product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Human BRCA1 (N-Terminal)
catalog :
MCA1683GT
quantity :
50 µg
price :
395 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MS13
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
image
image 1 :
Bio-Rad MCA1683GT image 1
Published customer image: . Muse antiHuman BRCA1 antibody, clone MS13 ( MCA1683GT ) used for the demonstration of BRCA1 expressing tumor cells by immunohistochemistry on formalin fixed, paraffin embedded tissue sections. Image caption: . (A) Cytoplasm staining of BRCA1 in neoplastic cells from an oral squamous cell carcinoma (OSCC). (B) Nuclear staining of RAD51 in neoplastic cells from an OSCC. (C) Nuclear staining of p53 in OSCC cells. (D) Nuclear staining of γH2AX in OSCC cells (original magnification ×200 in all photomicrographs). From: Oliveira-Costa JP, Oliveira LR, Zanetti R, Zanetti JS, da Silveira GG, Chavichiolli Buim ME, Zucoloto S, Ribeiro-Silva A, Soares FA. BRCA1 and H2AX as independent prognostic markers in oral squamous cell carcinoma. Oncoscience. 2014 Jun 1;1(5):383-91.
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
Region :
(N-TERMINAL)
ProductCode :
MCA1683GT
Description :
Mouse anti Human BRCA1 (N-Terminal)
Specificity :
BRCA1
TargetSpecies :
Human
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
WB,P,IF,IP
ApplicationTypes :
Western Blotting,Immunohistology - Paraffin,Immunofluorescence,Immunoprecipitation
Clone :
MS13
Quantity :
50 µg
Quantity Value :
50
Quantity Type :
µg
GO Accessions :
GO:0007059,GO:0005515,GO:0000724,GO:0003677,GO:0003713,GO:0003723,GO:0030529,GO:0006915,GO:0004842,GO:0005654,GO:0006301,GO:0006359,GO:0006633,GO:0006978,GO:0007049,GO:0008270,GO:0008274,GO:0008630,GO:0042802,GO:0010212,GO:0010552,GO:0015631,GO:0016481,GO:0016563,GO:0030521,GO:0031398,GO:0031436,GO:0031572,GO:0031625,GO:0042127,GO:0043627,GO:0045717,GO:0045739,GO:0046600,GO:0050681,GO:0051865,GO:0070531,GO:0071681,GO:0085020
GOTerms :
chromosome segregation,protein binding,double-strand break repair via homologous recombination,DNA binding,transcription coactivator activity,RNA binding,ribonucleoprotein complex,apoptosis,ubiquitin-protein ligase activity,nucleoplasm,postreplication repair,regulation of transcription from RNA polymerase III promoter,fatty acid biosynthetic process,DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator,cell cycle,zinc ion binding,gamma-tubulin ring complex,DNA damage response, signal transduction resulting in induction of apoptosis,identical protein binding,response to ionizing radiation,positive regulation of gene-specific transcription from RNA polymerase II promoter,tubulin binding,negative regulation of transcription,transcription activator activity,androgen receptor signaling pathway,positive regulation of protein ubiquitination,BRCA1-BARD1 complex,G2/M transition DNA damage checkpoint,ubiquitin protein ligase binding,regulation of cell proliferation,response to estrogen stimulus,negative regulation of fatty acid biosynthetic process,positive regulation of DNA repair,negative regulation of centriole replication,androgen receptor binding,protein autoubiquitination,BRCA1-A complex,cellular response to indole-3-methanol,protein K6-linked ubiquitination
Uniprot Accessions :
P38398
Gene :
BRCA1
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=672
Published Synonyms :
Breast Cancer Type 1 Susceptibility Protein
Entity Formats :
Purified
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
252
PriceEUR :
292
PriceUSD :
395 USD
PriceCHF :
318
PriceSEK :
3183
PriceNOK :
3199
PriceDKK :
2177
more info or order :
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.