product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Sheep anti Human TGN46
catalog :
AHP500GT
quantity :
10 µg
price :
439 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
African green monkey, human
application :
western blot, immunocytochemistry, other
more info or order :
Bio-Rad product webpage
citations: 15
Published Application/Species/Sample/DilutionReference
  • other; human; 1:40; loading ...; fig 9e, s1b
Hess M, Krainer I, Filipek P, Witting B, Gutleben K, Vietor I, et al. Advanced Microscopy for Liver and Gut Ultrastructural Pathology in Patients with MVID and PFIC Caused by MYO5B Mutations. J Clin Med. 2021;10: pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 6c
Zhang X, Jiang S, Mitok K, Li L, Attie A, Martin T. BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells. J Cell Biol. 2017;216:2151-2166 pubmed publisher
  • immunocytochemistry; human; 1:400; loading ...; fig 1a
Patwardhan A, Bardin S, Miserey Lenkei S, Larue L, Goud B, Raposo G, et al. Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes. Nat Commun. 2017;8:15835 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 3B
Miles A, Burr S, Grice G, Nathan J. The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1? prolyl hydroxylation by regulating cellular iron levels. elife. 2017;6: pubmed publisher
  • immunocytochemistry; African green monkey; 1:400; fig 1
  • immunocytochemistry; human; 1:400; fig 2
Pagliuso A, Valente C, Giordano L, Filograna A, Li G, Circolo D, et al. Golgi membrane fission requires the CtBP1-S/BARS-induced activation of lysophosphatidic acid acyltransferase ?. Nat Commun. 2016;7:12148 pubmed publisher
  • immunocytochemistry; human; fig 7
Kajiho H, Kajiho Y, Frittoli E, Confalonieri S, Bertalot G, Viale G, et al. RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs. EMBO Rep. 2016;17:1061-80 pubmed publisher
  • western blot; human; fig 5
Fearnley G, Smith G, Abdul Zani I, Yuldasheva N, Mughal N, Homer Vanniasinkam S, et al. VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis. Biol Open. 2016;5:571-83 pubmed publisher
Hirschenberger M, Lepelley A, Rupp U, Klute S, Hunszinger V, Koepke L, et al. ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling. Nat Commun. 2023;14:6770 pubmed publisher
Morales Paytuv xed F, Fajardo A, Ruiz Mirapeix C, Rae J, Tebar F, Bosch M, et al. Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation. J Cell Biol. 2023;222: pubmed publisher
Uzquiano A, Cifuentes Diaz C, Jabali A, Romero D, Houllier A, Dingli F, et al. Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia. Cell Rep. 2019;28:1596-1611.e10 pubmed publisher
Li C, Huang L, Sun W, Chen Y, He M, Yue J, et al. Saikosaponin D suppresses enterovirus A71 infection by inhibiting autophagy. Signal Transduct Target Ther. 2019;4:4 pubmed publisher
Schnitzbauer J, Wang Y, Zhao S, Bakalar M, Nuwal T, Chen B, et al. Correlation analysis framework for localization-based superresolution microscopy. Proc Natl Acad Sci U S A. 2018;115:3219-3224 pubmed publisher
Brahms A, Mudhasani R, Pinkham C, Kota K, Nasar F, Zamani R, et al. Sorafenib Impedes Rift Valley Fever Virus Egress by Inhibiting Valosin-Containing Protein Function in the Cellular Secretory Pathway. J Virol. 2017;91: pubmed publisher
Gao Y, Liu Y, Hong L, Yang Z, Cai X, Chen X, et al. Golgi-associated LC3 lipidation requires V-ATPase in noncanonical autophagy. Cell Death Dis. 2016;7:e2330 pubmed publisher
Banushi B, Forneris F, Straatman Iwanowska A, Strange A, Lyne A, Rogerson C, et al. Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis. Nat Commun. 2016;7:12111 pubmed publisher
image
image 1 :
Bio-Rad AHP500GT image 1
Published customer image: . Sheep anti Human TGN46 antibody ( AHP500 ) used for the identification of the trans golgi network in MD-MB-231 cells by immunofluorescence. Image caption: . APP redistributes from endosomes to the TGN upon overexpression of μ4-F255A-HA. MD-MB-231 cells were cotransfected with a plasmid encoding either of the indicated HA-epitope-tagged variants of u4, and with a plasmid encoding APP-GFP carrying the double mutation F615P/D664A. After 24-h cells were fixed, permeabilized, stained for EEA1 and TGN46, and examined by fluorescence microscopy. Merging green, red, and blue channels generated the fourth image on each row; yellow indicates overlapping localization of the green and red channels, cyan indicates overlapping localization of the green and blue channels, magenta indicates overlapping localization of the red and blue channels, and white indicates overlapping localization of the red, green, and blue channels. Insets show 2× magnifications. Bar, 10 um. From: Citation: Ross BH, Lin Y, Corales EA, Burgos PV, Mardones GA (2014). Structural and Functional Characterization of Cargo-Binding Sites on the μ4-Subunit of Adaptor Protein Complex 4. PLoS ONE 9(2): e88147 . This image is from an open access article distributed under the terms of the Creative Commons Attribution License .
product information
Entity Type :
Polyclonal Antibody
Entity Category :
Antibodies
ProductCode :
AHP500GT
Description :
Sheep anti Human TGN46
Specificity :
TGN46
TargetSpecies :
Human
Host :
Sheep
Format :
Purified
Isotypes :
Polyclonal IgG
Applications :
WB,C,IF
ApplicationTypes :
Western Blotting,Immunohistology - Frozen,Immunofluorescence
Cross Reactivities :
Primate
Quantity :
10 µg
Quantity Value :
10
Quantity Type :
µg
Uniprot Accessions :
O43493
Gene :
TGOLN2
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10618
Published Synonyms :
TGOLN2
Entity Formats :
Purified,Serum
UNSPSC :
41116161
Concentration :
IgG concentration 0.25 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
313
PriceEUR :
439
PriceUSD :
439 USD
PriceCHF :
478
PriceSEK :
4785
PriceNOK :
4809
PriceDKK :
3273
NotForSaleInCountries :
CA
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.