Mouse anti Bovine Interleukin-4 | Bio-Rad MCA1820 product information

product summary

company name :

Bio-Rad

other brands :

Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology

product type :

antibody

product name :

Mouse anti Bovine Interleukin-4

catalog :

MCA1820

quantity :

0.5 mg

price :

531 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CC303

reactivity :

bovine

application :

western blot, ELISA, flow cytometry

more info or order :

Bio-Rad product webpage

citations: 7

Reference
Lombardi P, Palatucci A, Giovazzino A, Mastellone V, Ruggiero G, Rubino V, et al. Clinical and Immunological Response in Dogs Naturally Infected by L. infantum Treated with a Nutritional Supplement. Animals (Basel). 2019;9: pubmed publisher
Buchanan R, Mertins S, Wilson H. Oral antigen exposure in extreme early life in lambs influences the magnitude of the immune response which can be generated in later life. BMC Vet Res. 2013;9:160 pubmed publisher
Zafra R, Pérez Ecija R, Buffoni L, Pacheco I, Martinez Moreno A, Lacourse E, et al. Early hepatic and peritoneal changes and immune response in goats vaccinated with a recombinant glutathione transferase sigma class and challenged with Fasciola hepatica. Res Vet Sci. 2013;94:602-9 pubmed publisher
Zafra R, Pérez Ecija R, Buffoni L, Mendes R, Martinez Moreno A, Martinez Moreno F, et al. Evaluation of hepatic damage and local immune response in goats immunized with native glutathione S-transferase of Fasciola hepatica. J Comp Pathol. 2010;143:110-9 pubmed publisher
Mendes R, Pérez Ecija R, Zafra R, Buffoni L, Martínez Moreno A, Dalton J, et al. Evaluation of hepatic changes and local and systemic immune responses in goats immunized with recombinant Peroxiredoxin (Prx) and challenged with Fasciola hepatica. Vaccine. 2010;28:2832-40 pubmed publisher
Zafra R, Buffoni L, Pérez Ecija R, Mendes R, Martinez Moreno A, Martinez Moreno F, et al. Study of the local immune response to Fasciola hepatica in the liver and hepatic lymph nodes of goats immunised with a peptide of the Sm14 antigen. Res Vet Sci. 2009;87:226-32 pubmed publisher
Kalina W, Anderson M, Gershwin L. Alternaria aerosol during a bovine respiratory syncytial virus infection alters the severity of subsequent re-infection and enhances IgE production. Comp Immunol Microbiol Infect Dis. 2006;29:138-56 pubmed

image

image 1 :

Published customer image: . Mouse anti Bovine interleukin-4 antibody, clone CC303 used for the identification of interferon expressing dog lymphocytes by flow cytometry. Image caption: . Representative dot plots illustrating the analysis of intracellular cytokine profile in T-cell subsets. (A) Pseudocolor plot distribution of short-term in vitro cultured (control or SLA-Ag stimulated) canine whole blood sample according to cell size (Forward scatter - FSC) and granularity (Side scatter- SSC) used for lymphocyte gate selection (R1) of FSCLowSSCLow events. (B) Pseudocolor plots representing cytokines + (IL-17, TNF-α, IFN-γ, TGF-β and IL-4) CD4+ cells within gated lymphocytes and (C) Pseudocolor plots representing cytokines + (IL-17, TNF-α, IFN-γ, TGF-β and IL-4) CD8+ cells within gated lymphocytes. The frequency of cytokines+ T-cells subsets were calculated by quadrant statistics approach and first reported as percentage of gated lymphocytes prior to the calculation of the SLAg/Control indexes. From: Costa-Pereira C, Moreira ML, Soares RP, Marteleto BH, Ribeiro VM, França-Dias MH, Cardoso LM, Viana KF, Giunchetti RC, Martins-Filho OA, Araújo MS. One-year timeline kinetics of cytokine-mediated cellular immunity in dogs vaccinated against visceral leishmaniasis. BMC Vet Res. 2015 Apr 11;11(1):92 .

product information

Entity Type :

Monoclonal Antibody

Entity Category :

Antibodies

ProductCode :

MCA1820

Description :

Mouse anti Bovine Interleukin-4

Specificity :

IL-4

TargetSpecies :

Bovine

Host :

Mouse

Format :

Purified

Isotypes :

IgG2a

Applications :

F,WB,E

ApplicationTypes :

Flow Cytometry,Western Blotting,ELISA

Cross Reactivities :

Dog,Pig,Sheep,Mustelid,Goat,Dolphin,Mink,Fin Whale

Clone :

CC303

Quantity :

0.5 mg

Quantity Value :

0.5

Quantity Type :

GO Accessions :

GO:0005125,GO:0005136,GO:0005615,GO:0006955,GO:0008083,GO:0030890,GO:0042113,GO:0043066,GO:0045348,GO:0045671,GO:0045944,GO:0048295,GO:0048304

GOTerms :

cytokine activity,interleukin-4 receptor binding,extracellular space,immune response,growth factor activity,positive regulation of B cell proliferation,B cell activation,negative regulation of apoptosis,positive regulation of MHC class II biosynthetic process,negative regulation of osteoclast differentiation,positive regulation of transcription from RNA polymerase II promoter,positive regulation of isotype switching to IgE isotypes,positive regulation of isotype switching to IgG isotypes

Uniprot Accessions :

P30367

Gene :

IL4

GeneID URL :

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=280824

Entity Formats :

Alexa Fluor® 647,FITC,Purified,RPE

UNSPSC :

41116161

Concentration :

IgG concentration 1.0mg/ml

Product Form :

Purified IgG - liquid

PriceGBP :

379

PriceEUR :

531

PriceUSD :

531 USD

PriceCHF :

578

PriceSEK :

6053

PriceNOK :

6044

PriceDKK :

3961

more info or order :

Bio-Rad product webpage

company information

Bio-Rad

Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE

antibody_sales_uk@bio-rad.com

https://www.bio-rad-antibodies.com

1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)

headquarters: UK

Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
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