7:1179-97 pubmed publisher
  • flow cytometry; mouse
Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, et al. DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance. Immunity. 2015;42:1143-58 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Ahlers K, Karaçay B, Fuller L, Bonthius D, Dailey M. Transient activation of microglia following acute alcohol exposure in developing mouse neocortex is primarily driven by BAX-dependent neurodegeneration. Glia. 2015;63:1694-713 pubmed publisher
  • immunohistochemistry - frozen section; mouse
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  • immunohistochemistry - frozen section; mouse; fig 1
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image
image 1 :
Bio-Rad MCA1957 image 1
Flow cytometric staining of mouse peritoneal macrophages cells with Rat anti Mouse CD68 ( MCA1957 ) following permeablisation with Leucoperm ( BUF09 ), visualised with Mouse adsorbed FITC conjugated F(ab )2 Goat anti Rat IgG: ( STAR69 )
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA1957
Description :
Rat anti Mouse CD68
Specificity :
CD68
TargetSpecies :
Mouse
Host :
Rat
Format :
Purified
Isotypes :
IgG2a
Applications :
WB,P,IP,F,C,IF
ApplicationTypes :
Western Blotting,Immunohistology - Paraffin,Immunoprecipitation,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
Clone :
FA-11
Quantity :
0.25 mg
Quantity Value :
0.25
Quantity Type :
mg
GO Accessions :
GO:0005886,GO:0016021,GO:0005765,GO:0010008
GOTerms :
plasma membrane,integral to membrane,lysosomal membrane,endosome membrane
Uniprot Accessions :
P31996
Gene :
Cd68
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=12514
Published Synonyms :
Macrosialin
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,Biotin,FITC,Low Endotoxin,Purified,RPE,Alexa Fluor® 700,Amethyst Orange
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
266
PriceEUR :
372
PriceUSD :
372 USD
PriceCHF :
405
PriceSEK :
4055
PriceNOK :
4075
PriceDKK :
2774
more info or order :
company information
Bio-Rad
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