product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Sheep Interleukin-6
catalog :
MCA1659
quantity :
0.25 mg
price :
411 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4B6
reactivity :
domestic sheep
application :
western blot, ELISA, flow cytometry
more info or order :
Bio-Rad product webpage
citations: 10
Published Application/Species/Sample/DilutionReference
  • ELISA; domestic sheep; fig 2
Liu H, Garzoni L, Herry C, Durosier L, Cao M, Burns P, et al. Can Monitoring Fetal Intestinal Inflammation Using Heart Rate Variability Analysis Signal Incipient Necrotizing Enterocolitis of the Neonate?. Pediatr Crit Care Med. 2016;17:e165-76 pubmed publisher
  • ELISA; domestic sheep; 1 ug/ml; fig 4
He X, Su F, Taccone F, Laporte R, Kjølbye A, Zhang J, et al. A Selective V(1A) Receptor Agonist, Selepressin, Is Superior to Arginine Vasopressin and to Norepinephrine in Ovine Septic Shock. Crit Care Med. 2016;44:23-31 pubmed publisher
  • ELISA; domestic sheep; 4 ug/ml; fig 1
Cao M, Cortes M, Moore C, Leong S, Durosier L, Burns P, et al. Fetal microglial phenotype in vitro carries memory of prior in vivo exposure to inflammation. Front Cell Neurosci. 2015;9:294 pubmed publisher
Karisnan K, Bakker A, Song Y, Noble P, Pillow J, Pinniger G. Interleukin-1 receptor antagonist protects against lipopolysaccharide induced diaphragm weakness in preterm lambs. PLoS ONE. 2015;10:e0124390 pubmed publisher
Redondo E, Gazquez A, Vadillo S, Garcia A, Franco A, Masot A. Induction of interleukin-8 and interleukin-12 in neonatal ovine lung following experimental inoculation of bovine respiratory syncytial virus. J Comp Pathol. 2014;150:434-48 pubmed publisher
Payne M, Kemp M, Kallapur S, Kannan P, Saito M, Miura Y, et al. Intrauterine Candida albicans infection elicits severe inflammation in fetal sheep. Pediatr Res. 2014;75:716-22 pubmed publisher
Wester Rosenlöf L, Casslén V, Axelsson J, Edström Hägerwall A, Gram M, Holmqvist M, et al. A1M/?1-microglobulin protects from heme-induced placental and renal damage in a pregnant sheep model of preeclampsia. PLoS ONE. 2014;9:e86353 pubmed publisher
Saito M, Payne M, Miura Y, Ireland D, Stock S, Kallapur S, et al. Polymyxin B agonist capture therapy for intrauterine inflammation: proof-of-principle in a fetal ovine model. Reprod Sci. 2014;21:623-31 pubmed publisher
Su F, Huang H, He X, Simion D, Simuen D, Xie J, et al. Effects of a novel anticoagulant compound (TV7130) in an ovine model of septic shock. Shock. 2010;34:622-7 pubmed publisher
Su F, Wang Z, Cai Y, Rogiers P, Vincent J. Fluid resuscitation in severe sepsis and septic shock: albumin, hydroxyethyl starch, gelatin or ringer's lactate-does it really make a difference?. Shock. 2007;27:520-6 pubmed
image
image 1 :
Bio-Rad MCA1659 image 1
Published customer image: . Mouse anti Ovine Interleukin-6 antibody, clone 4B6 ( MCA1659 ) used as a capture antibody in a sandwich ELISA for the evaluation of IL-6 expression in response to LPS treatment using Rabbit anti Ovine IL-6 antibody ( AHP424 ) as a detection reagent. Image caption: . Fetal inflammatory response to lipopolysaccharide. Blue, control group (n = 5); red, LPS group (n = 10); Mean ± SD. *, P = 0.001 versus control. From: Herry CL, Cortes M, Wu H-T, Durosier LD, Cao M, Burns P, et al. (2016). Temporal Patterns in Sheep Fetal Heart Rate Variability Correlate to Systemic Cytokine Inflammatory Response: A Methodological Exploration of Monitoring Potential Using Complex Signals Bioinformatics. PLoS ONE 11(4): e0153515 .
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA1659
Description :
Mouse anti Sheep Interleukin-6
Specificity :
IL-6
TargetSpecies :
Sheep
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
WB,F,E
ApplicationTypes :
Western Blotting,Flow Cytometry,ELISA
Cross Reactivities :
Monkey
Clone :
4B6
Quantity :
0.25 mg
Quantity Value :
0.25
Quantity Type :
mg
GO Accessions :
GO:0006953,GO:0005125,GO:0005138,GO:0005615,GO:0006955,GO:0008083
GOTerms :
acute-phase response,cytokine activity,interleukin-6 receptor binding,extracellular space,immune response,growth factor activity
Uniprot Accessions :
P29455
Gene :
IL6
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=443406
Entity Formats :
Purified
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
294
PriceEUR :
411
PriceUSD :
411 USD
PriceCHF :
447
PriceSEK :
4480
PriceNOK :
4502
PriceDKK :
3064
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.