product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Bovine Interleukin-12/23:Low Endotoxin
catalog :
MCA1782EL
quantity :
0.5 mg
price :
653 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CC301
reactivity :
bovine, domestic sheep
application :
western blot, ELISA, flow cytometry
more info or order :
Bio-Rad product webpage
citations: 5
Published Application/Species/Sample/DilutionReference
  • ELISA; domestic sheep; 8 ug/ml
Jimbo S, Griebel P, Babiuk L, Mutwiri G. IL-10 secreting CD21? B cells are present in jejunal Peyer's patches of sheep during fetal development. Cell Tissue Res. 2014;356:417-25 pubmed publisher
Corripio Miyar Y, Mellanby R, Morrison K, McNeilly T. 1,25-Dihydroxyvitamin D3 modulates the phenotype and function of Monocyte derived dendritic cells in cattle. BMC Vet Res. 2017;13:390 pubmed publisher
Stabel J, Waters W, Bannantine J, Palmer M. Disparate host immunity to Mycobacterium avium subsp. paratuberculosis antigens in calves inoculated with M. avium subsp. paratuberculosis, M. avium subsp. avium, M. kansasii, and M. bovis. Clin Vaccine Immunol. 2013;20:848-57 pubmed publisher
Stabel J, Waters W, Bannantine J, Lyashchenko K. Mediation of host immune responses after immunization of neonatal calves with a heat-killed Mycobacterium avium subsp. paratuberculosis vaccine. Clin Vaccine Immunol. 2011;18:2079-89 pubmed publisher
Vordermeier M, Ameni G, Glass E. Cytokine responses of Holstein and Sahiwal zebu derived monocytes after mycobacterial infection. Trop Anim Health Prod. 2012;44:651-5 pubmed publisher
image
image 1 :
Bio-Rad MCA1782EL image 1
Published customer image: Mouse anti Bovine interleukin 12/23 antibody, clone CC301 ( MCA1782EL ) used as a capture reagent in conjunction with biotinylated Mouse anti Bovine interleukin 12 antibody, clone CC326 ( MCA2173B ) as a detection reagent in a sandwich ELISA for the evaluation of IL-12 production by ovine cells in vitro . Image caption: . IL-12 response (u/ml) in mesenteric lymph nodes against GRA7, TLA, MIC3 and EC2 in function of time. From: Verhelst D, De Craeye S, Entrican G, Dorny P, Cox E. Parasite distribution and associated immune response during the acute phase of Toxoplasma gondii infection in sheep. BMC Vet Res. 2014 Dec 16;10(1):293 .
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA1782EL
Description :
Mouse anti Bovine Interleukin-12/23:Low Endotoxin
Specificity :
IL-12 / IL-23
TargetSpecies :
Bovine
Host :
Mouse
Format :
Low Endotoxin
Isotypes :
IgG2a
Applications :
WB,F,E,FN,ES
ApplicationTypes :
Western Blotting,Flow Cytometry,ELISA,Functional Assays,ELISpot
Cross Reactivities :
Human,Sheep,Mouse,African Buffalo
Clone :
CC301
Quantity :
0.5 mg
Quantity Value :
0.5
Quantity Type :
mg
GO Accessions :
GO:0016020,GO:0004896,GO:0005125,GO:0005143,GO:0030101,GO:0042093,GO:0042095,GO:0042104,GO:0008083
GOTerms :
membrane,cytokine receptor activity,cytokine activity,interleukin-12 receptor binding,natural killer cell activation,T-helper cell differentiation,interferon-gamma biosynthetic process,positive regulation of activated T cell proliferation,growth factor activity
Uniprot Accessions :
P54349,P46282
Gene :
IL12B,IL12A
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=281857, http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=281856
Entity Formats :
Low Endotoxin
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
467
PriceEUR :
653
PriceUSD :
653 USD
PriceCHF :
710
PriceSEK :
7118
PriceNOK :
7153
PriceDKK :
4869
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.