product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Sheep anti Human TGN46
catalog :
AHP500
quantity :
0.1 ml
price :
439 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; loading ...; fig s1c
Jimenez Orgaz A, Kvainickas A, Nägele H, Denner J, Eimer S, Dengjel J, et al. Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy. EMBO J. 2018;37:235-254 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2d
Stevenson N, Bergen D, Skinner R, Kague E, Martin Silverstone E, Robson Brown K, et al. Giantin-knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression. J Cell Sci. 2017;130:4132-4143 pubmed publisher
  • immunocytochemistry; human; 1:300; loading ...; fig 1c
Wong M, Gillingham A, Munro S. The golgin coiled-coil proteins capture different types of transport carriers via distinct N-terminal motifs. BMC Biol. 2017;15:3 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 7a
Cabukusta B, Kol M, Kneller L, Hilderink A, Bickert A, Mina J, et al. ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain. Sci Rep. 2017;7:41290 pubmed publisher
Madan V, Albacete Albacete L, Jin L, Scaturro P, Watson J, Muschalik N, et al. HEATR5B associates with dynein-dynactin and promotes motility of AP1-bound endosomal membranes. EMBO J. 2023;42:e114473 pubmed publisher
Mamais A, Sanyal A, Fajfer A, Zykoski C, Guldin M, Riley DiPaolo A, et al. The LRRK2 kinase substrates Rab8a and Rab10 contribute complementary but distinct disease-relevant phenotypes in human neurons. bioRxiv. 2023;: pubmed publisher
Ravussin A, Brech A, Tooze S, Stenmark H. The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy. J Cell Sci. 2021;134: pubmed publisher
Zhang X, Wang L, Ireland S, Ahat E, Li J, Bekier Ii M, et al. GORASP2/GRASP55 collaborates with the PtdIns3K UVRAG complex to facilitate autophagosome-lysosome fusion. Autophagy. 2019;:1-14 pubmed publisher
Eisler S, Curado F, Link G, Schulz S, Noack M, Steinke M, et al. A Rho signaling network links microtubules to PKD controlled carrier transport to focal adhesions. elife. 2018;7: pubmed publisher
Hsu R, Zhong C, Wang C, Liao W, Yang C, Lin S, et al. Golgi tethering factor golgin-97 suppresses breast cancer cell invasiveness by modulating NF-κB activity. Cell Commun Signal. 2018;16:19 pubmed publisher
Kirschman J, Qi M, Ding L, Hammonds J, Dienger Stambaugh K, Wang J, et al. HIV-1 Envelope Glycoprotein Trafficking through the Endosomal Recycling Compartment Is Required for Particle Incorporation. J Virol. 2018;92: pubmed publisher
Kvainickas A, Jimenez Orgaz A, Nägele H, Hu Z, Dengjel J, Steinberg F. Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport. J Cell Biol. 2017;216:3677-3693 pubmed publisher
Mana G, Clapero F, Panieri E, Panero V, Böttcher R, Tseng H, et al. PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. Nat Commun. 2016;7:13546 pubmed publisher
Harrison K, Haga I, Pechenick Jowers T, Jasim S, Cintrat J, Gillet D, et al. Vaccinia Virus Uses Retromer-Independent Cellular Retrograde Transport Pathways To Facilitate the Wrapping of Intracellular Mature Virions during Virus Morphogenesis. J Virol. 2016;90:10120-10132 pubmed publisher
image
image 1 :
Bio-Rad AHP500 image 1
Published customer image: . Sheep anti Human TGN46 antibody ( AHP500 ) used for the identification of the trans golgi network in MD-MB-231 cells by immunofluorescence. Image caption: . APP redistributes from endosomes to the TGN upon overexpression of μ4-F255A-HA. MD-MB-231 cells were cotransfected with a plasmid encoding either of the indicated HA-epitope-tagged variants of u4, and with a plasmid encoding APP-GFP carrying the double mutation F615P/D664A. After 24-h cells were fixed, permeabilized, stained for EEA1 and TGN46, and examined by fluorescence microscopy. Merging green, red, and blue channels generated the fourth image on each row; yellow indicates overlapping localization of the green and red channels, cyan indicates overlapping localization of the green and blue channels, magenta indicates overlapping localization of the red and blue channels, and white indicates overlapping localization of the red, green, and blue channels. Insets show 2× magnifications. Bar, 10 um. From: Citation: Ross BH, Lin Y, Corales EA, Burgos PV, Mardones GA (2014). Structural and Functional Characterization of Cargo-Binding Sites on the μ4-Subunit of Adaptor Protein Complex 4. PLoS ONE 9(2): e88147 . This image is from an open access article distributed under the terms of the Creative Commons Attribution License .
product information
Entity Type :
Polyclonal Antibody
Entity Category :
Antibodies
ProductCode :
AHP500
Description :
Sheep anti Human TGN46
Specificity :
TGN46
TargetSpecies :
Human
Host :
Sheep
Format :
Serum
Isotypes :
Polyclonal IgG
Applications :
WB,C,IF
ApplicationTypes :
Western Blotting,Immunohistology - Frozen,Immunofluorescence
Cross Reactivities :
Primate
Quantity :
0.1 ml
Quantity Value :
0.1
Quantity Type :
ml
Uniprot Accessions :
O43493
Gene :
TGOLN2
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10618
Published Synonyms :
TGOLN2
Entity Formats :
Purified,Serum
UNSPSC :
41116161
Product Form :
Serum, diluted - liquid
PriceGBP :
313
PriceEUR :
439
PriceUSD :
439 USD
PriceCHF :
478
PriceSEK :
4785
PriceNOK :
4809
PriceDKK :
3273
NotForSaleInCountries :
CA ,AU ,NZ
more info or order :
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com
1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.