product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Bovine Interleukin-4:RPE
catalog :
MCA1820PE
quantity :
100 Tests
price :
557 USD
clonality :
monoclonal
host :
mouse
conjugate :
RPE
clone name :
CC303
reactivity :
dogs, bovine
application :
flow cytometry
more info or order :
Bio-Rad product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • flow cytometry; bovine; 1:10; loading ...; tbl 2
Moreira M, Costa Pereira C, Alves M, Marteleto B, Ribeiro V, Peruhype Magalhães V, et al. Vaccination against canine leishmaniosis increases the phagocytic activity, nitric oxide production and expression of cell activation/migration molecules in neutrophils and monocytes. Vet Parasitol. 2016;220:33-45 pubmed publisher
  • flow cytometry; dogs; fig 3
Moreira M, Dorneles E, Soares R, Magalhães C, Costa Pereira C, Lage A, et al. Cross-reactivity of commercially available anti-human monoclonal antibodies with canine cytokines: establishment of a reliable panel to detect the functional profile of peripheral blood lymphocytes by intracytoplasmic staining. Acta Vet Scand. 2015;57:51 pubmed publisher
Archer T, Fellman C, Stokes J, Pinchuk L, Lunsford K, Pruett S, et al. Pharmacodynamic monitoring of canine T-cell cytokine responses to oral cyclosporine. J Vet Intern Med. 2011;25:1391-7 pubmed publisher
Fellman C, Stokes J, Archer T, Pinchuk L, Lunsford K, Mackin A. Cyclosporine A affects the in vitro expression of T cell activation-related molecules and cytokines in dogs. Vet Immunol Immunopathol. 2011;140:175-80 pubmed publisher
Platt R, Sponseller B, Chiang Y, Roth J. Cell-mediated immunity evaluation in foals infected with virulent equine herpesvirus-1 by multi-parameter flow cytometry. Vet Immunol Immunopathol. 2010;135:275-81 pubmed publisher
Reber A, Tanner M, Okinaga T, Woolums A, Williams S, Ensley D, et al. Evaluation of multiple immune parameters after vaccination with modified live or killed bovine viral diarrhea virus vaccines. Comp Immunol Microbiol Infect Dis. 2006;29:61-77 pubmed
image
image 1 :
Bio-Rad MCA1820PE image 1
Published customer image: . Mouse anti Bovine interleukin-4 antibody, clone CC303 used for the identification of interferon expressing dog lymphocytes by flow cytometry. Image caption: . Representative dot plots illustrating the analysis of intracellular cytokine profile in T-cell subsets. (A) Pseudocolor plot distribution of short-term in vitro cultured (control or SLA-Ag stimulated) canine whole blood sample according to cell size (Forward scatter - FSC) and granularity (Side scatter- SSC) used for lymphocyte gate selection (R1) of FSCLowSSCLow events. (B) Pseudocolor plots representing cytokines + (IL-17, TNF-α, IFN-γ, TGF-β and IL-4) CD4+ cells within gated lymphocytes and (C) Pseudocolor plots representing cytokines + (IL-17, TNF-α, IFN-γ, TGF-β and IL-4) CD8+ cells within gated lymphocytes. The frequency of cytokines+ T-cells subsets were calculated by quadrant statistics approach and first reported as percentage of gated lymphocytes prior to the calculation of the SLAg/Control indexes. From: Costa-Pereira C, Moreira ML, Soares RP, Marteleto BH, Ribeiro VM, França-Dias MH, Cardoso LM, Viana KF, Giunchetti RC, Martins-Filho OA, Araújo MS. One-year timeline kinetics of cytokine-mediated cellular immunity in dogs vaccinated against visceral leishmaniasis. BMC Vet Res. 2015 Apr 11;11(1):92 .
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA1820PE
Description :
Mouse anti Bovine Interleukin-4:RPE
Specificity :
IL-4
TargetSpecies :
Bovine
Host :
Mouse
Format :
RPE
Conjugate/Tag :
RPE
Isotypes :
IgG2a
Applications :
F
ApplicationTypes :
Flow Cytometry
Cross Reactivities :
Dog,Pig,Sheep,Mustelid,Goat,Dolphin,Mink,Fin Whale
Clone :
CC303
Quantity :
100 Tests
Quantity Value :
100
Quantity Type :
Tests
GO Accessions :
GO:0005125,GO:0005136,GO:0005615,GO:0006955,GO:0008083,GO:0030890,GO:0042113,GO:0043066,GO:0045348,GO:0045671,GO:0045944,GO:0048295,GO:0048304
GOTerms :
cytokine activity,interleukin-4 receptor binding,extracellular space,immune response,growth factor activity,positive regulation of B cell proliferation,B cell activation,negative regulation of apoptosis,positive regulation of MHC class II biosynthetic process,negative regulation of osteoclast differentiation,positive regulation of transcription from RNA polymerase II promoter,positive regulation of isotype switching to IgE isotypes,positive regulation of isotype switching to IgG isotypes
Uniprot Accessions :
P30367
Gene :
IL4
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=280824
Entity Formats :
Alexa Fluor® 647,FITC,Purified,RPE
UNSPSC :
41116161
Product Form :
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
PriceGBP :
397
PriceEUR :
557
PriceUSD :
557 USD
PriceCHF :
606
PriceSEK :
6350
PriceNOK :
6340
PriceDKK :
4154
NotForSaleInCountries :
KR
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.