product summary
company name :
Beckman Coulter
other brands :
Immunotech, Diagnostic Systems Laboratories
product type :
antibody
product name :
CD244 (2B4)
catalog :
IM1607
quantity :
0.2 mg
price :
Request Quote
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C1.7
reactivity :
human
application :
immunoprecipitation, flow cytometry, blocking or activating experiments
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 3a
Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren H, Sonnerborg A, et al. Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals. Sci Rep. 2017;7:40354 pubmed publisher
  • blocking or activating experiments; human; loading ...; fig s14b
  • flow cytometry; human
Kwon H, Choi G, Ryu S, Kwon S, Kim S, Booth C, et al. Stepwise phosphorylation of p65 promotes NF-?B activation and NK cell responses during target cell recognition. Nat Commun. 2016;7:11686 pubmed publisher
  • flow cytometry; human
Pombo C, Wherry E, Gostick E, Price D, Betts M. Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+ T-Cell Population in Elite Controllers. J Infect Dis. 2015;212:1376-86 pubmed publisher
  • immunoprecipitation; human
Gütgemann S, Sandusky M, Wingert S, Claus M, Watzl C. Recruitment of activating NK-cell receptors 2B4 and NKG2D to membrane microdomains in mammalian cells is dependent on their transmembrane regions. Eur J Immunol. 2015;45:1258-69 pubmed publisher
  • blocking or activating experiments; human
Celis Gutierrez J, Boyron M, Walzer T, Pandolfi P, Jonjic S, Olive D, et al. Dok1 and Dok2 proteins regulate natural killer cell development and function. EMBO J. 2014;33:1928-40 pubmed publisher
  • blocking or activating experiments; human
Awad A, Yassine H, Barrier M, Vorng H, Marquillies P, Tsicopoulos A, et al. Natural killer cells induce eosinophil activation and apoptosis. PLoS ONE. 2014;9:e94492 pubmed publisher
  • flow cytometry; human
Prinz P, Mendler A, Brech D, Masouris I, Oberneder R, Noessner E. NK-cell dysfunction in human renal carcinoma reveals diacylglycerol kinase as key regulator and target for therapeutic intervention. Int J Cancer. 2014;135:1832-41 pubmed publisher
Bryceson Y, March M, Barber D, Ljunggren H, Long E. Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells. J Exp Med. 2005;202:1001-12 pubmed
Watzl C, Long E. Natural killer cell inhibitory receptors block actin cytoskeleton-dependent recruitment of 2B4 (CD244) to lipid rafts. J Exp Med. 2003;197:77-85 pubmed
product information
Catalog Number :
IM1607
Product Name :
CD244 (2B4)
Species Specificity :
Human
Host Species :
Mouse
Clonality :
Monoclonal
Conjugation :
Purified
Labeling :
RUO
Product Type :
Antibody
Size :
0.2 mg
List Price :
Request Quote
Clone :
C1.7
Isotype :
IgG1
Product Description :
Mouse Anti-Human CD244
ALTnames :
2B4
Immunogen :
Cultured human NK cells
Specificity :
Recognizes a 38 kDa cell surface signal transduction molecule (p38) found on all human NK-cells
Applications :
Flow Cytometry
Storage :
2-8°C
General Research References :
1. Valiante, N.M., Trinchieri, G. 1993, J. Exp. Med., 178, 1397-1406.
more info or order :
company information
Beckman Coulter
11800 S.W. 147th Avenue
Miami FL 33196
www.beckmancoulter.com
305 380-3800
headquarters: United States