product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rat anti Mouse CD45
catalog :
MCA1031GA
quantity :
0.1 mg
price :
249 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
YW62.3
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
Bio-Rad product webpage
citations: 5
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 3a-b, 6e-f
Martinez L, Garcia G, Contreras D, Gong D, Sun R, Arumugaswami V. Zika Virus Mucosal Infection Provides Protective Immunity. J Virol. 2020;94: pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 2
Kim J, Phan T, Nguyen V, Dinh Vu H, Zheng J, Yun M, et al. Salmonella typhimurium Suppresses Tumor Growth via the Pro-Inflammatory Cytokine Interleukin-1β. Theranostics. 2015;5:1328-42 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Kan M, Lee J, Wilson J, Everhart A, Brown C, Hoofnagle A, et al. Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease. J Neurosci. 2015;35:5969-82 pubmed publisher
Zhou Z, Bachstetter A, Späni C, Roy S, Watterson D, Van Eldik L. Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes. J Neuroinflammation. 2017;14:75 pubmed publisher
Dong C, Greathouse K, Beacham R, Palladino S, Helton E, Ubogu E. Fibronectin connecting segment-1 peptide inhibits pathogenic leukocyte trafficking and inflammatory demyelination in experimental models of chronic inflammatory demyelinating polyradiculoneuropathy. Exp Neurol. 2017;292:35-45 pubmed publisher
image
image 1 :
Bio-Rad MCA1031GA image 1
Figure A. Alexa488® conjugated rat anti mouse CD3 ( MCA2690A488 ) and Alexa647® conjugated Rat IgG2b isotype control ( MCA1125A647 ). Figure B. Alexa488® conjugated rat anti mouse CD3 ( MCA2690A488 ) and Alexa647® conjugated rat anti mouse CD45 ( MCA1031A647 ). All experiments performed on murine splenocytes in the presence of murine SeroBlock (BUF041A).
product information
Entity Type :
Monoclonal Antibody
Entity Category :
Antibodies
ProductCode :
MCA1031GA
Description :
Rat anti Mouse CD45
Specificity :
CD45
TargetSpecies :
Mouse
Host :
Rat
Format :
Purified
Isotypes :
IgG2b
Applications :
IP,F,C,IF
ApplicationTypes :
Immunoprecipitation,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
Clone :
YW62.3
Quantity :
0.1 mg
Quantity Value :
0.1
Quantity Type :
mg
GO Accessions :
GO:0000187,GO:0001915,GO:0001916,GO:0001960,GO:0002925,GO:0051726,GO:0004725,GO:0005887,GO:0005925,GO:0006469,GO:0006470,GO:0007159,GO:0008201,GO:0009897,GO:0019901,GO:0030183,GO:0030890,GO:0031953,GO:0034113,GO:0042098,GO:0042100,GO:0043065,GO:0043395,GO:0043410,GO:0045059,GO:0045060,GO:0045121,GO:0045577,GO:0045588,GO:0046641,GO:0048304,GO:0050732,GO:0050852,GO:0050853,GO:0050855,GO:0050857,GO:0051209,GO:0051607
GOTerms :
activation of MAPK activity,negative regulation of T cell mediated cytotoxicity,positive regulation of T cell mediated cytotoxicity,negative regulation of cytokine-mediated signaling pathway,positive regulation of humoral immune response mediated by circulating immunoglobulin,regulation of cell cycle,protein tyrosine phosphatase activity,integral to plasma membrane,focal adhesion,negative regulation of protein kinase activity,protein dephosphorylation,leukocyte cell-cell adhesion,heparin binding,external side of plasma membrane,protein kinase binding,B cell differentiation,positive regulation of B cell proliferation,negative regulation of protein autophosphorylation,heterotypic cell-cell adhesion,T cell proliferation,B cell proliferation,positive regulation of apoptosis,heparan sulfate proteoglycan binding,positive regulation of MAPKKK cascade,positive thymic T cell selection,negative thymic T cell selection,membrane raft,regulation of B cell differentiation,positive regulation of gamma-delta T cell differentiation,positive regulation of alpha-beta T cell proliferation,positive regulation of isotype switching to IgG isotypes,negative regulation of peptidyl-tyrosine phosphorylation,T cell receptor signaling pathway,B cell receptor signaling pathway,regulation of B cell receptor signaling pathway,positive regulation of antigen receptor-mediated signaling pathway,release of sequestered calcium ion into cytosol,defense response to virus
Uniprot Accessions :
P06800
Gene :
Ptprc
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=19264
Published Synonyms :
LCA
Entity Formats :
Alexa Fluor® 488,Alexa Fluor® 647,FITC,Purified,RPE,StarBright Blue 700,Amethyst Orange,StarBright Violet 440,StarBright Violet 515,StarBright Violet 610,StarBright Violet 670,StarBright Violet 475,StarBright UltraViolet 400,StarBright UltraViolet 665,StarBright UltraViolet 795,StarBright Violet 760,StarBright UltraViolet 445,StarBright UltraViolet 510,StarBright UltraViolet 740,StarBright UltraViolet 575,StarBright UltraViolet 605,StarBright Blue 580,StarBright Blue 615,StarBright Blue 675,StarBright Blue 765,StarBright Blue 810,StarBright Yellow 575,StarBright Yellow 605,StarBright Yellow 665,StarBright Yellow 800,StarBright Yellow 720,StarBright Red 670,StarBright Red 715,StarBright Red 775,StarBright Red 815
UNSPSC :
41116161
Concentration :
IgG concentration 1 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
178
PriceEUR :
249
PriceUSD :
249 USD
PriceCHF :
271
PriceSEK :
2714
PriceNOK :
2728
PriceDKK :
1856
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.