| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 5a
| Reynders M, Matsuura B, Bérouti M, Simoneschi D, Marzio A, Pagano M, et al. PHOTACs enable optical control of protein degradation. Sci Adv. 2020;6:eaay5064 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Basturk O, Weigelt B, Adsay V, Benhamida J, Askan G, Wang L, et al. Sclerosing epithelioid mesenchymal neoplasm of the pancreas - a proposed new entity. Mod Pathol. 2020;33:456-467 pubmed publisher |
- western blot; mouse; loading ...; fig ev3e
| Dey A, Yang W, Gegonne A, Nishiyama A, Pan R, Yagi R, et al. BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses. EMBO J. 2019;38: pubmed publisher |
- immunohistochemistry - paraffin section; human; loading ...; fig 3d
| Zhang P, Wang D, Zhao Y, Ren S, Gao K, Ye Z, et al. Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation. Nat Med. 2017;23:1055-1062 pubmed publisher |
- western blot; mouse; loading ...; fig 7a
| Zhao L, Li J, Fu Y, Zhang M, Wang B, Ouellette J, et al. Photoreceptor protection via blockade of BET epigenetic readers in a murine model of inherited retinal degeneration. J Neuroinflammation. 2017;14:14 pubmed publisher |
- chromatin immunoprecipitation; mouse; fig s1
- immunoprecipitation; mouse; fig s1
- western blot; mouse; 1:2000; fig s1
| Pinz S, Unser S, Rascle A. Signal transducer and activator of transcription STAT5 is recruited to c-Myc super-enhancer. BMC Mol Biol. 2016;17:10 pubmed publisher |
- western blot; mouse; fig 1
| Nakagawa A, Adams C, Huang Y, Hamarneh S, Liu W, Von Alt K, et al. Selective and reversible suppression of intestinal stem cell differentiation by pharmacological inhibition of BET bromodomains. Sci Rep. 2016;6:20390 pubmed publisher |
- western blot; human; fig 3
| Shu S, Lin C, He H, Witwicki R, Tabassum D, Roberts J, et al. Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer. Nature. 2016;529:413-417 pubmed publisher |
| Kang M, Kim J, Ryu E, Ha N, Hwang S, Kim B, et al. PCNA Unloading Is Negatively Regulated by BET Proteins. Cell Rep. 2019;29:4632-4645.e5 pubmed publisher |
| Lambert J, Picaud S, Fujisawa T, Hou H, Savitsky P, Uusküla Reimand L, et al. Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains. Mol Cell. 2019;73:621-638.e17 pubmed publisher |
| Qin C, Hu Y, Zhou B, Fernandez Salas E, Yang C, Liu L, et al. Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression. J Med Chem. 2018;61:6685-6704 pubmed publisher |
| Berns K, Caumanns J, Hijmans E, Gennissen A, Severson T, Evers B, et al. ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors. Oncogene. 2018;37:4611-4625 pubmed publisher |
| Zhou B, Hu J, Xu F, Chen Z, Bai L, Fernandez Salas E, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018;61:462-481 pubmed publisher |
| Sakamaki J, Wilkinson S, Hahn M, Tasdemir N, O Prey J, Clark W, et al. Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function. Mol Cell. 2017;66:517-532.e9 pubmed publisher |
| Hsu S, Gilgenast T, Bartman C, Edwards C, Stonestrom A, Huang P, et al. The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries. Mol Cell. 2017;66:102-116.e7 pubmed publisher |
| Sherman M, Yu R, Tseng T, Sousa C, Liu S, Truitt M, et al. Stromal cues regulate the pancreatic cancer epigenome and metabolome. Proc Natl Acad Sci U S A. 2017;114:1129-1134 pubmed publisher |
