product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Mouse anti Sheep Interleukin-1 beta
catalog :
MCA1658
quantity :
0.25 mg
price :
411 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1D4
reactivity :
domestic sheep
application :
western blot, ELISA, flow cytometry
more info or order :
Bio-Rad product webpage
citations: 9
Published Application/Species/Sample/DilutionReference
  • ELISA; domestic sheep; 4 ug/ml; fig 2
Cao M, Cortes M, Moore C, Leong S, Durosier L, Burns P, et al. Fetal microglial phenotype in vitro carries memory of prior in vivo exposure to inflammation. Front Cell Neurosci. 2015;9:294 pubmed publisher
Cortes M, Cao M, Liu H, Burns P, Moore C, Fecteau G, et al. RNAseq profiling of primary microglia and astrocyte cultures in near-term ovine fetus: A glial in vivo-in vitro multi-hit paradigm in large mammalian brain. J Neurosci Methods. 2017;276:23-32 pubmed publisher
Karisnan K, Bakker A, Song Y, Noble P, Pillow J, Pinniger G. Interleukin-1 receptor antagonist protects against lipopolysaccharide induced diaphragm weakness in preterm lambs. PLoS ONE. 2015;10:e0124390 pubmed publisher
Redondo E, Gazquez A, Vadillo S, Garcia A, Franco A, Masot A. Induction of interleukin-8 and interleukin-12 in neonatal ovine lung following experimental inoculation of bovine respiratory syncytial virus. J Comp Pathol. 2014;150:434-48 pubmed publisher
Zhang L, Saito M, Jobe A, Kallapur S, Newnham J, Cox T, et al. Intra-amniotic administration of E coli lipopolysaccharides causes sustained inflammation of the fetal skin in sheep. Reprod Sci. 2012;19:1181-9 pubmed publisher
Kemp M, Saito M, Kallapur S, Jobe A, Keelan J, Li S, et al. Inflammation of the fetal ovine skin following in utero exposure to Ureaplasma parvum. Reprod Sci. 2011;18:1128-37 pubmed publisher
Vordermeier M, Ameni G, Glass E. Cytokine responses of Holstein and Sahiwal zebu derived monocytes after mycobacterial infection. Trop Anim Health Prod. 2012;44:651-5 pubmed publisher
Simojoki H, Salomäki T, Taponen S, Iivanainen A, Pyörälä S. Innate immune response in experimentally induced bovine intramammary infection with Staphylococcus simulans and S. epidermidis. Vet Res. 2011;42:49 pubmed publisher
Dernfalk J, Persson Waller K, Johannisson A. The xMAP technique can be used for detection of the inflammatory cytokines IL-1beta, IL-6 and TNF-alpha in bovine samples. Vet Immunol Immunopathol. 2007;118:40-9 pubmed
image
image 1 :
Bio-Rad MCA1658 image 1
Published customer image: . Rabbit anti Sheep interleukin 1 antibody ( AHP423 ) used for the detection of bound interleukin 1 from lamb sera in an ELISA using Mouse anti Sheep IL-1&beta antibody, clone 1D4 as a capture antibody ( MCA1658 ). For IL-6, capture is with Mouse anti Sheep IL-6 antibody, clone 4B6 ( MCA1659 ) and detection using Rabbit anti Sheep IL-6 antibody ( AHP424 ). Subsequent visualisation uses HRP conjugated Goat anti Rabbit IgG in both cases. Image caption: . Systemic and diaphragm cytokine responses. Plasma IL-1 (A) and IL-6 (B) protein content. Values are mean SEM. Diaphragm IL-1 (C) and IL-6 (D) mRNA expression. Values are median (with 10th and 90th centiles). * p 0.05 compared to Sal/Sal; # p 0.05 compared to Sal/LPS. From: Karisnan K, Bakker AJ, Song Y, Noble PB, Pillow JJ, et al. (2015). Interleukin-1 Receptor Antagonist Protects against Lipopolysaccharide Induced Diaphragm Weakness in Preterm Lambs. PLoS ONE 10(4): e0124390 .
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA1658
Description :
Mouse anti Sheep Interleukin-1 beta
Specificity :
IL-1 Beta
TargetSpecies :
Sheep
Host :
Mouse
Format :
Purified
Isotypes :
IgG1
Applications :
WB,F,E,C
ApplicationTypes :
Western Blotting,Flow Cytometry,ELISA,Immunohistology - Frozen
Cross Reactivities :
Goat,Bovine,Horse
Clone :
1D4
Quantity :
0.25 mg
Quantity Value :
0.25
Quantity Type :
mg
GO Accessions :
GO:0001660,GO:0005125,GO:0005149,GO:0005615,GO:0006955,GO:0008083,GO:0051781
GOTerms :
fever generation,cytokine activity,interleukin-1 receptor binding,extracellular space,immune response,growth factor activity,positive regulation of cell division
Uniprot Accessions :
P21621
Gene :
IL-1B
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=443539
Entity Formats :
Purified
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
294
PriceEUR :
411
PriceUSD :
411 USD
PriceCHF :
447
PriceSEK :
4480
PriceNOK :
4502
PriceDKK :
3064
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.