product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Human CD163
catalog :
MCA1853T
quantity :
25 µg
price :
103 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
EDHu-1
reactivity :
human, rhesus macaque
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Bio-Rad product webpage
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:300; loading ...; fig s2n
Zimmer T, Broekaart D, Luinenburg M, Mijnsbergen C, Anink J, Sim N, et al. Balloon cells promote immune system activation in focal cortical dysplasia type 2b. Neuropathol Appl Neurobiol. 2021;47:826-839 pubmed publisher
  • immunohistochemistry; human; 1:400; loading ...; fig 4k
van den Bosch T, Caliskan K, Kraaij M, Constantinescu A, Manintveld O, Leenen P, et al. CD16+ Monocytes and Skewed Macrophage Polarization toward M2 Type Hallmark Heart Transplant Acute Cellular Rejection. Front Immunol. 2017;8:346 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 2a
Janowski A, Colegio O, Hornick E, McNiff J, Martin M, Badovinac V, et al. NLRC4 suppresses melanoma tumor progression independently of inflammasome activation. J Clin Invest. 2016;126:3917-3928 pubmed publisher
  • immunohistochemistry - paraffin section; rhesus macaque; 1:5000; fig 2
Williams D, Engle E, Shirk E, Queen S, Gama L, Mankowski J, et al. Splenic Damage during SIV Infection: Role of T-Cell Depletion and Macrophage Polarization and Infection. Am J Pathol. 2016;186:2068-2087 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Endo N, Tsuboi N, Furuhashi K, Shi Y, Du Q, Abe T, et al. Urinary soluble CD163 level reflects glomerular inflammation in human lupus nephritis. Nephrol Dial Transplant. 2016;31:2023-2033 pubmed
  • immunohistochemistry; human; fig 3d
Val Bernal J, Mayorga M, Terán Villagrá N. Extracutaneous intravascular histiocytosis of the aortic valve: Report of two cases. Pathol Res Pract. 2016;212:258-63 pubmed publisher
  • immunohistochemistry - paraffin section; human; 0.5 ug/ml; loading ...; fig 5a
Soendergaard C, Kvist P, Seidelin J, Pelzer H, Nielsen O. Systemic and intestinal levels of factor XIII-A: the impact of inflammation on expression in macrophage subtypes. J Gastroenterol. 2016;51:796-807 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 6f
Beckmann J, Schubert J, Morhenn H, Grau V, Schnettler R, Lips K. Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis. Cell Tissue Res. 2015;359:465-477 pubmed publisher
  • flow cytometry; rhesus macaque
  • immunohistochemistry; rhesus macaque
Holder G, McGary C, Johnson E, Zheng R, John V, Sugimoto C, et al. Expression of the mannose receptor CD206 in HIV and SIV encephalitis: a phenotypic switch of brain perivascular macrophages with virus infection. J Neuroimmune Pharmacol. 2014;9:716-26 pubmed publisher
  • immunohistochemistry; human
Preza G, Tanner K, Elliott J, Yang O, Anton P, Ochoa M. Antigen-presenting cell candidates for HIV-1 transmission in human distal colonic mucosa defined by CD207 dendritic cells and CD209 macrophages. AIDS Res Hum Retroviruses. 2014;30:241-9 pubmed publisher
Molina Hernandez V, Ruiz Campillo M, Martínez Moreno F, Buffoni L, Martínez Moreno A, Zafra R, et al. A Partially Protective Vaccine for Fasciola hepatica Induced Degeneration of Adult Flukes Associated to a Severe Granulomatous Reaction in Sheep. Animals (Basel). 2021;11: pubmed publisher
Konjevic Sabolek M, Held K, Beltrán E, Niedl A, Meinl E, Hohlfeld R, et al. Communication of CD8+ T cells with mononuclear phagocytes in multiple sclerosis. Ann Clin Transl Neurol. 2019;6:1151-1164 pubmed publisher
Georgouli M, Herraiz C, Crosas Molist E, Fanshawe B, Maiques O, Perdrix A, et al. Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment. Cell. 2019;176:757-774.e23 pubmed publisher
Pedragosa J, Salas Perdomo A, Gallizioli M, Cugota R, Miro Mur F, Briansó F, et al. CNS-border associated macrophages respond to acute ischemic stroke attracting granulocytes and promoting vascular leakage. Acta Neuropathol Commun. 2018;6:76 pubmed publisher
Wang Q, He Z, Huang M, Liu T, Wang Y, Xu H, et al. Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α. Nat Commun. 2018;9:559 pubmed publisher
Hinchcliff M, Toledo D, Taroni J, Wood T, Franks J, Ball M, et al. Mycophenolate Mofetil Treatment of Systemic Sclerosis Reduces Myeloid Cell Numbers and Attenuates the Inflammatory Gene Signature in Skin. J Invest Dermatol. 2018;138:1301-1310 pubmed publisher
image
image 1 :
Bio-Rad MCA1853T image 1
Figure A. Alexa Fluor700 conjugated mouse anti human CD14 ( MCA596A700 ) and Alexa Fluor488 conjugated mouse IgG1 isotype control ( MCA928A488 ). Figure B. Alexa Fluor700 conjugated mouse anti human CD14 ( MCA596A700 ) and Alexa Fluor488 conjugated mouse anti human CD163 ( MCA1853A488 ). All experiments performed on red cell lysed human blood gated on mononuclear cells in the presence of Human Seroblock ( BUF070A ). Data acquired on the ZE5™ cell analyzer.
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA1853T
Description :
Mouse anti Human CD163
Specificity :
CD163
TargetSpecies :
Human
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
WB,P,F,C,E,IF,IY
ApplicationTypes :
Western Blotting,Immunohistology - Paraffin,Flow Cytometry,Immunohistology - Frozen,ELISA,Immunofluorescence,Immunoassay
Cross Reactivities :
Rhesus Monkey,Sheep,Pig,Guinea Pig,Bovine,Cynomolgus monkey
Clone :
EDHu-1
Quantity :
25 µg
Quantity Value :
25
Quantity Type :
µg
GO Accessions :
GO:0005515,GO:0006953,GO:0005576,GO:0005044,GO:0005887
GOTerms :
protein binding,acute-phase response,extracellular region,scavenger receptor activity,integral to plasma membrane
Uniprot Accessions :
Q86VB7
Gene :
CD163
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9332
Entity Formats :
Alexa Fluor® 488,FITC,Purified,RPE,StarBright Blue 700,StarBright Violet 440,StarBright Violet 515,StarBright Violet 610,StarBright Violet 670,StarBright Violet 570,StarBright Violet 710,StarBright Violet 790,StarBright Violet 475,StarBright UltraViolet 400,StarBright UltraViolet 665,StarBright UltraViolet 795,StarBright Violet 760,StarBright UltraViolet 445,StarBright UltraViolet 510,StarBright UltraViolet 740,StarBright UltraViolet 575,StarBright UltraViolet 605
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
74
PriceEUR :
103
PriceUSD :
103 USD
PriceCHF :
112
PriceSEK :
1174
PriceNOK :
1172
PriceDKK :
768
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.