CD159a (NKG2a) | Beckman Coulter IM2750 product information

product summary

company name :

Beckman Coulter

other brands :

Immunotech, Diagnostic Systems Laboratories

product type :

antibody

product name :

CD159a (NKG2a)

catalog :

IM2750

quantity :

0.2 mg

price :

Request Quote

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Z199

reactivity :

African green monkey, human, chimpanzee, Rhesus monkey

application :

immunocytochemistry, flow cytometry, blocking or activating experiments

more info or order :

Beckman Coulter product webpage

citations: 33

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 2a	Ingegnere T, Mariotti F, Pelosi A, Quintarelli C, De Angelis B, Tumino N, et al. Human CAR NK Cells: A New Non-viral Method Allowing High Efficient Transfection and Strong Tumor Cell Killing. Front Immunol. 2019;10:957 pubmed publisher
flow cytometry; human; loading ...; tbl s1	Dias J, Boulouis C, Gorin J, van den Biggelaar R, Lal K, Gibbs A, et al. The CD4-CD8- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool. Proc Natl Acad Sci U S A. 2018;115:E11513-E11522 pubmed publisher
flow cytometry; human; loading ...; fig 2b	Mahaweni N, Ehlers F, Sarkar S, Janssen J, Tilanus M, Bos G, et al. NKG2A Expression Is Not per se Detrimental for the Anti-Multiple Myeloma Activity of Activated Natural Killer Cells in an In Vitro System Mimicking the Tumor Microenvironment. Front Immunol. 2018;9:1415 pubmed publisher
flow cytometry; Rhesus monkey; fig 1b	Manickam C, Nwanze C, Ram D, Shah S, Smith S, Jones R, et al. Progressive lentivirus infection induces natural killer cell receptor-expressing B cells in the gastrointestinal tract. AIDS. 2018;32:1571-1578 pubmed publisher
immunocytochemistry; African green monkey; loading ...; fig s9d	Ferrando Martinez S, Moysi E, Pegu A, Andrews S, Nganou Makamdop K, Ambrozak D, et al. Accumulation of follicular CD8+ T cells in pathogenic SIV infection. J Clin Invest. 2018;128:2089-2103 pubmed publisher
flow cytometry; human; loading ...; fig 3a	Oei V, Siernicka M, Graczyk Jarzynka A, Hoel H, Yang W, Palacios D, et al. Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors. Cancer Immunol Res. 2018;6:467-480 pubmed publisher
flow cytometry; human; loading ...; fig s1	Chan Y, Zuo J, Inman C, Croft W, Begum J, Croudace J, et al. NK cells produce high levels of IL-10 early after allogeneic stem cell transplantation and suppress development of acute GVHD. Eur J Immunol. 2018;48:316-329 pubmed publisher
flow cytometry; human; fig 2	Kyoizumi S, Kubo Y, Kajimura J, Yoshida K, Hayashi T, Nakachi K, et al. Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors. J Immunol. 2017;199:2777-2793 pubmed publisher
flow cytometry; human; loading ...; fig 3c	van der Geest K, Wang Q, Eijsvogels T, Koenen H, Joosten I, Brouwer E, et al. Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study. Immun Ageing. 2017;14:5 pubmed publisher
flow cytometry; human; loading ...; fig 1a	Isitman G, Tremblay McLean A, Lisovsky I, Bruneau J, Lebouché B, Routy J, et al. NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts. PLoS ONE. 2016;11:e0164517 pubmed publisher
flow cytometry; Rhesus monkey; loading ...; fig 1a	Vargas Inchaustegui D, Ying O, Demberg T, Robert Guroff M. Evaluation of Functional NK Cell Responses in Vaccinated and SIV-Infected Rhesus Macaques. Front Immunol. 2016;7:340 pubmed publisher
flow cytometry; human; loading ...; fig 4d	Landtwing V, Raykova A, Pezzino G, Beziat V, Marcenaro E, Graf C, et al. Cognate HLA absence in trans diminishes human NK cell education. J Clin Invest. 2016;126:3772-3782 pubmed publisher
flow cytometry; human; loading ...; fig 1c	Hervier B, Perez M, Allenbach Y, Devilliers H, Cohen F, Uzunhan Y, et al. Involvement of NK Cells and NKp30 Pathway in Antisynthetase Syndrome. J Immunol. 2016;197:1621-30 pubmed publisher
flow cytometry; Rhesus monkey; loading ...; fig 4b	DeGottardi M, Okoye A, Vaidya M, Talla A, Konfe A, Reyes M, et al. Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques. J Immunol. 2016;197:1183-98 pubmed publisher
flow cytometry; African green monkey; loading ...; fig 2a	Neumann B, Shi T, Gan L, Klippert A, Daskalaki M, Stolte Leeb N, et al. Comprehensive panel of cross-reacting monoclonal antibodies for analysis of different immune cells and their distribution in the common marmoset (Callithrix jacchus). J Med Primatol. 2016;45:139-46 pubmed publisher
flow cytometry; human; loading ...; fig 2a	Rettman P, Willem C, David G, Riou R, Legrand N, Esbelin J, et al. New insights on the natural killer cell repertoire from a thorough analysis of cord blood cells. J Leukoc Biol. 2016;100:471-9 pubmed publisher
flow cytometry; human; loading ...	Tham M, SchlÃ¶r G, Yerly D, Mueller C, Surbek D, Villiger P, et al. Reduced pro-inflammatory profile of Î³Î´T cells in pregnant patients with rheumatoid arthritis. Arthritis Res Ther. 2016;18:26 pubmed publisher
flow cytometry; Rhesus monkey; loading ...; fig 5a	Evans T, Li H, Schafer J, Klatt N, Hao X, Traslavina R, et al. SIV-induced Translocation of Bacterial Products in the Liver Mobilizes Myeloid Dendritic and Natural Killer Cells Associated With Liver Damage. J Infect Dis. 2016;213:361-9 pubmed publisher
flow cytometry; human; fig 6	Yawata N, Selva K, Liu Y, Tan K, Lee A, Siak J, et al. Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection. Mucosal Immunol. 2016;9:159-70 pubmed publisher
flow cytometry; human; fig 2	Marquardt N, BÃ©ziat V, NystrÃ¶m S, Hengst J, Ivarsson M, KekÃ¤lÃ¤inen E, et al. Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells. J Immunol. 2015;194:2467-71 pubmed publisher
flow cytometry; human; tbl s5	Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, et al. Effector VÎ³9VÎ´2 T cells dominate the human fetal Î³Î´ T-cell repertoire. Proc Natl Acad Sci U S A. 2015;112:E556-65 pubmed publisher
flow cytometry; human	Hagberg N, Theorell J, Hjorton K, Spee P, Eloranta M, Bryceson Y, et al. Functional anti-CD94/NKG2A and anti-CD94/NKG2C autoantibodies in patients with systemic lupus erythematosus. Arthritis Rheumatol. 2015;67:1000-11 pubmed publisher
flow cytometry; human	Lim D, Yawata N, Selva K, Li N, Tsai C, Yeong L, et al. The combination of type I IFN, TNF-Î±, and cell surface receptor engagement with dendritic cells enables NK cells to overcome immune evasion by dengue virus. J Immunol. 2014;193:5065-75 pubmed publisher
flow cytometry; human	Sullivan E, Jeha S, Kang G, Cheng C, Rooney B, Holladay M, et al. NK cell genotype and phenotype at diagnosis of acute lymphoblastic leukemia correlate with postinduction residual disease. Clin Cancer Res. 2014;20:5986-94 pubmed publisher
flow cytometry; human	Alnabhan R, Madrigal A, Saudemont A. Differential activation of cord blood and peripheral blood natural killer cells by cytokines. Cytotherapy. 2015;17:73-85 pubmed publisher
flow cytometry; African green monkey; fig s1	Jacquelin B, Petitjean G, Kunkel D, Liovat A, Jochems S, Rogers K, et al. Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection. PLoS Pathog. 2014;10:e1004241 pubmed publisher
blocking or activating experiments; human	Celis Gutierrez J, Boyron M, Walzer T, Pandolfi P, Jonjic S, Olive D, et al. Dok1 and Dok2 proteins regulate natural killer cell development and function. EMBO J. 2014;33:1928-40 pubmed publisher
flow cytometry; human	Ito S, Bollard C, Carlsten M, Melenhorst J, Biancotto A, Wang E, et al. Ultra-low dose interleukin-2 promotes immune-modulating function of regulatory T cells and natural killer cells in healthy volunteers. Mol Ther. 2014;22:1388-1395 pubmed publisher
flow cytometry; chimpanzee	Hodara V, Parodi L, Chavez D, Smith L, Lanford R, Giavedoni L. Characterization of ??T cells in naïve and HIV-infected chimpanzees and their responses to T-cell activators in vitro. J Med Primatol. 2014;43:258-71 pubmed publisher
flow cytometry; human; fig 3	Loh L, Ivarsson M, Michaelsson J, Sandberg J, Nixon D. Invariant natural killer T cells developing in the human fetus accumulate and mature in the small intestine. Mucosal Immunol. 2014;7:1233-43 pubmed publisher
flow cytometry; African green monkey; loading ...; fig 9	Trist H, Tan P, Wines B, Ramsland P, Orlowski E, Stubbs J, et al. Polymorphisms and interspecies differences of the activating and inhibitory Fc?RII of Macaca nemestrina influence the binding of human IgG subclasses. J Immunol. 2014;192:792-803 pubmed publisher
flow cytometry; human	Cairo C, Longinaker N, Cappelli G, Leke R, Ondo M, Djokam R, et al. Cord blood V?2V?2 T cells provide a molecular marker for the influence of pregnancy-associated malaria on neonatal immunity. J Infect Dis. 2014;209:1653-62 pubmed publisher
	Foley B, Cooley S, Verneris M, Curtsinger J, Luo X, Waller E, et al. Human cytomegalovirus (CMV)-induced memory-like NKG2C(+) NK cells are transplantable and expand in vivo in response to recipient CMV antigen. J Immunol. 2012;189:5082-8 pubmed publisher

product information

Catalog Number :

IM2750

Product Name :

CD159a (NKG2a)

Species Specificity :

Human

Host Species :

Mouse

Clonality :

Monoclonal

Conjugation :

Purified

Labeling :

ASR

Product Type :

Antibody

Size :

0.2 mg

List Price :

Request Quote

Clone :

Z199

Isotype :

IgG2b

Product Description :

Mouse Anti-Human CD159a

ALTnames :

NKG2a

Immunogen :

NK clone

Specificity :

Reacts with CD94brigth NK cells, expressing the CD159a/CD94 inhibitory receptor complex

Storage :

2-8°C

General Research References :

1. Moretta, A., Moretta, L., 1997, Curr. Opin. Immunol., 9, 694-701. 2. Yokoyama, W.M., 1998, Curr. Opin. Immunol., 10, 298-305. 3. Moretta, A., Biassoni, R., Bottino, C., Pende, D., itale, M., Poggi, A., Mingari, M.C., Moretta, L., 1997, Immunol. Rev., 155, 105-117. 4. Sivori, S., Vitale, M., Bottino, C., Marcenaro, E., Sanseverino, L., Parolini, S., Moretta, L., Moretta, A., 1996, Eur. J. Immunol., 26, 2487-2492. 5. Perez-Villar, J.J., Carretero, M., Navarro, F., Melero, I., Rodriguez, A., Bottino, C., Moretta, A., Lopez-Botet, M., 1996, J. Immunol., 157, 5367-5374. 6. Braud, V.M., Allan, D.S.J., O'Callagan, C.A., Söderström, K., D'Andrea, A., Ogg, G.S., Lazetic, S., Young, N.T., Bell, J.I., Phillips, J.H., Lanier, L.L., McMichael, A.J., 1998, Nature, 319, 795-799. 7. Lee, N., Llano, M., Carretero, M., Ishitani, A., Navarro, F., Lopez-Botet, M., Geraghty, D.E., 1998, Proc. Natl. Acad. Sci., 95, 5199-5204. 8. Mingari, M.C., Ponte, M., Cantoni, C., Vitale, C., Schiavetti, F., Bertone, S., Bellomo, R., Cappai, A.T., Biassoni, R., 1997, Int. Immunol., 9, 485-491. 9. Pérez-Villar, J.J., Melero, I., Navarro, F., Carretero, M., Bellon, T., Llano, M., Colonna, M., Geraghty, D.E., Lopez- Botet, M., 1997, J. Immunol., 158, 5736-5743. 10. Pende, D., Silvori, S., Accame, L., Pareti, L., Falco, M., Le Bouteiller, P., Moretta, L., Moretta, A., 1997, Eur. J. Immunol., 27, 1875-1880. 11. Pascal, V., Vivier, E., André, P., 2002, Leucocyte Typing VII, White Cell Differentiation Antigens. Mason, D., et al, Eds., Oxford, Inc., 417-418.

more info or order :

Beckman Coulter product webpage