product summary
Loading...
company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Sheep anti Human TGN46
catalog :
AHP500G
quantity :
25 µg
price :
789 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
African green monkey, human, mouse
application :
western blot, immunocytochemistry, other
more info or order :
Bio-Rad product webpage
citations: 22
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:200; loading ...; fig 4
Butt B, Owen D, Jeffries C, Ivanova L, Hill C, Houghton J, et al. Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex. elife. 2020;9: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 7d
Judith D, Jefferies H, Boeing S, Frith D, Snijders A, Tooze S. ATG9A shapes the forming autophagosome through Arfaptin 2 and phosphatidylinositol 4-kinase IIIβ. J Cell Biol. 2019;218:1634-1652 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s8
Torgersen M, Klokk T, Kavaliauskiene S, Klose C, Simons K, Skotland T, et al. The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport. Oncotarget. 2016;7:86871-86888 pubmed publisher
  • immunocytochemistry; mouse; 1:4000; fig 4
  • other; African green monkey; 1:200; fig 1
  • immunocytochemistry; African green monkey; 1:4000; fig 1
Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher
  • immunocytochemistry; African green monkey; 1:1000; loading ...; fig 5a
Wegel E, Göhler A, Lagerholm B, Wainman A, Uphoff S, Kaufmann R, et al. Imaging cellular structures in super-resolution with SIM, STED and Localisation Microscopy: A practical comparison. Sci Rep. 2016;6:27290 pubmed publisher
  • western blot; human; loading ...; fig 3d
Crevenna A, Blank B, Maiser A, Emin D, Prescher J, Beck G, et al. Secretory cargo sorting by Ca2+-dependent Cab45 oligomerization at the trans-Golgi network. J Cell Biol. 2016;213:305-14 pubmed publisher
  • western blot; human; fig 1
Tenorio M, Ross B, Luchsinger C, Rivera Dictter A, Arriagada C, Acuña D, et al. Distinct Biochemical Pools of Golgi Phosphoprotein 3 in the Human Breast Cancer Cell Lines MCF7 and MDA-MB-231. PLoS ONE. 2016;11:e0154719 pubmed publisher
Nishino M, Imaizumi H, Yokoyama Y, Katahira J, Kimura H, Matsuura N, et al. Histone methyltransferase SUV39H1 regulates the Golgi complex via the nuclear envelope-spanning LINC complex. PLoS ONE. 2023;18:e0283490 pubmed publisher
Saffari A, Brechmann B, Boeger C, Saber W, Jumo H, Whye D, et al. High-Content Small Molecule Screen Identifies a Novel Compound That Restores AP-4-Dependent Protein Trafficking in Neuronal Models of AP-4-Associated Hereditary Spastic Paraplegia. Res Sq. 2023;: pubmed publisher
Wang J, Lau P, Li C, Guo Y. The clathrin adaptor complex-1 and Rab12 regulate post-golgi trafficking of WT epidermal growth factor receptor (EGFR). J Biol Chem. 2023;299:102979 pubmed publisher
Wang Y, Maeda Y, Liu Y, Takada Y, Ninomiya A, Hirata T, et al. Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation. Nat Commun. 2020;11:860 pubmed publisher
Lauritzen I, Bécot A, Bourgeois A, Pardossi Piquard R, Biferi M, Barkats M, et al. Targeting γ-secretase triggers the selective enrichment of oligomeric APP-CTFs in brain extracellular vesicles from Alzheimer cell and mouse models. Transl Neurodegener. 2019;8:35 pubmed publisher
Larocque G, La Borde P, Clarke N, Carter N, Royle S. Tumor protein D54 defines a new class of intracellular transport vesicles. J Cell Biol. 2020;219: pubmed publisher
Gillingham A, Bertram J, Begum F, Munro S. In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation. elife. 2019;8: pubmed publisher
Li J, Tang D, Ireland S, Wang Y. DjA1 maintains Golgi integrity via interaction with GRASP65. Mol Biol Cell. 2019;30:478-490 pubmed publisher
Deng Y, Pakdel M, Blank B, Sundberg E, Burd C, von Blume J. Activity of the SPCA1 Calcium Pump Couples Sphingomyelin Synthesis to Sorting of Secretory Proteins in the Trans-Golgi Network. Dev Cell. 2018;47:464-478.e8 pubmed publisher
Kanatsu K, Hori Y, Ebinuma I, Chiu Y, Tomita T. Retrograde transport of ?-secretase from endosomes to the trans-Golgi network regulates A?42 production. J Neurochem. 2018;: pubmed publisher
Riva L, Song O, Prentoe J, Helle F, L homme L, Gattolliat C, et al. Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry. J Virol. 2018;92: pubmed publisher
Sanders A, Chang K, Zhu X, Thoppil R, Holmes W, Kaverina I. Nonrandom γ-TuNA-dependent spatial pattern of microtubule nucleation at the Golgi. Mol Biol Cell. 2017;28:3181-3192 pubmed publisher
Bussiere R, Lacampagne A, Reiken S, Liu X, Scheuerman V, Zalk R, et al. Amyloid ? production is regulated by ?2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor. J Biol Chem. 2017;292:10153-10168 pubmed publisher
Sugden S, Pham T, Cohen E. HIV-1 Vpu Downmodulates ICAM-1 Expression, Resulting in Decreased Killing of Infected CD4+ T Cells by NK Cells. J Virol. 2017;91: pubmed publisher
Magdeleine M, Gautier R, Gounon P, Barelli H, Vanni S, Antonny B. A filter at the entrance of the Golgi that selects vesicles according to size and bulk lipid composition. elife. 2016;5: pubmed publisher
image
image 1 :
Bio-Rad AHP500G image 1
Published customer image: . Sheep anti Human TGN46 antibody ( AHP500 ) used for the identification of the trans golgi network in MD-MB-231 cells by immunofluorescence. Image caption: . APP redistributes from endosomes to the TGN upon overexpression of μ4-F255A-HA. MD-MB-231 cells were cotransfected with a plasmid encoding either of the indicated HA-epitope-tagged variants of u4, and with a plasmid encoding APP-GFP carrying the double mutation F615P/D664A. After 24-h cells were fixed, permeabilized, stained for EEA1 and TGN46, and examined by fluorescence microscopy. Merging green, red, and blue channels generated the fourth image on each row; yellow indicates overlapping localization of the green and red channels, cyan indicates overlapping localization of the green and blue channels, magenta indicates overlapping localization of the red and blue channels, and white indicates overlapping localization of the red, green, and blue channels. Insets show 2× magnifications. Bar, 10 um. From: Citation: Ross BH, Lin Y, Corales EA, Burgos PV, Mardones GA (2014). Structural and Functional Characterization of Cargo-Binding Sites on the μ4-Subunit of Adaptor Protein Complex 4. PLoS ONE 9(2): e88147 . This image is from an open access article distributed under the terms of the Creative Commons Attribution License .
product information
Entity Type :
Polyclonal Antibody
Entity Category :
Antibodies
ProductCode :
AHP500G
Description :
Sheep anti Human TGN46
Specificity :
TGN46
TargetSpecies :
Human
Host :
Sheep
Format :
Purified
Isotypes :
Polyclonal IgG
Applications :
WB,C,IF
ApplicationTypes :
Western Blotting,Immunohistology - Frozen,Immunofluorescence
Cross Reactivities :
Primate
Quantity :
25 µg
Quantity Value :
25
Quantity Type :
µg
Uniprot Accessions :
O43493
Gene :
TGOLN2
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10618
Published Synonyms :
TGOLN2
Entity Formats :
Purified,Serum
UNSPSC :
41116161
Concentration :
IgG concentration 0.25 mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
563
PriceEUR :
789
PriceUSD :
789 USD
PriceCHF :
858
PriceSEK :
8600
PriceNOK :
8643
PriceDKK :
5883
NotForSaleInCountries :
CA
more info or order :
Bio-Rad product webpage
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.