product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Human CD3
catalog :
MCA1477
quantity :
0.2 mg
price :
384 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
CD3-12
reactivity :
African green monkey, crab eating macaque, human, mouse, dogs, pigs , cat, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 97
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:300; loading ...; fig 2e
Paldor M, Levkovitch Siany O, Eidelshtein D, Adar R, Enk C, Marmary Y, et al. Single-cell transcriptomics reveals a senescence-associated IL-6/CCR6 axis driving radiodermatitis. EMBO Mol Med. 2022;14:e15653 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:150; loading ...; fig 1f
Rajendran R, Rajendran V, Giraldo Velasquez M, Megalofonou F, Gurski F, Stadelmann C, et al. Oligodendrocyte-Specific Deletion of FGFR1 Reduces Cerebellar Inflammation and Neurodegeneration in MOG35-55-Induced EAE. Int J Mol Sci. 2021;22: pubmed publisher
  • immunohistochemistry; crab eating macaque; 1:600; loading ...; fig s5e
Li D, Edwards R, Manne K, Martinez D, Schäfer A, Alam S, et al. In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell. 2021;184:4203-4219.e32 pubmed publisher
  • immunohistochemistry; mouse; 1:150; loading ...; fig 4a
Kamali S, Rajendran R, Stadelmann C, Karnati S, Rajendran V, Giraldo Velasquez M, et al. Oligodendrocyte-specific deletion of FGFR2 ameliorates MOG35-55 -induced EAE through ERK and Akt signalling. Brain Pathol. 2021;31:297-311 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s1
Asare Y, Koehncke J, Selle J, Simsekyilmaz S, Jankowski J, Shagdarsuren G, et al. Differential Role for Activating FcγRIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis in Apolipoprotein E-Deficient Mice. Front Physiol. 2020;11:673 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 5b
Canon J, Rex K, Saiki A, Mohr C, Cooke K, Bagal D, et al. The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity. Nature. 2019;575:217-223 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:300; loading ...; fig 1a
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 1a
Wirsching H, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino P, et al. Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma. JCI Insight. 2019;4: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 4b
Garcia Agudo L, Janova H, Sendler L, Arinrad S, Steixner A, Hassouna I, et al. Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion. FASEB J. 2019;33:8634-8647 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1b
Perry C, Muñoz Rojas A, Meeth K, Kellman L, Amezquita R, Thakral D, et al. Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. J Exp Med. 2018;215:877-893 pubmed publisher
  • flow cytometry; dogs; loading ...; fig 5
Ito D, Childress M, Mason N, Winter A, O BRIEN T, Henson M, et al. A double blinded, placebo-controlled pilot study to examine reduction of CD34 +/CD117 +/CD133 + lymphoma progenitor cells and duration of remission induced by neoadjuvant valspodar in dogs with large B-cell lymphoma. F1000Res. 2015;4:42 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1c
Berghoff S, Gerndt N, Winchenbach J, Stumpf S, Hosang L, Odoardi F, et al. Dietary cholesterol promotes repair of demyelinated lesions in the adult brain. Nat Commun. 2017;8:14241 pubmed publisher
  • flow cytometry; mouse; 1:200; fig 2
Sommer A, Fadler T, Dorfmeister E, Hoffmann A, Xiang W, Winner B, et al. Infiltrating T lymphocytes reduce myeloid phagocytosis activity in synucleinopathy model. J Neuroinflammation. 2016;13:174 pubmed publisher
  • flow cytometry; mouse; fig 6e
Casella G, Garzetti L, Gatta A, Finardi A, Maiorino C, Ruffini F, et al. IL4 induces IL6-producing M2 macrophages associated to inhibition of neuroinflammation in vitro and in vivo. J Neuroinflammation. 2016;13:139 pubmed publisher
  • immunohistochemistry - paraffin section; pigs ; 1:100; loading ...; fig 1
Bolz M, Ruggli N, Borel N, Pluschke G, Ruf M. Local Cellular Immune Responses and Pathogenesis of Buruli Ulcer Lesions in the Experimental Mycobacterium Ulcerans Pig Infection Model. PLoS Negl Trop Dis. 2016;10:e0004678 pubmed publisher
  • immunocytochemistry; human; fig 3
Heylmann D, Kaina B. The γH2AX DNA damage assay from a drop of blood. Sci Rep. 2016;6:22682 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 6
Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol. 2015;16:1235-44 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 4d
Liao J, Ovenell K, Curtis E, Cecil D, Koehnlein M, Rastetter L, et al. Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer. J Immunother Cancer. 2015;3:16 pubmed publisher
  • immunohistochemistry; human
de Winde C, Zuidscherwoude M, Vasaturo A, van der Schaaf A, Figdor C, van Spriel A. Multispectral imaging reveals the tissue distribution of tetraspanins in human lymphoid organs. Histochem Cell Biol. 2015;144:133-46 pubmed publisher
  • flow cytometry; human; fig 7
Rodriguez J, Marchicio J, López M, Ziblat A, Elias F, Fló J, et al. PyNTTTTGT and CpG immunostimulatory oligonucleotides: effect on granulocyte/monocyte colony-stimulating factor (GM-CSF) secretion by human CD56+ (NK and NKT) cells. PLoS ONE. 2015;10:e0117484 pubmed publisher
  • flow cytometry; domestic rabbit; fig 8
Boutard B, Vankerckhove S, Markine Goriaynoff N, Sarlet M, Desmecht D, McFadden G, et al. The α2,3-sialyltransferase encoded by myxoma virus is a virulence factor that contributes to immunosuppression. PLoS ONE. 2015;10:e0118806 pubmed publisher
  • immunohistochemistry - paraffin section; African green monkey
Kwun J, Page E, Hong J, GIBBY A, Yoon J, Farris A, et al. Neutralizing BAFF/APRIL with atacicept prevents early DSA formation and AMR development in T cell depletion induced nonhuman primate AMR model. Am J Transplant. 2015;15:815-22 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 2
Kobayashi T, Hamaguchi Y, Hasegawa M, Fujimoto M, Takehara K, Matsushita T. B cells promote tumor immunity against B16F10 melanoma. Am J Pathol. 2014;184:3120-9 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
de Bock L, Somers K, Fraussen J, Hendriks J, van Horssen J, Rouwette M, et al. Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis. J Immunol. 2014;193:2147-56 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Schirmer L, Srivastava R, Kalluri S, Böttinger S, Herwerth M, Carassiti D, et al. Differential loss of KIR4.1 immunoreactivity in multiple sclerosis lesions. Ann Neurol. 2014;75:810-28 pubmed publisher
  • immunohistochemistry; dogs; 1:50
Rossi G, Pengo G, Caldin M, Palumbo Piccionello A, Steiner J, Cohen N, et al. Comparison of microbiological, histological, and immunomodulatory parameters in response to treatment with either combination therapy with prednisone and metronidazole or probiotic VSL#3 strains in dogs with idiopathic inflammatory bowel disease. PLoS ONE. 2014;9:e94699 pubmed publisher
  • immunohistochemistry; mouse
Cochain C, Chaudhari S, Koch M, Wiendl H, Eckstein H, Zernecke A. Programmed cell death-1 deficiency exacerbates T cell activation and atherogenesis despite expansion of regulatory T cells in atherosclerosis-prone mice. PLoS ONE. 2014;9:e93280 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Chan I, Jain R, Tessmer M, Gorman D, Mangadu R, Sathe M, et al. Interleukin-23 is sufficient to induce rapid de novo gut tumorigenesis, independent of carcinogens, through activation of innate lymphoid cells. Mucosal Immunol. 2014;7:842-56 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Puentes F, van der Star B, Victor M, Kipp M, Beyer C, Peferoen Baert R, et al. Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis. J Neuroinflammation. 2013;10:118 pubmed publisher
  • immunocytochemistry; cat
Gilroy C, Forzán M, Drew A, Vernau W. Eosinophilia in a cat with acute leukemia. Can Vet J. 2011;52:1004-8 pubmed
  • immunocytochemistry; mouse
Kremer M, Henn A, Kolb C, Basler M, Moebius J, Guillaume B, et al. Reduced immunoproteasome formation and accumulation of immunoproteasomal precursors in the brains of lymphocytic choriomeningitis virus-infected mice. J Immunol. 2010;185:5549-60 pubmed publisher
Pampusch M, Abdelaal H, Cartwright E, Molden J, Davey B, Sauve J, et al. CAR/CXCR5-T cell immunotherapy is safe and potentially efficacious in promoting sustained remission of SIV infection. PLoS Pathog. 2022;18:e1009831 pubmed publisher
Ogrodnik M, Evans S, Fielder E, Victorelli S, Krüger P, Salmonowicz H, et al. Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice. Aging Cell. 2021;20:e13296 pubmed publisher
Srivastava S, Furlan S, Jaeger Ruckstuhl C, Sarvothama M, Berger C, Smythe K, et al. Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade. Cancer Cell. 2021;39:193-208.e10 pubmed publisher
Koppejan H, Jansen D, Hameetman M, Thomas R, Toes R, van Gaalen F. Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis. Arthritis Res Ther. 2019;21:3 pubmed publisher
Magi G, Mariotti F, Berardi S, Piccinini A, Vullo C, Palumbo Piccionello A, et al. Loss of alpha-smooth muscle actin expression associated with chronic intestinal pseudo-obstruction in a young Miniature Bull Terrier. Acta Vet Scand. 2018;60:25 pubmed publisher
Haran K, Hajduczki A, Pampusch M, Mwakalundwa G, Vargas Inchaustegui D, Rakasz E, et al. Simian Immunodeficiency Virus (SIV)-Specific Chimeric Antigen Receptor-T Cells Engineered to Target B Cell Follicles and Suppress SIV Replication. Front Immunol. 2018;9:492 pubmed publisher
Janova H, Arinrad S, Balmuth E, Mitjans M, Hertel J, Habes M, et al. Microglia ablation alleviates myelin-associated catatonic signs in mice. J Clin Invest. 2018;128:734-745 pubmed publisher
Galler A, Rütgen B, Haas E, Saalmuller A, Hirt R, Gerner W, et al. Immunophenotype of Peripheral Blood Lymphocytes in Dogs with Inflammatory Bowel Disease. J Vet Intern Med. 2017;31:1730-1739 pubmed publisher
Akkaya M, Akkaya B, Sheehan P, Miozzo P, Pena M, Qi C, et al. T cell-dependent antigen adjuvanted with DOTAP-CpG-B but not DOTAP-CpG-A induces robust germinal center responses and high affinity antibodies in mice. Eur J Immunol. 2017;47:1890-1899 pubmed publisher
Silveira E, Rogers K, Gumber S, Amancha P, Xiao P, Woollard S, et al. Immune Cell Dynamics in Rhesus Macaques Infected with a Brazilian Strain of Zika Virus. J Immunol. 2017;199:1003-1011 pubmed publisher
Roth Walter F, Bergmayr C, Meitz S, Buchleitner S, Stremnitzer C, Fazekas J, et al. Janus-faced Acrolein prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposure. Sci Rep. 2017;7:45067 pubmed publisher
Wolf Y, Shemer A, Polonsky M, Gross M, Mildner A, Yona S, et al. Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation. J Exp Med. 2017;214:905-917 pubmed publisher
Pfaender S, Walter S, Grabski E, Todt D, Bruening J, Romero Brey I, et al. Immune protection against reinfection with nonprimate hepacivirus. Proc Natl Acad Sci U S A. 2017;114:E2430-E2439 pubmed publisher
Lukas D, Yogev N, Kel J, Regen T, Mufazalov I, Tang Y, et al. TGF-β inhibitor Smad7 regulates dendritic cell-induced autoimmunity. Proc Natl Acad Sci U S A. 2017;114:E1480-E1489 pubmed publisher
Morawski P, Qi C, Bolland S. Non-pathogenic tissue-resident CD8+ T cells uniquely accumulate in the brains of lupus-prone mice. Sci Rep. 2017;7:40838 pubmed publisher
Vogel A, Knier B, Lammens K, Kalluri S, Kuhlmann T, Bennett J, et al. Deletional tolerance prevents AQP4-directed autoimmunity in mice. Eur J Immunol. 2017;47:458-469 pubmed publisher
Ye T, Zhen J, Du Y, Zhou J, Peng A, Vaziri N, et al. Green tea polyphenol (-)-epigallocatechin-3-gallate restores Nrf2 activity and ameliorates crescentic glomerulonephritis. PLoS ONE. 2015;10:e0119543 pubmed publisher
Haas E, Rütgen B, Gerner W, Richter B, Tichy A, Galler A, et al. Phenotypic characterization of canine intestinal intraepithelial lymphocytes in dogs with inflammatory bowel disease. J Vet Intern Med. 2014;28:1708-15 pubmed publisher
Jurk D, Wilson C, Passos J, Oakley F, Correia Melo C, Greaves L, et al. Chronic inflammation induces telomere dysfunction and accelerates ageing in mice. Nat Commun. 2014;2:4172 pubmed publisher
Meeker S, Seamons A, Paik J, Treuting P, Brabb T, Grady W, et al. Increased dietary vitamin D suppresses MAPK signaling, colitis, and colon cancer. Cancer Res. 2014;74:4398-408 pubmed publisher
Koch Hansen L, Sevelsted Møller L, Rabjerg M, Larsen D, Hansen T, Klinge L, et al. Expression of T-cell KV1.3 potassium channel correlates with pro-inflammatory cytokines and disease activity in ulcerative colitis. J Crohns Colitis. 2014;8:1378-91 pubmed publisher
Athwal T, Huang W, Mukherjee R, Latawiec D, Chvanov M, Clarke R, et al. Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell death. Cell Death Dis. 2014;5:e1165 pubmed publisher
Luebben S, Kawabata T, Johnson C, O Sullivan M, Shima N. A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression. Nucleic Acids Res. 2014;42:5605-15 pubmed publisher
Gaffal E, Jakobs M, Glodde N, Schröder R, Kostenis E, Tüting T. ?-arrestin 2 inhibits proinflammatory chemokine production and attenuates contact allergic inflammation in the skin. J Invest Dermatol. 2014;134:2131-2137 pubmed publisher
Olsen L, Boysen P, Akesson C, Gunnes G, Connelley T, Storset A, et al. Characterization of NCR1+ cells residing in lymphoid tissues in the gut of lambs indicates that the majority are NK cells. Vet Res. 2013;44:109 pubmed publisher
Barletta B, Rossi G, Schiavi E, Butteroni C, Corinti S, Boirivant M, et al. Probiotic VSL#3-induced TGF-? ameliorates food allergy inflammation in a mouse model of peanut sensitization through the induction of regulatory T cells in the gut mucosa. Mol Nutr Food Res. 2013;57:2233-44 pubmed publisher
Gaffal E, Cron M, Glodde N, Tuting T. Anti-inflammatory activity of topical THC in DNFB-mediated mouse allergic contact dermatitis independent of CB1 and CB2 receptors. Allergy. 2013;68:994-1000 pubmed publisher
Hargis A, Myers S, Gortel K, Duclos D, Randolph Habecker J. Proliferative, lymphocytic, infundibular mural folliculitis and dermatitis with prominent follicular apoptosis and parakeratotic casts in four Labrador retrievers: preliminary description and response to therapy. Vet Dermatol. 2013;24:346-54, e76-7 pubmed publisher
Billich A, Baumruker T, Beerli C, Bigaud M, Bruns C, Calzascia T, et al. Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis. PLoS ONE. 2013;8:e59630 pubmed publisher
Beachy S, Onozawa M, Silverman D, Chung Y, Rivera M, Aplan P. Isolated Hoxa9 overexpression predisposes to the development of lymphoid but not myeloid leukemia. Exp Hematol. 2013;41:518-529.e5 pubmed publisher
Cardinal H, Dieudé M, Brassard N, Qi S, Patey N, Soulez M, et al. Antiperlecan antibodies are novel accelerators of immune-mediated vascular injury. Am J Transplant. 2013;13:861-874 pubmed publisher
Xie C, Du Y, Kumar K, Li L, Han J, Liu K, et al. Lupus-prone strains vary in susceptibility to antibody-mediated end organ disease. Genes Immun. 2013;14:170-8 pubmed publisher
Depboylu C, Stricker S, Ghobril J, Oertel W, Priller J, Höglinger G. Brain-resident microglia predominate over infiltrating myeloid cells in activation, phagocytosis and interaction with T-lymphocytes in the MPTP mouse model of Parkinson disease. Exp Neurol. 2012;238:183-91 pubmed publisher
Zeybel M, Hardy T, Wong Y, Mathers J, Fox C, Gackowska A, et al. Multigenerational epigenetic adaptation of the hepatic wound-healing response. Nat Med. 2012;18:1369-77 pubmed
Beachy S, Onozawa M, Chung Y, Slape C, Bilke S, Francis P, et al. Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines, and peripheral T-cell lymphoma. Blood. 2012;120:1048-59 pubmed publisher
Koulmanda M, Bhasin M, AWDEH Z, Qipo A, Fan Z, Hanidziar D, et al. The role of TNF-? in mice with type 1- and 2- diabetes. PLoS ONE. 2012;7:e33254 pubmed publisher
Mandolesi G, Grasselli G, Musella A, Gentile A, Musumeci G, Sepman H, et al. GABAergic signaling and connectivity on Purkinje cells are impaired in experimental autoimmune encephalomyelitis. Neurobiol Dis. 2012;46:414-24 pubmed publisher
Zeng M, Southern P, Reilly C, Beilman G, Chipman J, Schacker T, et al. Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy. PLoS Pathog. 2012;8:e1002437 pubmed publisher
Koenders M, Marijnissen R, Joosten L, Abdollahi Roodsaz S, Di Padova F, van de Loo F, et al. T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4Ig but is successfully treated by interleukin-17 neutralization. Arthritis Rheum. 2012;64:1762-70 pubmed publisher
Fava R, Kennedy S, Wood S, Bolstad A, Bienkowska J, Papandile A, et al. Lymphotoxin-beta receptor blockade reduces CXCL13 in lacrimal glands and improves corneal integrity in the NOD model of Sjögren's syndrome. Arthritis Res Ther. 2011;13:R182 pubmed publisher
McPhee C, Sproule T, Shin D, Bubier J, Schott W, Steinbuck M, et al. MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis. J Immunol. 2011;187:4695-704 pubmed publisher
Hvilsted Nielsen H, Toft Hansen H, Lambertsen K, Owens T, Finsen B. Stimulation of adult oligodendrogenesis by myelin-specific T cells. Am J Pathol. 2011;179:2028-41 pubmed publisher
van Roeyen C, Eitner F, Boor P, Moeller M, Raffetseder U, Hanssen L, et al. Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-D. Kidney Int. 2011;80:1292-305 pubmed publisher
Meng J, Mostaghel E, Vakar Lopez F, Montgomery B, True L, Nelson P. Testosterone regulates tight junction proteins and influences prostatic autoimmune responses. Horm Cancer. 2011;2:145-56 pubmed publisher
Xu H, Sandor M, Qi S, Lombardi J, Connor J, McQuillan D, et al. Implantation of a porcine acellular dermal graft in a primate model of rotator cuff repair. J Shoulder Elbow Surg. 2012;21:580-8 pubmed publisher
Wiessner C, Wiederhold K, Tissot A, Frey P, Danner S, Jacobson L, et al. The second-generation active A? immunotherapy CAD106 reduces amyloid accumulation in APP transgenic mice while minimizing potential side effects. J Neurosci. 2011;31:9323-31 pubmed publisher
Johnston C, Manning C, Hernady E, Reed C, Thurston S, Finkelstein J, et al. Effect of total body irradiation on late lung effects: hidden dangers. Int J Radiat Biol. 2011;87:902-13 pubmed publisher
Peng A, Ye T, Rakheja D, Tu Y, Wang T, Du Y, et al. The green tea polyphenol (-)-epigallocatechin-3-gallate ameliorates experimental immune-mediated glomerulonephritis. Kidney Int. 2011;80:601-11 pubmed publisher
Foryst Ludwig A, Hartge M, Clemenz M, Sprang C, Hess K, Marx N, et al. PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice. Cardiovasc Diabetol. 2010;9:64 pubmed publisher
Landsberg J, Gaffal E, Cron M, Kohlmeyer J, Renn M, Tüting T. Autochthonous primary and metastatic melanomas in Hgf-Cdk4 R24C mice evade T-cell-mediated immune surveillance. Pigment Cell Melanoma Res. 2010;23:649-60 pubmed publisher
Canale Zambrano J, Auger M, Haston C. Toll-like receptor-4 genotype influences the survival of cystic fibrosis mice. Am J Physiol Gastrointest Liver Physiol. 2010;299:G381-90 pubmed publisher
Mydel P, Wang Z, Brisslert M, Hellvard A, Dahlberg L, Hazen S, et al. Carbamylation-dependent activation of T cells: a novel mechanism in the pathogenesis of autoimmune arthritis. J Immunol. 2010;184:6882-90 pubmed publisher
Treuting P, Albertson T, Preston B. Case series: acute tumor lysis syndrome in mutator mice with disseminated lymphoblastic lymphoma. Toxicol Pathol. 2010;38:476-85 pubmed publisher
Xu H, Wan H, Zuo W, Sun W, Owens R, Harper J, et al. A porcine-derived acellular dermal scaffold that supports soft tissue regeneration: removal of terminal galactose-alpha-(1,3)-galactose and retention of matrix structure. Tissue Eng Part A. 2009;15:1807-19 pubmed publisher
Aharonowiz M, Einstein O, Fainstein N, Lassmann H, Reubinoff B, Ben Hur T. Neuroprotective effect of transplanted human embryonic stem cell-derived neural precursors in an animal model of multiple sclerosis. PLoS ONE. 2008;3:e3145 pubmed publisher
Sandor M, Xu H, Connor J, Lombardi J, Harper J, Silverman R, et al. Host response to implanted porcine-derived biologic materials in a primate model of abdominal wall repair. Tissue Eng Part A. 2008;14:2021-31 pubmed publisher
Xu H, Wan H, Sandor M, Qi S, Ervin F, Harper J, et al. Host response to human acellular dermal matrix transplantation in a primate model of abdominal wall repair. Tissue Eng Part A. 2008;14:2009-19 pubmed publisher
Jung D, Kim E, Joo S, Park J, Moon C, Kim S, et al. Prolonged survival of islet allografts in mice treated with rosmarinic acid and anti-CD154 antibody. Exp Mol Med. 2008;40:1-10 pubmed
Liu Y, Chen Y, Liu F, Lamb J, Tam P. Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation. Transpl Int. 2008;21:483-94 pubmed publisher
Ramsey M, Krishnamurthy J, Pei X, Torrice C, Lin W, Carrasco D, et al. Expression of p16Ink4a compensates for p18Ink4c loss in cyclin-dependent kinase 4/6-dependent tumors and tissues. Cancer Res. 2007;67:4732-41 pubmed
Dimova T, Mihaylova A, Spassova P, Georgieva R. Establishment of the porcine epitheliochorial placenta is associated with endometrial T-cell recruitment. Am J Reprod Immunol. 2007;57:250-61 pubmed
Xie C, Alcaide P, Geisbrecht B, Schneider D, Herrmann M, Preissner K, et al. Suppression of experimental autoimmune encephalomyelitis by extracellular adherence protein of Staphylococcus aureus. J Exp Med. 2006;203:985-94 pubmed
Zahavy E, Freeman E, Lustig S, Keysary A, Yitzhaki S. Double labeling and simultaneous detection of B- and T cells using fluorescent nano-crystal (q-dots) in paraffin-embedded tissues. J Fluoresc. 2005;15:661-5 pubmed
Faber M, Bette M, Preuss M, Pulmanausahakul R, Rehnelt J, Schnell M, et al. Overexpression of tumor necrosis factor alpha by a recombinant rabies virus attenuates replication in neurons and prevents lethal infection in mice. J Virol. 2005;79:15405-16 pubmed
Saalmuller A, Lunney J, Daubenberger C, Davis W, Fischer U, Göbel T, et al. Summary of the animal homologue section of HLDA8. Cell Immunol. 2005;236:51-8 pubmed
Schupp D, Huck B, Sykora J, Flechtenmacher C, Gorenflo M, Koch A, et al. Right ventricular expression of extracellular matrix proteins, matrix-metalloproteinases, and their inhibitors over a period of 3 years after heart transplantation. Virchows Arch. 2006;448:184-94 pubmed
Lee E, Leng L, Lee V, Trojanowski J. Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis. FEBS Lett. 2005;579:2564-8 pubmed
image
image 1 :
Bio-Rad MCA1477 image 1
Figure A. RPE conjugated Mouse anti Human CD8 ( MCA1226PE ) and Alexa Fluor 647 conjugated Rat IgG1 isotype control ( MCA6004A647 ). Figure B. RPE conjugated Mouse anti Human CD8 ( MCA1226PE ) and Alexa Fluor 647 conjugated Rat anti Human CD3 ( MCA1477A647 ). All experiments performed on red cell lysed human peripheral blood gated on leukocytes in the presence of human SeroBlock ( BUF070A ).
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA1477
Description :
Rat anti Human CD3
Specificity :
CD3
TargetSpecies :
Human
Host :
Rat
Format :
Purified
Isotypes :
IgG1
Applications :
WB,P,IF,F,C
ApplicationTypes :
Western Blotting,Immunohistology - Paraffin,Immunofluorescence,Flow Cytometry,Immunohistology - Frozen
Cross Reactivities :
Bovine,Dog,Horse,Rhesus Monkey,Pig,Chicken,Mouse,Duck,Koala,Harbour Porpoise,Alpaca,Cynomolgus monkey,Spotted Hyena,Sea Lion,Cat,Amazon Parrot,Mammals,Birds,Raccoon,Great horned owl (Bubo virginianus),Bullfrog,Xenopus,Amphibia,Rabbit,African green monkey
Clone :
CD3-12
Quantity :
0.2 mg
Quantity Value :
0.2
Quantity Type :
mg
GO Accessions :
GO:0004888,GO:0005057,GO:0005887,GO:0007172,GO:0007186,GO:0009897,GO:0017124,GO:0019901,GO:0030159,GO:0031295,GO:0042608,GO:0046982,GO:0050852
GOTerms :
transmembrane receptor activity,receptor signaling protein activity,integral to plasma membrane,signal complex assembly,G-protein coupled receptor protein signaling pathway,external side of plasma membrane,SH3 domain binding,protein kinase binding,receptor signaling complex scaffold activity,T cell costimulation,T cell receptor binding,protein heterodimerization activity,T cell receptor signaling pathway
Uniprot Accessions :
P07766
Gene :
CD3E
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=916
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,FITC,Pacific Blue®,Purified
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
274
PriceEUR :
384
PriceUSD :
384 USD
PriceCHF :
418
PriceSEK :
4378
PriceNOK :
4371
PriceDKK :
2864
more info or order :
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.