product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Mouse CD204
catalog :
MCA1322
quantity :
0.25 mg
price :
372 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
2F8
reactivity :
mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:100; loading ...; fig 4j
Wolfsberger J, Sakil H, Zhou L, van Bree N, Baldisseri E, de Souza Ferreira S, et al. TAp73 represses NF-κB-mediated recruitment of tumor-associated macrophages in breast cancer. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 5g
Aarts S, Seijkens T, Kusters P, Van Tiel C, Reiche M, den Toom M, et al. Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis. J Pathol. 2019;247:471-480 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 7m
Koronyo Y, Salumbides B, Sheyn J, Pelissier L, Li S, Ljubimov V, et al. Therapeutic effects of glatiramer acetate and grafted CD115⁺ monocytes in a mouse model of Alzheimer's disease. Brain. 2015;138:2399-422 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 20 ug/ml
Almholt K, Lærum O, Nielsen B, Lund I, Lund L, Rømer J, et al. Spontaneous lung and lymph node metastasis in transgenic breast cancer is independent of the urokinase receptor uPAR. Clin Exp Metastasis. 2015;32:543-54 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100
Meraz I, Savage D, Segura Ibarra V, Li J, Rhudy J, Gu J, et al. Adjuvant cationic liposomes presenting MPL and IL-12 induce cell death, suppress tumor growth, and alter the cellular phenotype of tumors in a murine model of breast cancer. Mol Pharm. 2014;11:3484-91 pubmed publisher
  • immunohistochemistry; mouse; 1:50
Meraz I, Hearnden C, Liu X, Yang M, Williams L, Savage D, et al. Multivalent presentation of MPL by porous silicon microparticles favors T helper 1 polarization enhancing the anti-tumor efficacy of doxorubicin nanoliposomes. PLoS ONE. 2014;9:e94703 pubmed publisher
Ishikawa Y, Gohda T, Tanimoto M, Omote K, Furukawa M, Yamaguchi S, et al. Effect of exercise on kidney function, oxidative stress, and inflammation in type 2 diabetic KK-A(y) mice. Exp Diabetes Res. 2012;2012:702948 pubmed publisher
Hald A, Rønø B, Melander M, Ding M, Holck S, Lund L. MMP9 is protective against lethal inflammatory mass lesions in the mouse colon. Dis Model Mech. 2011;4:212-27 pubmed publisher
Santos A, Martín Oliva D, Ferrer Martín R, Tassi M, Calvente R, Sierra A, et al. Microglial response to light-induced photoreceptor degeneration in the mouse retina. J Comp Neurol. 2010;518:477-92 pubmed publisher
Kondo Y, Lemere C, Seabrook T. Osteopetrotic (op/op) mice have reduced microglia, no Abeta deposition, and no changes in dopaminergic neurons. J Neuroinflammation. 2007;4:31 pubmed
Herber D, Mercer M, Roth L, Symmonds K, Maloney J, Wilson N, et al. Microglial activation is required for Abeta clearance after intracranial injection of lipopolysaccharide in APP transgenic mice. J Neuroimmune Pharmacol. 2007;2:222-31 pubmed
Guest C, Hartman M, O Connor J, Chakour K, Sovari A, Freund G. Phagocytosis of cholesteryl ester is amplified in diabetic mouse macrophages and is largely mediated by CD36 and SR-A. PLoS ONE. 2007;2:e511 pubmed
Herber D, Maloney J, Roth L, Freeman M, Morgan D, Gordon M. Diverse microglial responses after intrahippocampal administration of lipopolysaccharide. Glia. 2006;53:382-91 pubmed
DeVries Seimon T, Li Y, Yao P, Stone E, Wang Y, Davis R, et al. Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor. J Cell Biol. 2005;171:61-73 pubmed
Hoffmann P, deCathelineau A, Ogden C, Leverrier Y, Bratton D, Daleke D, et al. Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells. J Cell Biol. 2001;155:649-59 pubmed
image
image 1 :
Bio-Rad MCA1322 image 1
Staining of mouse peritoneal macrophages with Rat anti Mouse CD204:FITC (MCA1322FB)
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA1322
Description :
Rat anti Mouse CD204
Specificity :
CD204
TargetSpecies :
Mouse
Host :
Rat
Format :
Purified
Isotypes :
IgG2b
Applications :
WB,P,IP,F,C,E,RE
ApplicationTypes :
Western Blotting,Immunohistology - Paraffin,Immunoprecipitation,Flow Cytometry,Immunohistology - Frozen,ELISA,Immunohistology - Resin
Cross Reactivities :
Pig,Channel catfish
Clone :
2F8
Quantity :
0.25 mg
Quantity Value :
0.25
Quantity Type :
mg
GO Accessions :
GO:0005515,GO:0016021,GO:0005044,GO:0006898,GO:0010744,GO:0010886,GO:0030169,GO:0030301,GO:0034362,GO:0034381,GO:0042953
GOTerms :
protein binding,integral to membrane,scavenger receptor activity,receptor-mediated endocytosis,positive regulation of macrophage derived foam cell differentiation,positive regulation of cholesterol storage,low-density lipoprotein particle binding,cholesterol transport,low-density lipoprotein particle,plasma lipoprotein particle clearance,lipoprotein transport
Uniprot Accessions :
P30204
Gene :
Msr1
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=20288
Published Synonyms :
Scavenger Receptor Type I/II
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,Biotin,FITC,Low Endotoxin,Purified,RPE,Alexa Fluor® 700
UNSPSC :
41116161
Concentration :
IgG concentration 1.0 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
266
PriceEUR :
372
PriceUSD :
372 USD
PriceCHF :
405
PriceSEK :
4055
PriceNOK :
4075
PriceDKK :
2774
more info or order :
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.