Rabbit anti-MED12 Antibody, Affinity Purified | Bethyl A300-774A product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Bethyl

product type :

antibody

product name :

Rabbit anti-MED12 Antibody, Affinity Purified

catalog :

A300-774A

quantity :

100 µg

price :

339 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human; loading ...; fig 5a western blot; human; fig 1c	Donnio L, Bidon B, Hashimoto S, May M, Epanchintsev A, Ryan C, et al. MED12-related XLID disorders are dose-dependent of immediate early genes (IEGs) expression. Hum Mol Genet. 2017;26:2062-2075 pubmed publisher
	Steinparzer I, Sedlyarov V, Rubin J, Eislmayr K, Galbraith M, Levandowski C, et al. Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions. Mol Cell. 2019;76:485-499.e8 pubmed publisher
	Benabdallah N, Williamson I, Illingworth R, Kane L, Boyle S, Sengupta D, et al. Decreased Enhancer-Promoter Proximity Accompanying Enhancer Activation. Mol Cell. 2019;76:473-484.e7 pubmed publisher
	Dimitrova E, Kondo T, Feldmann A, Nakayama M, Koseki Y, Konietzny R, et al. FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment. elife. 2018;7: pubmed publisher
	Kuuluvainen E, Domènech Moreno E, Niemelä E, Makela T. Depletion of Mediator Kinase Module Subunits Represses Superenhancer-Associated Genes in Colon Cancer Cells. Mol Cell Biol. 2018;38: pubmed publisher
	Park M, Shen H, Spaeth J, Tolvanen J, Failor C, Knudtson J, et al. Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19. J Biol Chem. 2018;293:4870-4882 pubmed publisher
	Sacta M, Tharmalingam B, Coppo M, Rollins D, Deochand D, Benjamin B, et al. Gene-specific mechanisms direct glucocorticoid-receptor-driven repression of inflammatory response genes in macrophages. elife. 2018;7: pubmed publisher
	Yue J, Lai F, Beckedorff F, Zhang A, Pastori C, Shiekhattar R. Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs. Genes Dev. 2017;31:1809-1820 pubmed publisher
	Gates L, Shi J, Rohira A, Feng Q, Zhu B, Bedford M, et al. Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. J Biol Chem. 2017;292:14456-14472 pubmed publisher

product information

Catalog Number :

A300-774A

Product Name :

Rabbit anti-MED12 Antibody, Affinity Purified

Host Species :

Rabbit

Conjugation :

Unconjugated

Concentration :

100 µl at 1 mg/ml

Size :

100 µg

Packaging :

100 µl (1 mg/ml)

Buffer :

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

SpeciesSummary :

Human, Mouse

Application Summary :

WB, IP, IHC

Storage :

2 - 8° C

List Price :

339 USD

ALTnames :

activator-recruited cofactor 240 kDa component, ARC240, CAG repeat protein 45, CAGH45, FG syndrome 1, FGS1, HOPA, human opposite paired, KIAA0192, MED12S, Mediator complex subunit 12, mediator of RNA polymerase II transcription, subunit 12 homolog, OHDOX, OKS, OPA1, OPA-containing protein, putative mediator subunit 12, thyroid hormone receptor-associated protein, 230 kDa subunit, TNRC11, TRAP230, trinucleotide repeat-containing gene 11 protein

Product Type :

Primary Antibodies

Immunogen :

Between 2150 and C-term