product summary
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company name :
Bio-Rad
other brands :
Biogenesis, Serotec, AbD Serotec, Oxford Biotechnology
product type :
antibody
product name :
Rabbit anti ATG5-ATG12 Complex (C-Terminal)
catalog :
AAM79
quantity :
0.1 mg
price :
1049 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
more info or order :
image
image 1 :
Published customer image: . Rabbit anti ATG5-ATG12 Complex antibody used for the evaluation of ATG5-ATG12 conjugate expression in OVCAR-3 cells following induction of autophagy by western blotting. Image caption: . The time course of autophagy and apoptosis induction by 30 μM resveratrol treatment. A. Live cell imaging by confocal microscopy (with 10X objective) with Cyto-ID dye in OVCAR-3 cells treated with 30 μM resveratrol at 0, 12, 24 and 48 hour time points. B. Live cell imaging by confocal microscopy (with 10X objective) with caspase 3 green detection dye in OVCAR-3 cells at 0, 12, 24 and 48 hour time points. C. OVCAR-3 cells were treated with 30 μM of resveratrol for 12 h, 24 h, and 48 h. Western blotting of total cell lysates were performed with anti-ATG5-ATG12, LC3, and caspase 3 antibodies. No cleavage of ATG5 was observed. The results shown represent an experiment, in which each time-point of treatment was duplicated. From: Lang F, Qin Z, Li F, Zhang H, Fang Z, Hao E (2015) Apoptotic Cell Death Induced by Resveratrol Is Partially Mediated by the Autophagy Pathway in Human Ovarian Cancer Cells. . PLoS ONE 10(6): e0129196 .
product information
Entity Type :
Polyclonal Antibody
Entity Category :
Antibodies
Region :
(C-TERMINAL)
ProductCode :
AAM79
Description :
Rabbit anti ATG5-ATG12 Complex (C-Terminal)
Specificity :
ATG5-ATG12 Complex
TargetSpecies :
Mouse
Host :
Rabbit
Format :
Purified
Isotypes :
Polyclonal IgG
Applications :
WB
ApplicationTypes :
Western Blotting
Cross Reactivities :
Human
Quantity :
0.1 mg
Quantity Value :
0.1
Quantity Type :
mg
GO Accessions :
GO:0000045,GO:0005515,GO:0032480,GO:0034045,GO:0001974,GO:0005829,GO:0005776,GO:0042493,GO:0031397,GO:0042311,GO:0043066,GO:0043687,GO:0048840,GO:0055015,GO:0060047,GO:0006915
GOTerms :
autophagic vacuole assembly,protein binding,negative regulation of type I interferon production,pre-autophagosomal structure membrane,blood vessel remodeling,cytosol,autophagic vacuole,response to drug,negative regulation of protein ubiquitination,vasodilation,negative regulation of apoptosis,post-translational protein modification,otolith development,ventricular cardiac muscle cell development,heart contraction,apoptosis
Uniprot Accessions :
Q99J83,Q9H1Y0,Q9CQY1,O94817
Gene :
ATG12,Atg5,Atg12,ATG5
GeneID URL :
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9140, http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11793, http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=67526, http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9474
Entity Formats :
Purified
UNSPSC :
41116161
Concentration :
IgG concentration 1.0mg/ml
Product Form :
Purified IgG - liquid
PriceGBP :
896
PriceEUR :
1049
PriceUSD :
1049 USD
PriceCHF :
1141
PriceSEK :
11434
PriceNOK :
11491
PriceDKK :
7821
more info or order :
company information
Bio-Rad
Endeavour House, Langford Business Park
Langford Lane, Kidlington
OXON, OX5 1GE
Langford Lane, Kidlington
OXON, OX5 1GE
antibody_sales_uk@bio-rad.com
https://www.bio-rad-antibodies.com1 800 265 7376 (North America)
44 (0)1865 852 700 (Rest of World)
44 (0)1865 852 700 (Rest of World)
headquarters: UK
Bio-Rad is one of the world's leading antibody manufacturers, offering over 12,000 antibodies and related reagents for a focused range of research areas such as immunology, cancer, veterinary research and cell biology through its antibody experts formerly known as AbD Serotec.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.
The range includes apoptosis kits, autophagy reagents, CD markers, epitope tag antibodies, immunology antibodies, neuroscience antibodies, and veterinary reagents.
Bio-Rad has an ISO 9001 and ISO 13485 certified production facility in the United Kingdom as well as ISO 9001 certified facilities in Germany and the United States.
Our expertise extends to traditional and recombinant antibody generation and production services. Our custom generation service delivers antibodies in as little as 8 weeks with greater than 90% success. The in vitro technology enables selection of antibodies to challenging targets, long term consistent supply, and provision of the antibody sequence.
At Bio-Rad we are committed to your success when using our antibodies and we focus on providing the technology, products and all the supporting information you need to excel in your research.