This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Bethyl
product type :
antibody
product name :
Rabbit anti-FBW7 Antibody, Affinity Purified
catalog :
A301-720A
quantity :
100 µg
price :
339 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunoprecipitation, western blot knockout validation
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig s1a
Allan L, Skowyra A, Rogers K, Zeller D, Clarke P. Atypical APC/C-dependent degradation of Mcl-1 provides an apoptotic timer during mitotic arrest. EMBO J. 2018;37: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4c
  • western blot; mouse; 1:1000; loading ...; fig 2b
Zhang Q, Zhang Y, Parsels J, Lohse I, Lawrence T, Pasca di Magliano M, et al. Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation. Neoplasia. 2016;18:666-673 pubmed publisher
  • western blot; human; fig s4
Broadus M, Chen T, Neitzel L, Ng V, Jodoin J, Lee L, et al. Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Cell Rep. 2016;15:1920-9 pubmed publisher
Ko Y, Kim C, Lee J, Kim D, Kim Y, Yun N, et al. Site-specific phosphorylation of Fbxw7 by Cdk5/p25 and its resulting decreased stability are linked to glutamate-induced excitotoxicity. Cell Death Dis. 2019;10:579 pubmed publisher
Huang L, Zhao J, Chen H, Wan L, Inuzuka H, Guo J, et al. SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis. Nat Commun. 2018;9:3569 pubmed publisher
Kozono S, Lin Y, Seo H, Pinch B, Lian X, Qiu C, et al. Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells. Nat Commun. 2018;9:3069 pubmed publisher
Saei A, Palafox M, Benoukraf T, Kumari N, Jaynes P, Iyengar P, et al. Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies. J Exp Med. 2018;215:1913-1928 pubmed publisher
Khan O, Carvalho J, Spencer Dene B, Mitter R, Frith D, Snijders A, et al. The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer. J Clin Invest. 2018;128:1326-1337 pubmed publisher
product information
Catalog Number :
A301-720A
Product Name :
Rabbit anti-FBW7 Antibody, Affinity Purified
Host Species :
Rabbit
Conjugation :
Unconjugated
Concentration :
100 µl at 1 mg/ml
Size :
100 µg
Packaging :
100 µl (1 mg/ml)
Buffer :
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
SpeciesSummary :
Human
Application Summary :
IP
Storage :
2 - 8° C
List Price :
339 USD
ALTnames :
AGO, archipelago, Archipelago homolog, archipelago homolog (Drosophila), CDC4, F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase, F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila), F-box and WD-40 domain-containing protein 7, F-box protein FBW7, F-box protein FBX30, F-box protein SEL-10, FBW6, FBW7, FBX30, FBXO30, FBXW6, FLJ11071, hAgo, hCdc4, homolog of C elegans sel-10, SEL10, SEL-10
Product Type :
Primary Antibodies
Immunogen :
Between 1 and 50
company information
Bethyl
25043 West FM 1097 Montgomery, TX 77356 USA
https://www.bethyl.com